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Journal of Peking University (Health Sciences) ›› 2023, Vol. 55 ›› Issue (5): 948-952. doi: 10.19723/j.issn.1671-167X.2023.05.027

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聪 田,军 刘,波 杨,佳佳 乔,晓波 黄,清泉 许*()   

  • Received:2023-02-22 Online:2023-10-18 Published:2023-10-09
  • Contact: 清泉 许 E-mail:xuqingquan@bjmu.edu.cn
  • Supported by:
    the Beijing Health Technologies Promotion Program(BHTPP2022082)

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CLC Number: 

  • R737.11

Table 1

Clinical characteristics of patients undergoing mucosal biopsy"

Clinical characteristics Male (n=40) Female (n=29)
Urine white blood cell/(/μL), M (P25, P75) 97.50 (26.00, 912.50) 552.00 (85.50, 1 585.50)
Urine red blood cell/(/μL), M (P25, P75) 61.50 (11.25, 397.50) 30.00 (15.00, 80.00)
Urine bacterial count/(/μL), M (P25, P75) 24.00 (8.00, 622.00) 586.00 (46.00, 3 254.00)
Urine pH, M (P25, P75) 6.00 (5.63, 6.88) 6.25 (6.00, 6.50)
Urine nitrite positive, n (%) 6 (15.00) 8 (27.60)
Serum creatinine/(μmol/L), M (P25, P75) 85.00 (73.00, 102.25) 84.00 (59.50, 179.00)
Urine bacterial culture positive, n (%) 8 (20.70) 16 (58.60)
Maximum stone diameter/cm, M (P25, P75) 2.30 (2.00, 3.62) 3.00 (2.00, 4.05)
Degree of hydronephrosis, n (%)
    Mild 9 (22.50) 7 (24.10)
    Moderate 11 (27.50) 7 (24.10)
    Severe 13 (32.50) 11 (37.90)
Ipsilateral surgery, n (%) 8 (20.00) 10 (34.50)
History of stones/months, M (P25, P75) 30.00 (2.00, 120.00) 67.00 (6.75, 177.00)

Figure 1

Preoperative CT imaging of patients with renal pelvis cancer"

Table 2

Clinical characteristics of patients with renal pelvic carcinoma"

