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Journal of Peking University (Health Sciences) ›› 2023, Vol. 55 ›› Issue (5): 857-864. doi: 10.19723/j.issn.1671-167X.2023.05.013

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Effects of delayed ureteral stents removal during the COVID-19 pandemic on the quality of life and psychological status of postoperative patients with urinary calculi

Jin-hui LAI,Qi WANG,Jia-xiang JI,Ming-rui WANG,Xin-wei TANG,Ke-xin XU,Tao XU,Hao HU*()   

  1. Department of Urology, Peking University People's Hospital, Beijing 100044, China
  • Received:2023-03-20 Online:2023-10-18 Published:2023-10-09
  • Contact: Hao HU E-mail:huhao@bjmu.edu.cn

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Abstract:

Objective: To explore the impacts of delayed ureteral stent removal on the quality of life (QoL) and mental health of urinary calculi postoperative patients due to the corona virus disease 2019(COVID-19) pandemic. Methods: The demographic and clinical data of patients with ureteral stent placement after urinary endoscopic lithotripsy and returned to Peking University People's Hospital for stent removal from December 2019 to June 2020 were collected. Ureteral stent symptoms questionnaire (USSQ) score and the outcome 20-item self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were collected to estimate the QoL and mental status. The USSQ consisted of 44 questions in 6 domains (including urinary symptom, physical pain, general health, work performance, sexual function, and ureteral stent related infection). For most questions in each domain, its score was a five-point Likert-type scale from 1 to 5, and a small proportion of questions was quantified by 1 to 4 or 1 to 7 scale. SAS and SDS both contained 20 questions used to assess a patient's level of anxiety and depression. Its scoring for each item was on a four-point Likert-type scale from 1 to 4. A total score (ranging from 20 to 80) was the main statistical indicator. The level of clinical anxiety and depression was quantified by using standard scores (total score multiplied by 1.25 to produce integers). And the multi-group structural equation model was constructed by analysis of moment structure (AMOS) analysis. Results: Overall, 71 patients were enrolled for analysis. It was found that the median duration of ureteral stent time differed significantly between the control and delayed groups for 32 (30, 33) d and 94.5 (88, 103) d, respectively. The delayed group resulted in higher scores in the USSQ multidimensional, which included urinary symptoms, general health, work performance and ureteral stent related infections. Anxiety and depression were also significantly serious in the delayed group than in the control group. A longer indwelling time of a ureteral stent could exacerbate the effects of urinary symptoms and physical pain on work performance (P=0.029 < 0.05). Among them, the patients with severe urinary symptoms leading to poor work performance were most significantly affected by prolonged ureteral stent duration time (CR=2.619>1.96). Conclusion: Patients with delayed ureteral stent removal due to the COVID-19 had resulted in worse QoL and mental status. Stents related symptoms are more severe in patients with higher anxiety and depression degree during COVID-19. To improve the QoL and mental health of patients after urinary calculi surgery during COVID-19, it is still not recommended to prolong the stent duration time or corresponding intervention measures should be taken.

Key words: Prolonged ureteral stent duration time, Quality of life (QoL), Anxiety, Depression, Corona virus disease 2019 (COVID-19)

CLC Number: 

  • R699

Table 1

Baseline characteristics of enrolled patients"

Items Control group Delayed ureteral sent removal group P
Number of patients, n(%) 35 (49.3) 36 (50.7)
Duration ureteric stent time/d, M (P25, P75) 32 (30, 33) 94.5 (88, 103) < 0.001
Gender, n(%) 0.144
    Male 27 (77.1) 22 (61.1)
    Female 8 (22.9) 14 (38.9)
Age，n(%) 0.552
    <40 12 (34.3) 8 (22.2)
    40-60 12 (34.3) 17 (47.2)
    >60 11 (31.4) 11 (30.6)
Surgery type, n(%) 0.017
    PCNL 2 (5.7) 11 (30.6)
    RIRS 23 (65.7) 20 (55.6)
    URL 10 (28.6) 5 (13.9)
Stone location, n(%) 0.275
    Left 13 (37.1) 18 (50.0)
    Right 22 (62.9) 18 (50.0)
Working status, n(%) 0.002
    Full time 16 (45.7) 9 (25.0)
    Not working or unemployed 0 (0) 10 (27.8)
    Retirement 19 (54.3) 17 (47.2)
Bed rest, n(%) 0.005
    No 35 (100.0) 28 (77.8)
    Yes 0 (0) 8 (22.2)
Rest time, n(%) 0.317
    None 20 (57.1) 25 (69.4)
    Half a day 10 (28.6) 5 (13.9)
    Two half a day 5 (14.3) 6 (16.7)

Table 2

Results of USSQ score of the patients"

