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Journal of Peking University(Health Sciences) >

2021 , Vol. 53 >Issue 4: 653 - 658

DOI: https://doi.org/10.19723/j.issn.1671-167X.2021.04.005

Quality of life and related factors in patients with interstitial cystitis/bladder pain syndrome

  • Jia-wen WANG ,
  • Jing-chao LIU ,
  • Ling-feng MENG ,
  • Wei ZHANG ,
  • Xiao-dong LIU ,
  • Yao-guang ZHANG
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  • 1. Department of Urology, Peking University Fifth School of Clinical Medicine, Beijing Hospital, Beijing 100730, China
    2. National Center of Gerontology, Beijing Hospital Continence Center, Beijing 100730, China

Received date: 2021-03-08

  Online published: 2021-08-25

Supported by

National Key Research and Development Program of China(2018YFC2002200)

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Abstract

Objective: To evaluate the quality of life of patients with interstitial cystitis/bladder pain syndrome (IC/BPS), to compare the difference between IC/BPS and overactive bladder (OAB) pain syndrome, and to explore the related factors affecting the quality of life of IC/BPS patients. Methods: The demographic data of female outpatients with IC/BPS in Beijing Hospital and other medical centers in China were collected. The quality of life of the patients was investigated by multi-angle questionnaires and compared with the data of OAB patients. According to the influence degree of quality of life, the patients with IC/BPS were divided into mild-moderate group and severe group. Results: In this study, 109 patients with IC/BPS were included. The average age was (46.4±14.3) years and the average course of disease was (39.4±51.6) months. Compared with the OAB patients, the patients in IC/BPS group had a longer average course of disease (P=0.008), a lower proportion of the patients of first visit for the disease (P<0.001), a higher score of the American Urological Association symptom index (AUA-SI) (P<0.001), a lower body mass index (BMI) ratio (P=0.016), and a lower incidence of constipation (P=0.006). IC/BPS had the greatest impact on family life, followed by social activity. The score of IC/BPS related symptoms on family life was significantly higher than that of the OAB group (P=0.003). The top three symptoms of the IC/BPS patients were pain (45%), frequency (28%) and urgency (17%). The score of quality of life in the IC/BPS patients was significantly higher than that in the OAB patients (P<0.001). Caffeine intake (P=0.034) and constipation (P=0.003) might be the factors influencing the quality of life of the patients with IC/BPS. Conclusion: IC/BPS has a great influence on the quality of life of patients. Caffeine intake and constipation may be related factors affecting the quality of life of patients with IC/BPS. Urologists should recommend changes in diet and lifestyle to reduce symptoms and improve the patients’ quality of life.

Key words： Interstitial cystitis; Urinary bladder; overactive; Quality of life; Risk factors

Cite this article

Jia-wen WANG , Jing-chao LIU , Ling-feng MENG , Wei ZHANG , Xiao-dong LIU , Yao-guang ZHANG . Quality of life and related factors in patients with interstitial cystitis/bladder pain syndrome[J]. Journal of Peking University(Health Sciences), 2021 , 53(4) : 653 -658 . DOI: 10.19723/j.issn.1671-167X.2021.04.005

