Abstract: To investigate the correlation of human oocyte morphometric parameters with fertilization and embryo development in the intracytoplasmic sperm injection (ICSI) cycles. Methods: The morphometric parameters of oocytes collected and submitted to evaluation using OCTAX Eye-ware software just before ICSI. Oocyte diameter (OD), perivitelline space width (PSW), zonapellucida thickness (ZPT) and the shape of first polar body (FPB) (intact or fragmented) were analyzed. A stepwise multivariate Logistic regression was used to test the association between the morphometric parameters and fertilization and embryo development. Results: In the study, 436 oocytes were measured and 370 were ferti-lized (84.9%), 225 fertilized oocytes were developed to high-quality embryos (60.8%). ZPT and PSW were associated with fertilization. The oocytes fertilized had thicker ZPT ［(18.0±2.3) μm vs. (16.9±2.7) μm］ and wider PSW ［(14.4±3.3) μm vs. (13.2±3.9) μm］. The OD and shape of FPB were associated with embryos development. The oocytes developed to high-quality embryos had larger OD ［(116.6±3.7) μm vs. (114.7±3.6) μm］ and more intact FPB (86.2% vs. 66.7%). Conclusion: The morphometric parameters of oocytes can indicate fertilization and embryo development.

Key words: Oocytes, Fertilization in vitro, Embryonic development