Journal of Peking University (Health Sciences) ›› 2021, Vol. 53 ›› Issue (3): 628-631. doi: 10.19723/j.issn.1671-167X.2021.03.032

Previous Articles    

  

  • Received:2019-05-14 Online:2021-06-18 Published:2021-06-16

CLC Number: 

  • R734.2

Table 1

452 Patients’ Clinicopathological Features"

Variables n (%)
Gender
Male 199 (44.0)
Female 253 (56.0)
Age/years
<65 289 (63.9)
≥65 163 (36.1)
Nodule number
Solitary 169 (37.4)
Multiple 283 (62.6)
Nodule type
GGO 100 (22.1)
pSN 42 (9.3)
SN 248 (54.9)
N/A 62 (13.7)
Nodule location
Right upper lobe 71 (15.7)
Right middle lobe 32 (7.1)
Right lower lobe 54 (11.9)
Left upper lobe 49 (10.8)
Left lower lobe 35 (7.7)
Multi-lobe 211 (46.7)
Nodule size/mm, $\bar{x} \pm s$ 7.54±4.65
Histopathological type
Benign lesions 10 (21.7)
Preinvasive lesions 4 (8.7)
AAH 3 (6.5)
AIS 1 (2.2)
MIA 2 (4.3)
IA 24 (52.2)
Other 6 (13.0)

Table 2

Implementation of pulmonary nodules MDT recommendations"

Management option Recommendation Unimplemented ratio, n(%)
Radiologic study 398 36 (9.0)
CT guided biopsy 22 14 (63.6)
Treatment
Surgery 52 21 (40.4)
Radiotherapy 4 4 (100)

Table 3

MDT and pathological diagnosis of pulmonary nodules"

Pathologic diagnosis MDT diagnosis Total
Benign nodule Malignant nodule
Benign nodule 2 3 5
Malignant nodule 2 32 34
Total 4 35 39

Figure 1

Misdiagnosed case 1: CT scan of a part solid nodule in the right middle lobar"

Figure 2

Misdiagnosed case 2: CT scan of a part solid nodule in the right upper lobar"

Figure 3

Misdiagnosed case 3: CT scan of a part solid nodule in the left upper lobar"