References

[1] Davis NF, Brady CM, Creagh T. Interstitial cystitis/painful bladder syndrome: Epidemiology, pathophysiology and evidence-based treatment options [J]. Eur J Obstet Gynecol Reprod Biol, 2014, 175:30-37
[2] Berry SH, Elliott MN, Suttorp M, et al. Prevalence of symptoms of bladder pain syndrome/interstitial cystitis among adult females in the United States [J]. J Urol, 2011, 186(2):540-544.
[3] Tripp DA, Nickel JC, Krsmanovic A, et al. Depression and catastrophizing predict suicidal ideation in tertiary care patients with interstitial cystitis/bladder pain syndrome [J]. Can Urol Assoc J, 2016, 10(11/12):383-388.
[4] Hanno PM, Erickson D, Moldwin R, et al. Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment [J]. J Urol, 2015, 193(5):1545-1553.
[5] Gormley EA, Lightner DJ, Faraday M, et al. Diagnosis and treatment of overactive bladder (non-neurogenic) in adults: AUA/SUFU guideline amendment [J]. J Urol, 2015, 193(5):1572-1580.
[6] Hung MJ, Chou CL, Yen TW, et al. Development and validation of the Chinese Overactive Bladder Symptom Score for assessing overactive bladder syndrome in a RESORT study [J]. J Formos Med Assoc, 2013, 112(5):276-282.
[7] Jhang JF, Kuo HC. Pathomechanism of interstitial cystitis/bladder pain syndrome and mapping the heterogeneity of disease [J]. Int Neurourol J, 2016, 20(Suppl 2):S95-S104.
[8] Birder LA. Pathophysiology of interstitial cystitis [J]. Int J Urol, 2019, 26(Suppl 1):12-15.
[9] 那彦群, 叶章群, 孙颖浩, 等. 膀胱过度活动症诊断与治疗指南 [M]. 北京: 人民卫生出版社, 2014: 330-335.
[10] Hagovska M, Švihra J, Buková A, et al. The relationship between overweight and overactive bladder symptoms [J]. Obes Facts, 2020, 13(3):297-306.
[11] Raju R, Linder BJ. Evaluation and treatment of overactive bladder in women [J]. Mayo Clin Proc, 2020, 95(2):370-377.
[12] Beckett MK, Elliot MN, Clemens JQ, et al. Consequences of interstitial cystitis/bladder pain symptoms on women’s work participation and income: Results from National Household Sample [J]. J Urol, 2014, 191(1):83-88.
[13] Vasudevan V, Moldwin R. Addressing quality of life in the patient with interstitial cystitis/bladder pain syndrome [J]. Asian J Urol, 2017, 4(1):50-54.
[14] McKernan LC, Walsh CG, Reynolds WS, et al. Psychosocial co-morbidities in interstitial cystitis/bladder pain syndrome (IC/BPS): A systematic review [J]. Neurourol Urodyn, 2018, 37(3):926-941.
[15] Watkins KE, Eberhart N, Hilton L, et al. Depressive disorders and panic attacks in women with bladder pain syndrome/interstitial cystitis: A population-based sample [J]. Gen Hosp Psychiatry, 2011, 33(2):143-149.
[16] Naliboff BD, Stephens AJ, Afari N, et al. Widespread psychosocial difficulties in men and women with urologic chronic pelvic pain syndromes: Case-control findings from the multidisciplinary approach to the study of chronic pelvic pain research network [J]. Urology, 2015, 85(6):1319-1327.
[17] Yu WR, Peng TC, Yeh HL, et al. Anxiety severity does not influence treatment outcomes in patients with interstitial cystitis/bladder pain syndrome [J]. Neurourol Urodyn, 2019, 38(6):1602-1610.
[18] Thong ISK, Jensen MP, Miró J, et al. The validity of pain intensity measures: What do the NRS, VAS, VRS, and FPS-R mea-sure? [J]. Scand J Pain, 2018, 18(1):99-107.
[19] Ölçücü MT, Aydın ME, Avcı S, et al. Comparison of a visual prostate symptom score and international prostate symptom score: A prospective multicenter study and literature review [J]. Urology, 2020, 146:230-235.
[20] 张维宇, 王焕瑞, 刘献辉, 等. 尿流率视觉量表的开发 [J]. 北京大学学报(医学版), 2020, 52(4):684-687.
[21] Thu JHL, Vetter J, Lai HH. The severity and distribution of nonurologic pain and urogenital pain in overactive bladder are intermediate between interstitial cystitis and controls [J]. Urology, 2019, 130:59-64.
[22] Shorter B, Lesser M, Moldwin R, et al. Effect of comestibles on symptoms of interstitial cystitis [J]. J Urol, 2007, 178(1):145-152.
[23] Friedlander JI, Shorter B, Moldwin RM. Diet and its role in interstitial cystitis/bladder pain syndrome (IC/BPS) and comorbid conditions [J]. BJU Int, 2012, 109(11):1584-1591.
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