Journal of Peking University(Health Sciences) >
Short-term effects and seasonal variation of ozone on daily hospital outpatient visits for childhood asthma in Lanzhou
Received date: 2020-06-08
Online published: 2022-04-13
Supported by
Research Fund Project of Gansu Provincial Hospital(18GSSY4-24)
Objective: To analyze the effects of ozone (O3) concentrations measured with different approaches across different seasons on the total number of childhood asthma-related clinical visits, as well as the differentiation of such effects across different groups of patients. Methods: The outpatient data of three grade A tertiary hospitals in Lanzhou City spanning from 1 January 2014 to 31 December 2017, as well as air pollution and meteorological data during the same period were collected. Considering the nonlinear relationship between O3 concentrations and the total number of childhood asthma-related clinical visits and meteorological factors, a generalized additive temporal sequence model was employed to analyze the short-term association between changes in O3 concentrations and the total number of childhood asthma-related clinical visits. Taking into account of the variations in O3 concentrations within 1 day, this study adopted different measurement approaches to address the three types of O3 exposures, namely, the maximum 1 h daily concentration (O3max1h), the maximum 8 h daily concentration (O38h) and the mean 24 h daily concentration (O324h) as the short term exposure indicators to O3, followed by a model-based analysis. Results: The increase in short-term exposure levels to O3 in summer had a significant effect on the increase in the total number of childhood asthma-related clinical visits. With lag0 for the current day, every 10 μg/m3 increase in atmospheric concentration of O3max1h was associated with an increase in the total number of childhood asthma-related clinical visits by 3.351% (95%CI: 1.231%-5.516%); for every 10 μg/m3 increase in O38h concentration, the total number of childhood asthma-related clinical visits increased by 3.320% (95%CI: 0.197%-3.829%); for every 10 μg/m3increase in O324h concentration, the total number of childhood asthma-related clinical visits in summer increased by 6.600% (95%CI: 0.914%-12.607%); moreover, an increase in exposure to O3max1h also led to a significant rise in the total number of childhood asthma-related clinical visits among the males. Conclusion: The increase in short-term exposure levels to O3 in summer in Lanzhou City has a significant effect on the increase in the total number of childhood asthma-related clinical visits; O3max1h is more closely correlated with the increase in the total number of childhood asthma-related clinical visits.
Key words： Ozone; Air pollutants; Child; Asthma; Outpatients
Hong ZHANG , Ji-yuan DONG , Jian-jun WANG , Lin-xia FAN , Qiang QU , Yang LIU . Short-term effects and seasonal variation of ozone on daily hospital outpatient visits for childhood asthma in Lanzhou[J]. Journal of Peking University(Health Sciences), 2022 , 54(2) : 227 -235 . DOI: 10.19723/j.issn.1671-167X.2022.02.005
| [1] | 徐甜, 王志远, 张兵, 等. 中国环境保护重点城市空气质量指数时空变化特征[J]. 中国公共卫生, 2016, 32(8):1027-1031. |
| [2] | Ferrante G, Antona R, Malizia V, et al. Asthma and air pollution[J]. Ital J Pediatr, 2014, 40(S1):A75. |
| [3] | Zhang YW, Ni H, Bai LJ, et al. The short-term association between air pollution and childhood asthma hospital admissions in urban areas of Hefei City in China: A time-series study[J]. Environ Pollut, 2019, 169:510-516. |
| [4] | Ding L, Zhu DJ, Peng DH, et al. Air pollution and asthma attacks in children: A case-crossover analysis in the city of Chongqing, China[J]. Environ Pollut, 2017, 220(PtA):348-353. |
| [5] | Dai YR, Qiu H, Sun SZ, et al. Age-dependent effect of ambient ozone on emergency asthma hospitalizations in Hong Kong[J]. J Allergy Clin Immun, 2018, 141(4):1532-1534. |
| [6] | 杨春雪. 细颗粒物和臭氧对我国居民死亡影响的急性效应研究[D]. 上海: 复旦大学, 2012. |
| [7] | 闫美霖. 广州市越秀区臭氧短期暴露与人群死亡风险的时间序列研究及健康风险评估[D]. 北京: 北京大学, 2013. |
| [8] | 尹伊. 基于CMAQ模式、MEIC清单对兰州市主城区臭氧污染特征的初步研究[D]. 兰州: 兰州大学, 2019. |
| [9] | Ko FWS, Tam W, Wong TW, et al. Effects of air pollution on asthma hospitalization rates in different age groups in Hong Kong[J]. Clin Exp Allergy, 2007, 37(9):1312-1319. |
| [10] | 班婕, 李湉湉. 北京市不同度量方式下臭氧短期暴露人群急性健康效应研究[J]. 环境与健康杂志, 2016, 33(4):287-291. |
| [11] | Capraz O, Deniz A, Dogan N, et al. Effects of air pollution on respiratory hospital admissions in Istanbul, Turkey, 2013 to 2015[J]. Chemosphere, 2017, 181:544-550. |
| [12] | Chang Q, Liu S, Chen ZJ, et al. Association between air pollutants and outpatient and emergency hospital visits for childhood asthma in Shenyang City of China[J]. Int J Biometeorol, 2020, 64(9):1539-1548. |
| [13] | Lee JT, Cho YS, Son JY. Relationship between ambient ozone concentrations and daily hospital admissions for childhood asthma/atopic dermatitis in two cities of Korea during 2004-2005[J]. Int J Environ Health Res, 2010, 20(1):1-11. |
| [14] | Petroeschevsky A, Simpson RW, Thalib L, et al. Associations between outdoor air pollution and hospital admissions in Brisbane, Australia[J]. Arch Environ Health, 2001, 56(1):37-52. |
| [15] | Li TT, Yan ML, Ma WJ, et al. Short-term effects of multiple ozone metrics on daily mortality in a megacity of China[J]. Environ Sci Pollut Res Int, 2015, 22(11):8738-8746. |
| [16] | Yang CX, Yang HB, Guo S, et al. Alternative ozone metrics and daily mortality in Suzhou: The China Air Pollution and Health Effects Study (CAPES)[J]. Sci Total Environ, 2012, 426:83-89. |
| [17] | 刘金悦. 济南市大气污染与儿童呼吸系统疾病住院量的相关性分析[D]. 济南: 济南大学, 2019. |
| [18] | 陈浪. 石家庄市空气污染对儿童呼吸系统疾病门诊影响及温度的修饰效应[D]. 石家庄: 华北理工大学, 2019. |
| [19] | 马依拉·尔肯. 乌鲁木齐市大气污染物,气象因素与儿童哮喘住院人数的相关研究[D]. 乌鲁木齐: 新疆医科大学, 2014. |
/
| 〈 |
|
〉 |