Items Control group (n=35) Delayed ureteral sent removal group (n=36) P
USSQ urinary symptom score (U1－U11), M (P25, P75) 19 (18, 22) 26 (25, 27) < 0.001
USSQ physical pain score (P4－P9), M (P25, P75) 9 (7, 9) 7 (6, 11) 0.024
Overall pain score (SPDS), $\bar x \pm s$ 0.34±1.03 1.22±2.26 0.039
Number of pain sites, $\bar x \pm s$ 0.11±0.32 0.39±0.69 0.035
USSQ general health score (G1－G6), M (P25, P75) 10 (8, 11) 15 (14, 16) < 0.001
USSQ work performance score (W5－W7), M (P25, P75) 4 (3, 5) 7 (7, 8) < 0.001
USSQ sexual function score (S4+S5), $\bar x \pm s$ 1.34±1.95 1.08±1.96 0.578
Sent related sexual abstinence/%, n (%) 23 (65.7) 28 (77.8) 0.259
USSQ ureteral stent related infection (I1－I5), M (P25, P75) 7 (7, 8) 10 (9, 11) < 0.001
Total USSQ score, M (P25, P75) 52 (48, 53) 68 (65, 72) < 0.001

Table 3

Results of ureteral stent symptoms questionnaire (USSQ) sub-score of the patients"

Items Control Group Delayed ureteral sent removal group P
USSQ urinary symptom score
    U1-daytime frequency, M(P25, P75) 2 (1, 2) 3 (2, 3) < 0.001
    U2-nocturia, $\bar x \pm s$ 2.23±0.88 2.33±0.59 0.555
    U3-urgency, M(P25, P75) 1 (1, 2) 2 (1, 2) 0.001
    U4-straining to start, M(P25, P75) 1 (1, 2) 2 (1, 2) 0.002
    U5-urge incontinence, $\bar x \pm s$ 1.20±0.41 1.33±0.48 0.209
    U6-residual urine sense, M(P25, P75) 2 (1, 2) 3 (3, 4) < 0.001
    U7-dysuria, $\bar x \pm s$ 2.03±0.71 2.31±0.62 0.084
    U8-hematuria rate, M(P25, P75) 2 (1, 2) 2 (2, 3) 0.016
    U9-hematuria amount, M(P25, P75) 2 (1, 2) 2 (2, 2) 0.034
    U10-total symptom, M(P25, P75) 1 (1, 2) 2 (2, 3) < 0.001
    U11-intention of long-term indwelling stent, M(P25, P75) 3 (3, 3) 4 (3, 4) < 0.001
USSQ physical pain score
    P1-presence of pain, n(%) 4 (11.4) 10 (27.8) 0.083
    P2-presence of upper abdominal pain, n(%) 0 (0) 0 (0) -
    P3-SPDS of upper abdominal pain 0 0 -
    P2-presence of lower abdominal pain, n(%) 0 (0) 5 (13.9) 0.054
    P3-SPDS of lower abdominal pain 0 0.39±1.05 0.033
    P2-presence of suprapubic pain, n(%) 0 (0) 0 (0) -
    P3-SPDS of suprapubic pain 0 0 -
    P2-presence of back pain, n(%) 3 (8.6) 9 (25) 0.065
    P3-SPDS of back pain, $\bar x \pm s$ 0.23±0.81 0.83±1.54 0.042
    P2-presence of penis pain, n(%) 1 (2.9) 0 (0) 0.493
    P3-SPDS of penis pain, $\bar x \pm s$ 0.11±0.68 0 0.324
    P4-physical activity, $\bar x \pm s$ 1.20±0.41 1.47±0.81 0.078
    P5-sleep difficulty, M(P25, P75) 1 (1, 1) 1 (1, 2) 0.024
    P6-pain during voiding, M(P25, P75) 2 (2, 3) 1 (1, 2) 0.002
    P7-flank pain during voiding, $\bar x \pm s$ 1.51±0.51 1.44±0.50 0.562
    P8-analgesics, $\bar x \pm s$ 1.20±0.41 1.31±0.58 0.377
    P9-effects of stent-related pain, $\bar x \pm s$ 1.40±0.55 1.61±1.13 0.319
USSQ general health score
    G1-light physical activities 1 1 -
    G2-heavy physical activities, M(P25, P75) 3 (2, 3) 4 (3, 4) < 0.001
    G3-tiredness and fatigue, M(P25, P75) 1 (1, 2) 2 (2, 2) < 0.001
    G4-calm and tranquility, M(P25, P75) 1 (1, 2) 3 (3, 4) < 0.001
    G5-social activities, M(P25, P75) 1 (1, 2) 4 (3, 4) < 0.001
    G6-extra help from relatives and friends, $\bar x \pm s$ 1.60±0.50 1.72±0.45 0.284
USSQ work performance score, M(P25, P75)
    W5-shorten working hours 1 (1, 1) 2 (2, 2) < 0.001
    W6-change the usual job 1 (1, 2) 2 (1, 2) 0.002
    W7-working hours 2 (1, 3) 4 (3.75, 4) < 0.001
USSQ sexual function score, $\bar x \pm s$
    S4-dyspareunia 1.23±0.43 1.17±0.38 0.519
    S5-sexual life 2.74±0.51 2.94±0.23 0.037
USSQ ureteral stent related infection score
    I1-urinary tract infection frequency, M(P25, P75) 1 (1, 2) 2 (2, 3) < 0.001
    I2-antibiotic use, M(P25, P75) 1 (1, 1) 1 (1, 2) < 0.001
    I3-extra help from medical staff, $\bar x \pm s$ 1.14±0.36 1.25±0.44 0.262
    I4-seek medical attention, M(P25, P75) 1 (1, 1) 1 (1, 1) 0.006
    I5-intention to indwell the second stent on the opposite side, M(P25, P75) 3 (3, 4) 4 (4, 4) < 0.001

