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北京大学学报(医学版) ›› 2017, Vol. 49 ›› Issue (5): 878-882. doi: 10.3969/j.issn.1671-167X.2017.05.024

• 论著 • 上一篇    下一篇

iPlan CMF软件辅助下增强CT三维重建在头颈部肿瘤治疗中的应用

于尧, 章文博, 王洋, 刘筱菁, 郭传瑸, 俞光岩, 彭歆   

  1. 北京大学口腔医学院·
    口腔医院,口腔颌面外科 口腔数字化医疗技术和材料国家工程实验室 口腔数字医学北京市重点实验室,北京 100081
  • 收稿日期:2016-05-16 出版日期:2017-10-18 发布日期:2017-10-18
  • 基金资助:
    国家科技支撑计划(2014BAI04B06)和北京市科委首都市民健康培育项目 (Z161100000116053)资助

Application of three-dimensional reconstruction of the enhanced CT with iPlan CMF software in head and neck neoplasms

YU Yao, ZHANG Wen-bo, WANG Yang, LIU Xiao-jing, GUO Chuan-bin, YU Guang-yan, PENG Xin   

  1. Department of Oral and Maxilloficial Surgery, Peking University School and Hospital of Stomatology &
    National Enginee-ring Laboratory for Digital and Material Technology of Stomatology &
    Beijing Key Laboratory of Digital Stomatology, Beijing 100081,China
  • Received:2016-05-16 Online:2017-10-18 Published:2017-10-18

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摘要： 目的 应用iPlan CMF软件重建头颈部肿瘤患者增强CT影像中的肿物及周围重要解剖结构,探讨iPlan CMF指导下增强CT三维重建技术在头颈部肿瘤手术治疗中的临床意义。方法 选取2014年6月至2015年6月就诊于北京大学口腔医学院口腔颌面外科的13例头颈部肿瘤紧邻重要神经、血管的患者,利用Seimens 16排螺旋CT薄层扫描技术,以额定扫描参数完成头颈部增强扫描,iPlan CMF软件直接读入Dicom格式原始数据,利用表面阴影重建法分别重建肿瘤、血管、骨骼及其他重要解剖结构,显示其术前三维空间关系,测量标记肿瘤与重要血管等解剖结构的距离,视肿瘤观察需要可行虚拟截骨,完成肿瘤暴露,设计手术入路,用以指导术前准备及手术。收集13例患者的术前准备、术中情况及术后并发症情况。结果 13例患者中,男6例,女7例,年龄23~65岁,中位年龄50岁。观察三维重建图像,可以清晰显示肿瘤范围、大小、位置及其与周围临近重要解剖结构的关系,根据三维重建图像,评估13例患者的手术风险,3例患者经过肿瘤三维重建等术前评估,建议综合治疗;10例患者完成术前准备并成功完成手术,其中3例患者术前备血及术中输血,2例患者邀请神经外科、胸外科协助手术,10例患者手术平均用时(202±135) min,手术平均出血(235±252) mL,三维标记与术中情况符合率为100%,其中1例患者由于肿瘤来源于迷走神经,术后出现声音嘶哑,其余患者未出现手术并发症。结论 利用iPlan CMF软件三维重建增强CT可以清楚显示头颈部深大肿瘤的特征及其与周围重要解剖结构的关系,有利于手术方案的设计,避免术中损伤重要解剖结构,减少术后并发症的产生。

关键词: 头颈部肿瘤, 动态增强计算机断层扫描, 三维重建

Abstract: Objective: Three-dimensional reconstruction of the enhanced CT is increasingly becoming a valuable tool in head and neck neoplasms. The aim of this study is to reconstruct three-dimensional imaging of tumor and its surrounding important anatomical structure using iPlan CMF software, and to investigate the application of three-dimensional tumor mapping technique for the diagnosis and treatment of the head and neck neoplasms. Methods: In the study, 13 cases with head and neck tumors in Department of Oral and Maxilloficial Surgery, Peking University School and Hospital of Stomatology from June 2014 to June 2015 were studied using spiral CT scanning technology based on the same scanning condition. iPlan CMF software was used to read the original CT data, and surface shaded technology was applied to reconstruct the spatial relationship of the tumor, vessel and skull. The distance between the tumor and its surrounding important anatomical structure could be measured. iPlan CMF software was also used to accomplish the virtual osteotomy to expose the tumor, vessel and skull. The preoperative preparation, operative situation and postoperative complication were reviewed. Results: In this study 6 patients were male and 7 female. The age range was from 23 to 65 years, and the median patient age was 50 years. The three-dimensional reconstruction image clearly demonstrated the extent of the tumor size, location, and the relation to its surrounding important anatomical structure. According to the three-dimensional image, the surgical risk of the patients was evaluated. The preoperative preparation and surgeries were successfully performed for 10 patients. Blood transfusion for 3 patients was considered before the surgery and actually accomplished during the operation. The operations for 2 patients were performed with the help of doctors from other departments. Only one patient had hoarseness because the tumor resulted from the pneumogastric nerves. For 10 patients, the average operation time was (202±135) min, and the average operation bleeding was (235±252) mL. The other 3 patients were not suitable cases for surgery. Conclusion: The three-dimensional reconstruction of enhanced CT image with iPlan CMF software is very helpful to make the treatment plan to avoid damaging important anatomical structures and postoperative complications.

Key words: Head and neck neoplasms, Contrast-enhanced computed tomography, Three-dimensional reconstruction

中图分类号: 

  • R782.05
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