MAPK和AKT磷酸化下调参与Toll样受体抑制的人牙周膜干细胞的成骨分化

朱云艳, 李倩, 张怡美, 周彦恒^△

Decreased phosphorylation of mitogen activated protein kinase and protein kinase B contribute to the inhibition of osteogenic differentiation mediated by activation of Toll like receptor in human periodontal ligament stem cells

ZHU Yun-yan, LI Qian, ZHANG Yi-mei, ZHOU Yan-heng^△

成骨诱导14 d的茜素红染色发现高浓度TLR1, TLR 2, TLR 3, TLR 4, TLR 6的配体刺激显著降低了hPDLSCs的茜素红染色水平(×100; 标尺: 200 μm)