Table 4

Correlation analysis among ureteral stent symptoms questionnaire (USSQ) dimensions"

Items Urinary symptom Physical pain General health Work performance Sexual function Ureteral stent related infection
Urinary symptom 1
Physical pain -0.120 1
General health 0.626# 0.035 1
Work performance 0.578# 0.007 0.779# 1
Sexual function 0.243* -0.114 0.065 0.064 1
Ureteral stent related infection 0.617# -0.063 0.558# 0.547# 0.099 1

Figure 1

Theoretical model of prolonging the indwelling time of ureteral stent on multidimensional ureteral stent symptoms questionnaire (USSQ)"

Table 5

Path analysis of ureteral stent symptoms questionnaire (USSQ) multidimensional theoretical model by extending the duration time of the stent"

Hypothesis model Estimate CR P Label Chidist
General health Urinary symptom 0.637 6.995 < 0.05 Relationship exist 0.574
Physical pain 0.113 1.241 0.215 No relationship
Work performance Urinary symptom 0.588 6.114 < 0.05 Relationship exist 0.029
Physical pain 0.079 0.821 0.412 No relationship
Urinary symptom Ureteral stent related infection 0.623 6.664 < 0.05 Relationship exist 0.351
Physical pain Ureteral stent related infection -0.057 -0.474 0.636 No relationship
General health Ureteral stent related infection 0.572 5.835 < 0.05 Relationship exist
Work performance Ureteral stent related infection 0.565 5.725 < 0.05 Relationship exist

Table 6

Results of patients' SAS and SDS"

Group SAS SDS
Normal Mild Moderate Severe P Normal Low Moderate Severe P
Control, n(%) 19 (100) 14 (33.3) 2 (20) - < 0.001 19 (86.4) 14 (40) 2 (14.3) - < 0.001
Delayed group, n(%) 0 (0) 28 (66.7) 8 (80) - 3 (13.6) 21 (60) 12 (85.7) - -

Figure 2

Theoretical model of patients' mental status and USSQ multidimensional assessment during the COVID-19 pandemic USSQ, ureteral stent symptoms questionnaire; SAS, self-rating anxiety scale; SDS, self-rating depression scale."

Table 7

Path analysis of patients' mental status and USSQ multidimensional theoretical model during COVID-19 pandemic"

