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Associations between early onset of puberty and obesity types in children: Based on both the cross-sectional study and cohort study
Received date: 2022-06-13
Online published: 2022-10-14
Supported by
the National Natural Science Foundation of China(81673192);the Research Special Fund for Public Welfare Industry of Health of the Ministry of Health of China(201202010)
Objective: To explore and analyze the relationship between early onset of puberty and different types of obesity in children, by combining large sample cross-sectional survey data with long-term longitudinal cohort data, so as to provide clues for further clarifying the health hazards of early onset of puberty and obesity prevention and control. Methods: The research data were from the cross-sectional survey data of seven provinces(autonomous regions, municipalities) in China and the cohort data of adolescent development in Xiamen. The study first found the association between early onset of puberty and obesity by Logistic regression on the cross-sectional data, and then used Poisson regression to analyze the association between early puberty initiation and various types of obesity risk. Results: In the study, 43 137 and 1 266 children were included in the cross-sectional survey and cohort survey respectively. The cross-sectional study found that among the girls aged 10-13 years, compared with the girls of the same age who did not start puberty, the body mass index (BMI)-Z score of the girls in the puberty start group was 0.5-0.8 higher, and the waist circumference Z score was 0.4-0.7 higher, and the risk of various types of obesity was higher. At the same time, the early onset of puberty was positively correlated with simple obesity, central obesity and compound obesity, the OR (95%CI) were 1.86 (1.42-2.44), 1.95 (1.65-2.32) and 1.86 (1.41-2.45), respectively. No significant association was found in boys. According to the cohort data, in girls, the risk of simple obesity was 6.00 times [RR (95%CI): 6.00 (1.07-33.60)], the risk of central obesity was 3.30 times [RR (95%CI): 3.30 (1.22-8.92)], and the risk of compound obesity was 5.76 times [RR (95%CI): 5.76 (1.03-32.30)], compared with the group without early puberty initiation, while no association between early puberty initiation and obesity was found in boys. Conclusion: Based on the cross-sectional survey and longitudinal cohort survey, it is confirmed that the early onset of puberty in girls may increase the risk of simple obesity, central obesity and compound obesity, while there is no significant correlation between puberty onset and obesity in boys.
Key words： Pediatric obesity; Puberty; Children; Cross-sectional studies; Cohort studies
Tao MA , Yan-hui LI , Man-man CHEN , Ying MA , Di GAO , Li CHEN , Qi MA , Yi ZHANG , Jie-yu LIU , Xin-xin WANG , Yan-hui DONG , Jun MA . Associations between early onset of puberty and obesity types in children: Based on both the cross-sectional study and cohort study[J]. Journal of Peking University(Health Sciences), 2022 , 54(5) : 961 -970 . DOI: 10.19723/j.issn.1671-167X.2022.05.025
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