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Journal of Peking University(Health Sciences) ›› 2019, Vol. 51 ›› Issue (4): 728-732. doi: 10.19723/j.issn.1671-167X.2019.04.023

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Biomechanical changes of sheep cervical spine after unilateral hemilaminectomy and different degrees of facetectomy

Chao WU1,Zhen-yu WANG1,△(),Guo-zhong LIN1,△(),Tao YU1,Bin LIU1,Yu SI1,Yi-bo ZHANG1,Yuan-chao LI2   

  1. 1.Department of Neurosurgery,Peking University Third Hospital,Beijing 100191,China
    2. School of Mechanical Engineering,Shanghai Jiao Tong University, Shanghai 200240,China
  • Received:2018-03-21 Online:2019-08-18 Published:2019-09-03
  • Contact: Zhen-yu WANG,Guo-zhong LIN E-mail:wzyu502@126.com;leenho@163.com
  • Supported by:
    Supported by the National Natural Science Foundation of China(81441044);the Natural Science Foundation of Beijing(7144253)

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Abstract:

Objective: To establish animal models and investigate the impact of unilateral hemilaminectomy(ULHL) and different degrees of facetectomy (FT) on the cervical spinal biomechanics.Methods: Twenty sheep were randomly and evenly divided into 4 groups. No operation was performed for group A, right C4-C6 ULHL was performed for group B, right C4-C6 ULHL and 50% ipsilateral C4-C5 FT was performed for group C, right C4-C6 ULHL and 100% ipsilateral C4-C5 FT was performed for group D. Animals of group A, B, C and D were sacrificed 24 weeks after operating and fresh cervical spine specimens were acquired, biomechanically tested and these data were compared to determine whether ULHL and different degrees of FT led to long-term differences in range of motion.Results: (1) Changes of the total range of motion of cervical spine 24 weeks after surgery: the total range of motion of group D (60.2°±8.6°) was significantly greater than group A (40.7°±6.4°) and group B (41.2°±13.1°) under flexion-extension station,the total range of motion of group D (81.5°±15.7°) was significantly greater than that of group A (56.7°±12.2°) and group B (57.7°±12.8°) under lateral bending station,and the total range of motion of group D (38.5°±17.5°) had no obvious increase compared with group A (26.4°±9.9°) and group B (27.1°±10.9°) under axial rotation station. The total range of motion of group C had no obvious increase compared with group A and group B under flexion-extension station (44.1°±11.7°), lateral bending station (73.6°±11.4°) and axial rotation station (31.3°±11.5°). (2) Changes of the intersegmental motion 24 weeks after surgery: the intersegmental motion of group D (20.3°±4.6°) at C4-C5 was significantly greater than that of group A (11.7°±3.4°) and group B (11.9°±2.1°) under flexion-extension station, the intersegmental motion of group D (26.8°±3.5°) at C4-C5 was significantly greater than that of group A (15.2°±3.1°) and group B (16.2°±3.2°) under lateral bending station, the intersegmental motion of group D (15.2°±3.5°) at C4-C5 was significantly greater than that of group A (6.6°±2.3°) and group B (7.1°±1.9°) under axial rotation station. The intersegmental motion of group C (21.2°±4.1°) at C4-C5 was significantly greater than that of group A and group B under lateral bending station, the intersegmental motion of group C at C4-C5 had no obvious increase compared with group A and group B under flexion-extension station (15.7°±3.7°) and axial rotation station (10.3°±3.1°).Conclusion: ULHL does not affect cervical stability, ULHL and 50% ipsilateral FT does not affect the long-term cervical stability, ULHL and 100% ipsilateral FT can lead to long-term instability under lateral bending and flexion-extension station.

Key words: Cervical spine, Hemilaminectomy, Facetectomy, Biomechanics

CLC Number: 

  • R681.5

Table 1

Total range of motion of cervical spine 24 weeks after surgery in different groups/(°)"

Group Group A Group B Group C Group D F value P value
Flexion-extension 40.7±6.4 41.2±13.1 44.1±11.7 60.2±8.6*# 4.026 0.03
Lateral bending 56.7±12.2 57.7±12.8 73.6±11.4 81.5±15.7*# 4.314 0.02
Axial rotation 26.4±9.9 27.1±10.9 31.3±11.5 38.5±17.5 0.941 0.44

Table 2

C3-C4 intersegmental motion of cervical spine 24 weeks after surgery in different groups/(°)"

Group Group A Group B Group C Group D F value P value
Flexion-extension 7.1±2.1 7.3±3.1 7.6±1.7 8.0±2.6 0.129 0.94
Lateral bending 12.3±2.3 12.7±2.6 16.3±4.3 18.5±5.7 2.806 0.07
Axial rotation 7.2±2.4 7.5±2.2 8.3±2.1 9.6±2.7 1.033 0.41

Table 3

C4-C5 intersegmental motionof cervical spine 24 weeks after surgery in different groups/(°)"

Group Group A Group B Group C Group D F value P value
Flexion-extension 11.7±3.4 11.9±2.1 15.7±3.7 20.3±4.6*# 6.433 0.005
Lateral bending 15.2±3.1 16.2±3.2 21.2±4.1*# 26.8±3.5*# 11.594 0.001
Axial rotation 6.6±2.3 7.1±1.9 10.3±3.1 15.2±3.5*# 10.072 0.001

Table 4

C5-C6 intersegmental motion of cervical spine 24 weeks after surgery in different groups/(°)"

Group Group A Group B Group C Group D F value P value
Flexion-extension 12.7±2.4 13.2±3.1 13.4±2.7 15.2±3.6 0.667 0.58
Lateral bending 15.7±3.2 17.3±2.8 19.6±3.4 20.5±3.1 2.428 0.10
Axial rotation 7.1±2.6 7.3±3.1 9.3±2.5 11.5±3.5 2.425 0.10

Table 5

C6-C7 intersegmental motion of cervical spine 24 weeks after surgery in different groups/(°)"

Group Group A Group B Group C Group D F value P value
Flexion-extension 10.0±2.4 11.2±2.7 12.1±2.7 14.3±2.5 2.482 0.098
Lateral bending 15.1±2.2 17.5±2.6 18.6±3.4 19.5±2.7 2.374 0.109
Axial rotation 5.7±2.1 6.1±2.3 8.2±2.5 8.9±2.4 2.260 0.124
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