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Journal of Peking University(Health Sciences) ›› 2014, Vol. 46 ›› Issue (4): 642-645.

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Micropump infusion of gonadorelin in the treatment of hypogonadotropic hypogonadism in patients with pituitary stalk interruption syndrome: cases analysis and literature review

SHAO Wei-min1, 2，BAI Wen-jun1△,CHEN Yi-min3，LIU Lei4，WANG Yu-jie2△   

  1. （1.Department of Urology, Peking University People’s Hospital, Beijing 10044,China; 2.Center of Urology,The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China; 3.Department of Urology, Chaozhou People’s Hospital, Guangdong Chaozhou 521000,China; 4.Department of Urology, The First Hospital of Zhengzhou, Henan, Zhengzhou 450004, China）
  • Online:2014-08-18 Published:2014-08-18

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Abstract: Two cases of hypogonadotropic hypogonadism caused by pituitary stalk interruption syndrome treated by pulse infusion of gonadorelin via micropump were reported, and their clinical features and the treatment process of pulse infusion of gonadorelin via micropump summarized. Both of the 2 patients were presented primarily with hypogonadotropic hypogonadism. After the treatment with pulse infusion of gonadorelin via micropump, their syndrome of androgen deficiency improved and the gonadotropin levels promoted at the end of 12 weeks’ follow-up. Pulse infusion of gonadorelin via micropump is an alternative to treat hypogonadotropic hypogonadism caused by pituitary stalk interruption syndrome.

Key words: Hypogonadism, Pituitary gland, Gonadotropin-releasing hormone, Infusion pumps

[1] REN Yun, YANG Shuo, YANG Rui, LI Rong, CHEN Xin-na, WANG Hai-yan, MA Cai-hong, LIU Ping, QIAO Jie. Comparison of gonadotropin releasing hormone agonist long protocol and gonadotropin releasing hormone antagonist protocol in infertile women [J]. Journal of Peking University(Health Sciences), 2013, 45(6): 877-881.
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