北京大学学报(医学版) ›› 2017, Vol. 49 ›› Issue (1): 1-005. doi: 10.3969/j.issn.1671-167X.2017.01.001

• 工作综述 •    下一篇

数字化外科技术在上颌骨缺损重建中的应用

章文博,于尧,王洋,刘筱菁,毛驰,郭传瑸,俞光岩,彭歆△   

  1. (北京大学口腔医学院·口腔医院,口腔颌面外科口腔数字化医疗技术和材料国家工程实验室口腔数字医学北京市重点实验室, 北京100081)
  • 出版日期:2017-02-18 发布日期:2017-02-18
  • 通讯作者: 彭歆 E-mail:pxpengxin@263.net
  • 基金资助:

    科技部支撑计划项目课题(2014BAI 04B06)和北京市科委首都市民健康培育项目课题(Z161100000116053)资助

Surgical reconstruction of maxillary defects using a computer-assisted techniques

ZHANG Wen-bo, YU Yao, WANG Yang, LIU Xiao-jing, MAO Chi, GUO Chuan-bin, YU Guang-yan, PENG Xin△   

  1. (Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China)
  • Online:2017-02-18 Published:2017-02-18
  • Contact: PENG Xin E-mail:pxpengxin@263.net
  • Supported by:

    Supported by National Supporting Program for Science and Technology(2014BAI 04B06) and Beijing Municipal Science and Technology Commission (Z161100000116053)

摘要:

上颌骨是面中份结构的基石,毗邻口腔、鼻腔、上颌窦及眼眶,参与上颌眶颧骨复合体等重要的面中份结构的组成。由于肿瘤、外伤或先天性畸形造成的上颌骨缺损,不仅严重影响患者外形,而且直接导致患者的语音、咀嚼、吞咽等生理功能障碍,严重影响患者的生活质量。由于上颌骨及面中份解剖结构的复杂性,使得上颌骨缺损的修复与重建一直是临床医生面临的难题[1]。
1999年以来,本课题组在国内率先开展应用游离组织瓣功能性重建上颌骨缺损的系统研究,提出游离腓骨瓣功能性重建上颌骨缺损的临床应用方法、适应证及围手术期处理原则。同时,通过三维有限元分析探讨腓骨瓣重建上颌骨缺损的生物力学基础,对患者术后的语音功能、咀嚼功能、生存质量及供区并发症等进行了系统的分析评价,客观反映了该方法良好的临床治疗效果,提高了上颌骨缺损修复重建的临床治疗水平[2-7]。

关键词: 上颌骨缺损, 修复外科手术, 外科手术, 计算机辅助, 口腔外科手术, 外科皮瓣

Abstract:

The maxilla is the most important bony support of the mid-face skeleton and is critical for both esthetics and function. Maxillary defects, resulting from tumor resection, can cause severe func-tional and cosmetic deformities. Furthermore, maxillary reconstruction presents a great challenge for oral and maxillofacial surgeons. Nowadays, vascularized composite bone flap transfer has been widely used for functional maxillary reconstruction. In the last decade, we have performed a comprehensive research on functional maxillary reconstruction with free fibula flap and reported excellent functional and acceptable esthetic results. However, this experience based clinical procedure still remainssome problems in accuracy and efficiency. In recent years, computer assisted techniques are now widely used in oral and maxillofacial surgery. We have performed a series of study on maxillary reconstruction with computer assisted techniques. The computer assisted techniques used for maxillary reconstruction mainly include: (1) Three dimensional (3D) reconstruction and tumor mapping: providing a 3D view of maxillary tumor and adjacent structures and helping to make the diagnosis of maxillary tumor accurate and objective; (2) Virtual planning: simulating tumor resection and maxillectomy as well as fibula reconstruction on the compu-ter, so that to make an ideal surgical plan; (3) 3D printing: producing a 3D stereo model for prebending individualized titanium mesh and also providing template or cutting guide for the surgery; (4) Surgical navigation: the bridge between virtual plan and real surgery, confirming the virtual plan during the surgery and guarantee the accuracy; (5) Computer assisted analyzing and evaluating: making a quantitative and objective of the final result and evaluating the outcome. We also performed a series of studies to evaluate the application of computer assisted techniques used for maxillary reconstruction, including: (1) 3D tumor mapping technique for accurate diagnosis and treatment of maxillary tumor; (2) Maxillary reconstruction with free fibula flap used computer assisted techniques; (3) Computer assisted orbital floor reconstruction after maxillectomy. The results suggested that computer assisted techniques could significantly improve the clinical outcome of maxillary reconstruction.

