中国人群遗传性周围神经病的致病基因分布
刘小璇,段晓慧,张朔,孙阿萍,张英爽,樊东升

Genetic distribution in Chinese patients with hereditary peripheral neuropathy
Xiao-xuan LIU,Xiao-hui DUAN,Shuo ZHANG,A-ping SUN,Ying-shuang ZHANG,Dong-sheng FAN
表1 HPN各临床类型的流行病学资料
Table 1 Epidemiological data of clinical types of HPN
Phenotype n (%) Age of onset/years Age of examination/years Disease course/years CMTNS-v2
HPN 666 (100) 24.9±17.6 34.3±17.8 9.0±9.4 11.3±5.3
  CMT 495 (74.3) 24.6±18.0 33.4±17.2 8.7±9.0 12.2±5.6
  HMN 107 (16.1) 25.6±17.0 35.4±18.2 9.4±9.5 8.9±5.0
  HNPP 39 (5.9) 27.6±11.0 32.4±12.2 4.4±2.5 8.4±2.9
  HSAN 17 (2.6) 31.5±11.0 38.4±15.2 10.4±9.5 11.8±9.4
  FAP 7 (1.1) 52 (11-78) 55 (12-83) 5.4±2.5 16.8±9.5
  Refsum 1 25 35 10 16