Gender Age/ years History of stones/year Degree of hydronephrosis Ipsilateral surgery Urinary infection Stone type Biopsy pathology Treatment Follow-up
Male 65 1 Mild+renal cyst Yes No Multiple Papillary high-grade UTUC Endoscopic resection Male0
Female 40 10 Severe Yes Yes Staghorn High-grade UTUC Neoadjuvant chemotherapy (GC) and RNU Female0
Male 67 20 NA No No Staghorn High-grade UTUC with squamous differentiation Endoscopic ablation and neoadjuvant chemotherapy (GC) Male0
Male 56 3 Severe Yes Yes Multiple Squamous cell carcinoma Renal artery embolization Male0
Male 50 3 Severe Yes Yes Multiple Low-grade UTUC RNU and adjuvant chemotherapy (GC) Male0
Female 68 20 Moderate Yes Yes Staghorn Low-grade UTUC with high grade component Endoscopic resection Female0
Male 58 0.25 Severe No No Multiple Low-grade UTUC with high grade component RNU Male0
Male 79 0.25 Severe+renal cyst Yes Yes Multiple UTUC Renal artery embolization Male0
1 Green DA , Rink M , Xylinas E , et al. Urothelial carcinoma of the bladder and the upper tract: Disparate twins[J]. J Urol, 2013, 189 (4): 1214- 1221.
doi: 10.1016/j.juro.2012.05.079
2 Favaretto RL , Shariat SF , Chade DC , et al. The effect of tumor location on prognosis in patients treated with radical nephrourete-rectomy at Memorial Sloan-Kettering Cancer Center[J]. Eur Urol, 2010, 58 (4): 574- 580.
doi: 10.1016/j.eururo.2010.07.003
3 Geraghty RM , Davis NF , Tzelves L , et al. Best practice in interventional management of urolithiasis: An update from the European Association of Urology Guidelines Panel for Urolithiasis 2022[J]. Eur Urol Focus, 2023, 9 (1): 199- 208.
doi: 10.1016/j.euf.2022.06.014
4 毛厚平, 施祝贤, 江涛, 等. 肾积水程度对微创经皮肾镜取石术效率及结石清除率的影响[J]. 泌尿外科杂志(电子版), 2021, 13 (3): 25- 32.
doi: 10.3969/j.issn.1674-7410.2021.03.007
5 Raghavendran M , Rastogi A , Dubey D , et al. Stones associated renal pelvic malignancies[J]. Indian J Cancer, 2003, 40 (3): 108- 112.
doi: 10.4103/0019-509X.13061
6 Paonessa J , Beck H , Cook S . Squamous cell carcinoma of the renal pelvis associated with kidney stones: A case report[J]. Med Oncol, 2011, 28 (Suppl 1): S392- S394.
7 Xiao J , Lei J , He L , et al. Renal calculus complicated with squamous cell carcinoma of renal pelvis: Report of two cases[J]. Can Urol Assoc J, 2015, 9 (5/6): E310- E312.
8 Hosseinzadeh M , Mohammadzadeh S . Primary pure squamous cell carcinoma of kidney associated with multiple stag horn stones[J]. Int Med Case Rep J, 2020, 13, 261- 263.
doi: 10.2147/IMCRJ.S261022
9 Kasahara R , Kawahara T , Tajiri R , et al. Renal squamous cell carcinoma with staghorn calculus[J]. Case Rep Oncol, 2020, 13 (1): 403- 407.
doi: 10.1159/000506675
10 Sivaramakrishna B , Aron M , Ansari MS , et al. Squamous cell carcinoma of the renal pelvis manifesting after percutaneous nephrolithotomy for long standing calculus[J]. Int Urol Nephrol, 2004, 36 (2): 149- 151.
doi: 10.1023/B:UROL.0000034672.68658.fa
11 仲浩舟, 谢汶桂, 黄玉华, 等. 肾结石合并肾盂癌的诊断和治疗[J]. 现代泌尿生殖肿瘤杂志, 2020, 12 (6): 328- 330.
doi: 10.3870/j.issn.1674-4624.2020.06.003
12 王黎, 姚启盛, 陈从波, 等. 肾结石并肾盂鳞癌六例[J]. 临床外科杂志, 2021, 29 (8): 764- 766.
doi: 10.3969/j.issn.1005-6483.2021.08.020
13 陶维雄, 李辉明, 魏世平, 等. 肾结石合并肾盂鳞状细胞癌4例报告并文献复习[J]. 临床泌尿外科杂志, 2014, 29 (7): 629- 630.
doi: 10.13201/j.issn.1001-1420.2014.07.022
14 van de Pol JAA , van den Brandt PA , Schouten LJ . Kidney stones and the risk of renal cell carcinoma and upper tract urothelial carcinoma: The Netherlands Cohort Study[J]. Br J Cancer, 2019, 120 (3): 368- 374.
doi: 10.1038/s41416-018-0356-7
15 Federico A , Morgillo F , Tuccillo C , et al. Chronic inflammation and oxidative stress in human carcinogenesis[J]. Int J Cancer, 2007, 121 (11): 2381- 2386.
doi: 10.1002/ijc.23192
16 Manganelli A , Barbanti G , Fornaini M , et al. Transitional cell carcinoma of the ureteral stump 13 years after nephrectomy for benign disease[J]. Urol Int, 1996, 56 (1): 52- 54.
doi: 10.1159/000282810
17 王爱香, 畅继武, 张淑敏, 等. 肾源性腺瘤临床病理学分析[J]. 中华泌尿外科杂志, 2011, 32 (3): 185- 188.
doi: 10.3760/cma.j.issn.1000-6702.2011.03.013
18 Nakamoto T , Igawa M , Fukushima M , et al. Fibroepithelial polyp in the renal pelvis[J]. Urol Int, 1996, 56 (1): 48- 51.
doi: 10.1159/000282809
19 叶楠, 古宏兵, 程宗三, 等. 肾结石并发肾盂癌的诊治体会[J]. 国际泌尿系统杂志, 2020, 40 (3): 534- 537.
doi: 10.3760/cma.j.cn431460-20190401-00039
20 Yeh CC , Lin TH , Wu HC , et al. A high association of upper urinary tract transitional cell carcinoma with nonfunctioning kidney caused by stone disease in Taiwan[J]. Urol Int, 2007, 79 (1): 19- 23.
doi: 10.1159/000102907
21 赖斌, 赵勇, 冯峰, 等. 尿脱落细胞的荧光原位杂交技术在尿路上皮癌的临床应用研究[J]. 泌尿外科杂志(电子版), 2020, 12 (2): 31- 36.
doi: 10.3969/j.issn.1674-7410.2020.02.007
22 于潇, 金讯波, 夏庆华, 等. 肾盂癌行输尿管软镜检查的临床意义[J]. 泌尿外科杂志(电子版), 2013, 5 (2): 50- 51.
23 Seisen T , Peyronnet B , Dominguez-Escrig JL , et al. Oncologic outcomes of kidney-sparing surgery versus radical nephroureterectomy for upper tract urothelial carcinoma: A systematic review by the EAU non-muscle invasive bladder cancer guidelines panel[J]. Eur Urol, 2016, 70 (6): 1052- 1068.
doi: 10.1016/j.eururo.2016.07.014
24 Birtle A , Johnson M , Chester J , et al. Adjuvant chemotherapy in upper tract urothelial carcinoma (the POUT trial): A phase 3, open-label, randomised controlled trial[J]. Lancet, 2020, 395 (10232): 1268- 1277.
doi: 10.1016/S0140-6736(20)30415-3
25 Leow JJ , Chong YL , Chang SL , et al. Neoadjuvant and adjuvant chemotherapy for upper tract urothelial carcinoma: A 2020 syste-matic review and meta-analysis, and future perspectives on syste-mic therapy[J]. Eur Urol, 2021, 79 (5): 635- 654.
doi: 10.1016/j.eururo.2020.07.003
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