[1] Freeman RK, Van Woerkom JM, Vyverberg A, et al. The effect of a multidisciplinary thoracic malignancy conference on the treatment of patients with lung cancer[J]. Eur J Cardiothorac Surg, 2010,38(1):1-5.
doi: 10.1016/j.ejcts.2010.01.051
[2] Denton E, Conron M. Improving outcomes in lung cancer: the value of the multidisciplinary health care team[J]. J Multidiscip Healthc, 2016,9:137-144.
doi: 10.2147/JMDH.S76762 pmid: 27099511
[3] MacMahon H, Naidich DP, Goo JM, et al. Guidelines for management of incidental pulmonary nodules detected on ct images: from the fleischner society 2017[J]. Radiology, 2017,284(1):228-243.
doi: 10.1148/radiol.2017161659 pmid: 28240562
[4] Huang P, Park S, Yan R, et al. Added value of computer-aided CT image features for early lung cancer diagnosis with small pulmonary nodules: a matched case-control study[J]. Radiology, 2018,286(1):286-295.
doi: 10.1148/radiol.2017162725 pmid: 28872442
[5] Hou S, Lin X, Wang S, et al. Combination of positron emission tomography/computed tomography and chest thin-layer high-resolution computed tomography for evaluation of pulmonary nodules: correlation with imaging features, maximum standardized uptake value, and pathology[J]. Medicine (Baltimore), 2018,97(31):e11640.
doi: 10.1097/MD.0000000000011640
[6] Gao F, Ge X, Li M, et al. CT features of lung scar cancer[J]. J Thorac Dis, 2015,7(3):273-280.
[7] Baldwin DR, Callister ME. The British Thoracic Society guidelines on the investigation and management of pulmonary nodules[J]. Thorax, 2015,70(8):794-798.
doi: 10.1136/thoraxjnl-2015-207221 pmid: 26135833
[8] Yang W, Sun Y, Fang W, et al. High-resolution computed tomography features distinguishing benign and malignant lesions manifesting as persistent solitary subsolid nodules[J]. Clin Lung Cancer, 2018,19(1):e75-e83.
doi: 10.1016/j.cllc.2017.05.023
[9] Lee HY, Choi YL, Lee KS, et al. Pure ground-glass opacity neoplastic lung nodules: histopathology, imaging, and management[J]. AJR Am J Roentgenol, 2014,202(3):W224-233.
doi: 10.2214/AJR.13.11819
[10] van Riel SJ, Sánchez CI, Bankier AA, et al. Observer variability for classification of pulmonary nodules on low-dose CT images and its effect on nodule management[J]. Radiology, 2015,277(3):863-871.
doi: 10.1148/radiol.2015142700
[1] LIAO Xu-he,WANG Rong-fu,LIU Meng,CHEN Xue-qi,XIONG Yan,NONG Lin,YIN Lei,ZHANG Bing-ye,DU Yu-jing. Semiquantitative parameters of 18F-FDG PET/CT, gene mutation states of epidermal growth factor receptor and anaplastic lymphoma kinase in prognosis evaluation of patients with lung adenocarcinoma [J]. Journal of Peking University (Health Sciences), 2021, 53(2): 246-254.
[2] Yi BAO,Juan-fen MO. Concordant point mutation of ETS-related gene (ERG) in tumor tissues from a synchronous multiple primary lung cancer: A case report [J]. Journal of Peking University (Health Sciences), 2020, 52(5): 971-974.
[3] Qiao ZHU,Cui REN,Yan ZHANG,Mei-jiao LI,Xiao-hua WANG. Comparative imaging study of mediastinal lymph node from pre-surgery dual energy CT versus post-surgeron verifications in non-small cell lung cancer patients [J]. Journal of Peking University (Health Sciences), 2020, 52(4): 730-737.
[4] Liang GENG,Jing LV,Jing FAN. Effect of Fei-Liu-Ping ointment combined with cyclophosphamide on lung cancer cell proliferation and acidic microenvironment [J]. Journal of Peking University (Health Sciences), 2020, 52(2): 247-253.
[5] Yu-qing OUYANG,Lian-fang NI,Xin-min LIU. Prognosis factors analysis of patients with malignant solitary pulmonary nodules [J]. Journal of Peking University(Health Sciences), 2020, 52(1): 158-162.
[6] Chun-feng ZHANG,Yun LIU,Min LU,Xiao-juan DU. Expression of hUTP14a in non-small cell lung cancer [J]. Journal of Peking University(Health Sciences), 2019, 51(1): 145-150.
[7] MEI Fang, ZHAO Ting-ting, GAO Fei, ZHENG Jie. A rare pulmonary benign bi-phasic tumor: a case report of pulmonary adenofibroma and literature review [J]. Journal of Peking University(Health Sciences), 2017, 49(6): 1076-1080.
[8] MA Xiao-mei, CAO Yan-zhen, JI Wen-li, ZHAO Feng, FANG Xin-zhi. Analysis of epidermal growth factor receptor mutations and its clinico-pathologic characteristics of the primary lung adenocarcinoma in Xinjiang Uighur Autonomous Region [J]. Journal of Peking University(Health Sciences), 2016, 48(4): 663-666.
[9] GENG Liang, FAN Jing, GAO Qi-long, YU Jing, HUA Bao-jin. Preliminary study for the roles and mechanisms of 20(R)-ginsenoside Rg3 and PEG-PLGA-Rg3 nanoparticles in the Lewis lung cancer mice [J]. Journal of Peking University(Health Sciences), 2016, 48(3): 496-501.
[10] MOU Qian-qian, YU Chun-hua, LI Jun-ying. Investigation and analysis for impact factors of distress in patients with first diagnosed lung can-cer [J]. Journal of Peking University(Health Sciences), 2016, 48(3): 507-514.
[11] CHEN Ke-Zhong, YANG Fan, WANG Xun, JIANG Guan-Chao, LI Jian-Feng, WANG Jun. A clinical prediction model for N2 lymph node metastasis in clinical stageⅠnon-small cell lung cancer [J]. Journal of Peking University(Health Sciences), 2015, 47(2): 295-301.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] . [J]. Journal of Peking University(Health Sciences), 2009, 41(4): 456 -458 .
[2] . [J]. Journal of Peking University(Health Sciences), 2009, 41(2): 125 -128 .
[3] . [J]. Journal of Peking University(Health Sciences), 2009, 41(2): 135 -140 .
[4] . [J]. Journal of Peking University(Health Sciences), 2009, 41(2): 217 -220 .
[5] . [J]. Journal of Peking University(Health Sciences), 2009, 41(1): 52 -55 .
[6] . [J]. Journal of Peking University(Health Sciences), 2009, 41(1): 109 -111 .
[7] . [J]. Journal of Peking University(Health Sciences), 2009, 41(3): 297 -301 .
[8] . [J]. Journal of Peking University(Health Sciences), 2009, 41(5): 505 -515 .
[9] . [J]. Journal of Peking University(Health Sciences), 2009, 41(5): 599 -601 .
[10] . [J]. Journal of Peking University(Health Sciences), 2009, 41(5): 516 -520 .