Abstract: Objective： To compare the effects between dezocine and flurbiprofen axetil on postoperative sore throat (POST) after maxillofacial procedures. Methods: In the study, 90 adult patients with maxillofacial diseases were divided randomly into control group (group C), flurbiprofen group (group F) and dezocine group (group D). Physiological saline, flurbiprofen axetil (1 mg/kg) and dezocine (0.1 mg/kg) were administered intravenously for each group 30 minutes before the end of the operation. We recorded visual analogue scale (VAS) and Bruggrmann comfort scale (BCS) at the time points of 0.5 h, 1 h, 2 h, and 6 h after extubation. Results: The incidence of POST in group D decreased significantly (P<0.05). There was no difference between the incidences of groups F and C. The VAS of group F was lower than that of group C (P<0.01) just at the time points of 0.5 h and 1 h after extubation, from then on, there was no difference between the 2 groups. The VAS of group D was lower than that of group F, and the BCS was higher than that of group F significantly. Conclusion: Dezocine has notable analgesia effect for postoperative sore throat, so it is a better choice to carry out postoperative analgesia after maxillofacial procedures.

Key words: Dezocine, Flurbiprofen, Intubation, intratracheal, Oral surgical procedures, Pharyngitis