MAPK和AKT磷酸化下调参与Toll样受体抑制的人牙周膜干细胞的成骨分化

朱云艳, 李倩, 张怡美, 周彦恒^△

Decreased phosphorylation of mitogen activated protein kinase and protein kinase B contribute to the inhibition of osteogenic differentiation mediated by activation of Toll like receptor in human periodontal ligament stem cells

ZHU Yun-yan, LI Qian, ZHANG Yi-mei, ZHOU Yan-heng^△

高浓度TLR1、TLR2、TLR 3、TLR 4、TLR 6配体刺激显著地降低了hPDLSCs的碱性磷酸酶染色水平,成骨诱导7 d的碱性磷酸酶染色结果