Abstract: Objective：To evaluate the effectiveness of conducting multiple arthroplasty to treat multiple joints disease in terms of quality of life (QOL) and function improvement. Methods:We compared our results with the reported results of single and dual arthroplasty to see if there is any improvement in QOL, functional scores or complications. In this study, 13 patients admitted to Department of Adult Reconstructive Surgery, Beijing Jishuitan hospital from 2005 to 2009 were included. Questionnaires SF-36 were used to evaluate the QOL. Harris hip score, American Knee Society Score (KSS) were used to evaluate the joint function. The patients were evaluated before surgery to the latest follow up. Results:SF-36 has changed as follow: physical function 4.17±14.43→65.83±24.76,  role physical 25.00±26.11→60.42±45.8, bodily pain 23.83±21.41→76.88±20.89, general health 53.33±33.87→76.67±14.67, vitality 50.42±17.25→71.67±16.28, social functioning 29.17±33.50→73.96±33.90, role emotional 22.08±35.61→77.77±41.03, mental health 53.33±25.70→82.67±14.41, which indicated that they all improved greatly after the surgery (P<0.05). Harris score increased from 37.68±14.71 before the surgery to 83.36±13.54 after the surgery. KSS has also showed sharp improvement (P<0.001) in both clinical score (42.52±23.83→77.74±20.67) and function score (-2.61±22.56→65.65±30.76).Conclusion:Multiple arthroplasty is one of the most effective methods which can markedly improve the quality of life in patients with multiple joints disease. But complications are common and joint functions are relatively poor.

Key words: Arthroplasty, replacement, hip, Arthroplasty, replacement, knee, Quality of life