Journal of Peking University (Health Sciences) ›› 2023, Vol. 55 ›› Issue (5): 943-947. doi: 10.19723/j.issn.1671-167X.2023.05.026

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振华 刘*(),建伟 王,广林 黄,贵忠 李,立波 满   

  • Received:2023-03-02 Online:2023-10-18 Published:2023-10-09
  • Contact: 振华 刘 E-mail:liuzhenh@126.com
  • Supported by:
    the Beijing Municipal Administration of Hospital Incubating Program(PX2021017)

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CLC Number: 

  • R691.3

Table 1

Preoperative clinical data of 121 patients with urethral stricture"

Variables Value
Age/years, ${\bar x}$ ± s 47.6±16.4
BMI/(kg/m2), ${\bar x}$ ± s 24.4±3.5
Etiology of stricture, n(%)
    Traumatic 60 (49.6)
    Iatrogenic 18 (14.9)
    Inflammatory 35 (28.9)
    Idiopathic 8 (6.6)
Location of stricture, n (%)
    Anterior urethra 57 (47.1)
    Posterior urethra 64 (52.9)
Length of stricture/cm, M (P25, P75) 3.0 (2.0, 5.5)
Time of stricture/month, M (P25, P75) 10 (5, 36)
Diabetes, n (%)
    Yes 18 (14.9)
    No 103 (85.1)
Indwelling catheter, n (%)
    Yes 78 (64.5)
    No 43 (35.5)
Urine culture, n (%)
    Positive 81 (33.1)
    Negative 40 (66.9)
Antibiotics application, n (%)
    Unused 51 (42.1)
    Time ≤ 7 d 32 (26.5)
    Time > 7 d 38 (31.4)

Table 2

Constituent ratios of the pathogens cultured from the urine specimens"

Pathogenic bacteria Strains, n Constituent ratio/%
Gram negative bacteria 63 62.4
    Escherichia coli 27 26.7
    Pseudomonas aeruginosa 7 6.9
    Klebsiella pneumoniae 4 3.9
    Acinetobacter baumannii 6 5.9
    Serratia proteamaculans 2 2.0
    Serratia liquefaciens 3 3.0
    Serratia marcescens 2 2.0
    Klebsiella aerogenes 2 2.0
    Proteus mirabilis 2 2.0
    Citrobacter freundii 1 1.0
    Citrobacter braque 1 1.0
    Providencia alcalifaciens 1 1.0
    Stenotrophomonas maltophilia 1 1.0
    Morganella morganii 1 1.0
    Enterobacter aggregates 1 1.0
    Aeromonas hydrophila 1 1.0
    Corynebacterium striatum 1 1.0
Gram positive bacteria 32 31.7
    Staphylococcus epidermidis 14 13.9
    Enterococcus faecalis 7 6.9
    Staphylococcus haemolyticus 2 2.0
    Staphylococcus aureus 2 2.0
    Enterococcus faecium 3 3.0
    Staphylococcus hominis 2 2.0
    Streptococcus agalactiae 1 1.0
    Staphylococcus saprophyticus 1 1.0
Fungi 6 5.9
    Candida glabrata 3 3.0
    Candida parapsilosis 1 1.0
    Candida albicans 1 1.0
    Candida guilliermondii 1 1.0

Table 3

Univariate analysis of the preoperative bacteriuria in 121 patients with urethral stricture"

Variables Urine culture χ2/Z/t P
Positive Negative
Age/years, ${\bar x}$ ± s 50.7±15.5 41.4±16.7 3.043 0.003
BMI/(kg/m2), ${\bar x}$ ± s 24.6±3.6 24.0±3.2 0.942 0.348
Etiology of stricture, n (%) 1.497 0.683
    Traumatic 41 (68.3) 19 (31.7)
    Iatrogenic 10 (55.6) 8 (44.4)
    Inflammatory 25 (71.4) 10 (28.6)
    Idiopathic 5 (62.5) 3 (37.5)
Location of stricture, n (%) 0.201 0.654
    Anterior urethra 37 (64.9) 20 (35.1)
    Posterior urethra 44 (68.8) 20 (31.3)
Length of stricture/cm, M (P25, P75) 3.0 (2.0, 8.0) 3.0 (2.5, 4.0) 0.768 0.432
Time of stricture /month, M (P25, P75) 10.0 (4.5, 36.0) 10.0 (5.0, 36.0) 0.000 >0.999
Diabetes, n (%) 4.602 0.032
    Yes 16 (88.9) 2 (11.1)
    No 65 (63.1) 38 (36.9)
Indwelling catheter, n (%) 15.609 <0.001
    Yes 62 (79.5) 16 (20.5)
    No 19 (44.2) 24 (55.8)
Antibiotics application, n (%) 2.312 0.315
    Unused 38 (25.5) 13 (74.5)
    Time ≤ 7 d 20 (62.5) 12 (37.5)
    Time > 7 d 23 (60.5) 15 (39.5)

Table 4

Univariate analysis of ABU and UTI in 81 patients with preoperative bacteriuria"

Variables Bacteriuria χ2/Z/t P
ABU UTI
Age/years, ${\bar x}$ ± s 49.7±15.9 52.9±14.6 0.871 0.386
BMI/(kg/m2), ${\bar x}$ ± s 24.1±3.8 25.6±3.3 1.704 0.092
Etiology of stricture, n (%) 4.034 0.250
    Traumatic 30 (73.2) 11 (26.8)
    Iatrogenic 8 (80.0) 2 (20.0)
    Inflammatory 13 (52.0) 12 (48.0)
    Idiopathic 3 (60.0) 2 (40.0)
Location of stricture, n (%) 3.010 0.083
    Anterior urethra 21 (56.8) 16 (43.2)
    Posterior urethra 33 (75.0) 11 (25.0)
Length of stricture/cm, M (P25, P75) 3.0 (2.0, 6.0) 4.5 (2.0, 10.0) 0.832 0.406
Time of stricture /month, M (P25, P75) 8 (4, 39) 11 (6, 36) 0.653 0.513
Diabetes, n (%) 0.039 0.844
    Yes 11 (68.8) 5 (31.3)
    No 43 (66.2) 22 (33.8)
Indwelling catheter, n (%) 0.138 0.711
    Yes 42 (67.7) 20 (32.3)
    No 12 (63.2) 7 (36.8)
Antibiotics application, n (%) 0.500 0.779
    Unused 26 (68.4) 12 (31.6)
    Time ≤ 7 d 14 (70.0) 6 (30.0)
    Time > 7 d 14 (60.9) 9 (39.1)

Table 5

Multivariate Logistic analysis of the preoperative bacteriuria in 121 patients with urethral stricture"

Variables OR 95%CI P
Age 1.026 0.999-1.053 0.057
Diabetes (yes) 2.933 0.582-14.787 0.192
Indwelling catheter (yes) 4.269 1.834-9.935 0.001
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