Path diagram Estimate CR P Label
SAS
    Urinary symptom 0.186 1.671 0.095 No relationship
    Physical pain -0.145 -1.226 0.220 No relationship
    General health 0.336 3.389 < 0.05 Relationship exist
    Work performance 0.433 4.500 < 0.05 Relationship exist
    Ureteral stent related infection 0.284 2.694 0.007 Relationship exist
SDS
    Urinary symptom 0.313 2.814 0.005 Relationship exist
    Physical pain 0.056 0.470 0.638 No relationship
    General health 0.446 4.496 < 0.05 Relationship exist
    Work performance 0.405 4.210 < 0.05 Relationship exist
    Ureteral stent related infection 0.376 3.571 < 0.05 Relationship exist
1 Alnadhari I , Alwan MA , Salah MA , et al. Treatment of retained encrusted ureteral double-J stent[J]. Arch Ital Urol Androl, 2019, 90 (4): 265- 269.
doi: 10.4081/aiua.2018.4.265
2 Tae BS , Cho S , Jeon BJ , et al. Does mirabegron relieve ureteric stent-related discomfort? A prospective, randomized, multicentre study[J]. BJU Int, 2018, 122 (5): 866- 872.
doi: 10.1111/bju.14416
3 Bosio A , Alessandria E , Dalmasso E , et al. How bothersome double-J ureteral stents are after semirigid and flexible ureteroscopy: A prospective single-institution observational study[J]. World J Urol, 2019, 37 (1): 201- 207.
doi: 10.1007/s00345-018-2376-6
4 Lin TF , Lin WR , Chen M , et al. The risk factors and complications of forgotten double-J stents: A single-center experience[J]. J Chin Med Assoc, 2019, 82 (10): 767- 771.
doi: 10.1097/JCMA.0000000000000161
5 Rabani SM . Combined percutaneous and transurethral lithotripsy for forgotten ureteral stents with giant encrustation[J]. Nephrourol Mon, 2012, 4 (4): 633- 635.
doi: 10.5812/numonthly.4087
6 Nerli RB , Magdum PV , Sharma V , et al. Forgotten/retained double J ureteric stents: A source of severe morbidity in children[J]. Afr J Paediatr Surg, 2016, 13 (1): 32- 35.
doi: 10.4103/0189-6725.181704
7 Westhofen T , Magistro G , Lennartz S , et al. Confronting hidden COVID-19 burden: A telemedical solution for elective urological outpatient clinics[J]. Infection, 2020, 48 (6): 935- 939.
doi: 10.1007/s15010-020-01511-7
8 Zhu C , Qu J , Yang L , et al. The chinese linguistic validation of the ureteral stent symptom questionnaire[J]. Urol Int, 2019, 102 (2): 194- 198.
doi: 10.1159/000493764
9 Wang C , Zhao H . The Impact of COVID-19 on anxiety in Chinese university students[J]. Front Psychol, 2020, 11, 1168.
doi: 10.3389/fpsyg.2020.01168
10 Lei L , Huang X , Zhang S , et al. Comparison of prevalence and associated factors of anxiety and depression among people affected by versus people unaffected by quarantine during the COVID-19 epidemic in southwestern China[J]. Med Sci Monit, 2020, 26, e924609-1- e924609-12.
11 Wu G , Sun F , Sun K , et al. Impact of differential ureteral stent diameters on clinical outcomes after ureteroscopy intracorporeal lithotripsy: A systematic review and meta-analysis[J]. Int J Urol, 2021, 28 (10): 992- 999.
doi: 10.1111/iju.14631
12 Pecoraro A , Peretti D , Tian Z , et al. Treatment of ureteral stent-related symptoms[J]. Urol Int, 2023, 107 (3): 288- 303.
doi: 10.1159/000518387
13 Bao X , Sun F , Yao H , et al. Distal end of double-J ureteral stent position on ureteral stent-related symptoms: A systematic review and meta-analysis[J]. Front Surg, 2022, 9, 990049.
doi: 10.3389/fsurg.2022.990049
14 Kuehhas FE , Miernik A , Sharma V , et al. A prospective evaluation of pain associated with stone passage, stents, and stent removal using a visual analog scale[J]. Urology, 2013, 82 (3): 521- 525.
doi: 10.1016/j.urology.2013.04.031
15 Polat H , Yucel MO , Utangac MM , et al. Management of forgotten ureteral stents: Relationship between indwelling time and required treatment approaches[J]. Balkan Med J, 2017, 34 (4): 301- 307.
16 Bidnur S , Huynh M , Hoag N , et al. An indwelling ureteral stent forgotten for over 12 years[J]. J Endourol Case Rep, 2016, 2 (1): 135- 137.
doi: 10.1089/cren.2016.0073
17 Nevo A , Mano R , Baniel J , et al. Ureteric stent dwelling time: A risk factor for post-ureteroscopy sepsis[J]. BJU Int, 2017, 120 (1): 117- 122.
doi: 10.1111/bju.13796
18 Ramachandra M , Mosayyebi A , Carugo D , et al. Strategies to improve patient outcomes and QoL: Current complications of the design and placements of ureteric stents[J]. Res Rep Urol, 2020, 12, 303- 314.
19 Kartal IG , Baylan B , Gok A , et al. The association of encrustation and ureteral stent indwelling time in urolithiasis and KUB grading system[J]. Urol J, 2018, 15 (6): 323- 328.
20 Frank A , Hormann S , Krombach J , et al. COVID-19 concerns and worries in patients with mental illness[J]. Psychiatr Prax, 2020, 47 (5): 267- 272.
doi: 10.1055/a-1179-4230
21 Wang Y , Yang Y , Yan C , et al. COVID-induced 3 weeks' treatment delay may exacerbate breast cancer patient's psychological symptoms[J]. Front Psychol, 2022, 13, 1003016.
doi: 10.3389/fpsyg.2022.1003016
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