Journal of Peking University (Health Sciences) ›› 2023, Vol. 55 ›› Issue (2): 210-216. doi: 10.19723/j.issn.1671-167X.2023.02.003

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波 张*()   

  • Received:2022-10-17 Online:2023-04-18 Published:2023-04-12
  • Contact: 波 张 E-mail:zhangbo@bjmu.edu.cn

RICH HTML

  

CLC Number: 

  • R739.4

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神经内分泌肿瘤 分级 诊断标准
胃肠、胰腺、胆道
  NET NET, G1 < 2 mitoses/2 mm2和/或Ki-67 < 3%
NET, G2 2~20 mitoses/2 mm2和/或Ki-67 3%~20%
NET, G3,无NEC组织学特点 >20 mitoses/2 mm2和/或Ki-67>20%
  NEC Small cell NEC(小细胞特征) >20 mitoses/2 mm2和/或Ki-67>20% (often>70%), 小细胞特征
Large cell NEC(大细胞特征) >20 mitoses/2 mm2和/或Ki-67>20% (often>70%), 大细胞特征
上呼吸道、涎腺
  NET NET, G1 < 2 mitoses/2 mm2,无坏死, Ki-67 < 20%
NET, G2 2~10 mitoses/2 mm2和/或坏死,Ki-67 < 20%
NET, G3,无NEC组织学特点 >10 mitoses/2 mm2和/或Ki-67>20%
  NEC Small cell NEC(小细胞特征) >10 mitoses/2 mm2和/或Ki-67>20% (often>70%)
Large cell NEC(大细胞特征) >10 mitoses/2 mm2,和/或Ki-67>20% (often>55%)
肺、胸腺
  NET 典型类癌/NET, G1 < 2 mitoses/2 mm2,无坏死
非典型类癌/NET, G2 2~10 mitoses/2 mm2,坏死(点状)
  NEC Small cell (lung) carcinoma(小细胞特征) >10 mitoses/2 mm2, 坏死,Ki-67(often>70%),小细胞特征
Large cell NEC(大细胞特征)
*具有高增殖活性非典型类癌
>10 mitoses/2 mm2, 坏死,Ki-67>20%(often>40%),大细胞特征
*非典型类癌组织学,higher (>10 mitoses/2 mm2)
mitotic count和/或higher (>30%) Ki-67

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