中图分类号: 

  • R782.2
[1] 李怡,王丽瑜,刘晓强,周倜,吕季喆,谭建国. 不同材料及厚度椅旁CAD/CAM瓷贴面的边缘特征[J]. 北京大学学报(医学版), 2022, 54(1): 140-145.
[2] 邱淑婷,朱玉佳,王时敏,王飞龙,叶红强,赵一姣,刘云松,王勇,周永胜. 姿势微笑位口唇对称参考平面的数字化构建及初步应用验证[J]. 北京大学学报(医学版), 2022, 54(1): 193-199.
[3] 苏俊琪,宋扬,谢尚. 口腔鳞状细胞癌患者修复重建术后感染的病原学特征及感染风险预测模型的构建[J]. 北京大学学报(医学版), 2022, 54(1): 68-76.
[4] 朱敬先,鲁胜楠,蒋艳芳,姜玲,王健全. 老年肩袖损伤手术患者术前肺功能的影响因素[J]. 北京大学学报(医学版), 2021, 53(5): 902-906.
[5] 林国中, 马长城, 王振宇, 谢京城, 刘彬, 陈晓东. 1~2硬膜外神经鞘瘤的显微微创治疗[J]. 北京大学学报(医学版), 2021, 53(3): 586-589.
[6] 李新飞, 彭意吉, 余霄腾, 熊盛炜, 程嗣达, 丁光璞, 杨昆霖, 唐琦, 米悦, 吴静云, 张鹏, 谢家馨, 郝瀚, 王鹤, 邱建星, 杨建, 李学松, 周利群. 肾部分切除术前CT三维可视化评估标准的初步探究[J]. 北京大学学报(医学版), 2021, 53(3): 613-622.
[7] 杨阳,肖锋,王进,宋波,李西慧,张师杰,何志嵩,张寰,尹玲. 同期手术治疗心脏病和非心脏疾病[J]. 北京大学学报(医学版), 2021, 53(2): 327-331.
[8] 黄新瑞,李莎,高嵩. 冷冻电镜成像中噪声的滤波方法进展[J]. 北京大学学报(医学版), 2021, 53(2): 425-433.
[9] 孟昭婷,穆东亮. 肺叶切除术中少尿与术后急性肾损伤的关系[J]. 北京大学学报(医学版), 2021, 53(1): 188-194.
[10] 岳兆国,张海东,杨静文,侯建霞. 数字化评估CAD/CAM个性化基台与成品基台影响粘接剂残留的体外研究[J]. 北京大学学报(医学版), 2021, 53(1): 69-75.
[11] 徐啸翔,曹烨,赵一姣,贾璐,谢秋菲. 数字化个齿托盘制取下颌全牙列全冠预备体印模的体外评价[J]. 北京大学学报(医学版), 2021, 53(1): 54-61.
[12] 李峥,柳玉树,王时敏,张瑞,贾璐,叶红强,胡文杰,赵文艳,刘云松,周永胜. 数字化方法复制暂时修复体牙合面形态在重度磨耗病例中的应用[J]. 北京大学学报(医学版), 2021, 53(1): 62-68.
[13] 房硕博,杨广聚,康艳凤,孙玉春,谢秋菲. 数字化辅助确定再定位牙合垫颌位方法的探索和精度评价[J]. 北京大学学报(医学版), 2021, 53(1): 76-82.
[14] 刘世博,高辉,冯元春,李静,张彤,万利,刘燕鹰,李胜光,罗成华,张学武. 腹膜后纤维化致肾盂积水的临床分析:附17例报道[J]. 北京大学学报(医学版), 2020, 52(6): 1069-1074.
[15] 郝柯屹,罗佳,邸萍,郭厚佐,沈惠丹,刘焱萍,张宇,林野. 三维图像融合技术评价上颌全牙列种植固定修复前后的鼻唇软组织形态变化[J]. 北京大学学报(医学版), 2020, 52(5): 924-930.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] 张三. 中文标题测试[J]. 北京大学学报(医学版), 2010, 42(1): 1 -10 .
[2] 赵磊, 王天龙 . 右心室舒张末期容量监测用于肝移植术中容量管理的临床研究[J]. 北京大学学报(医学版), 2009, 41(2): 188 -191 .
[3] 万有, , 韩济生, John E. Pintar. 孤啡肽基因敲除小鼠电针镇痛作用增强[J]. 北京大学学报(医学版), 2009, 41(3): 376 -379 .
[4] 张燕, 韩志慧, 钟延丰, 王盛兰, 李玲玲, 郑丹枫. 骨骼肌活组织检查病理诊断技术的改进及应用[J]. 北京大学学报(医学版), 2009, 41(4): 459 -462 .
[5] 林红, 王玉凤, 吴野平. 学校生活技能教育对小学三年级学生行为问题影响的对照研究[J]. 北京大学学报(医学版), 2007, 39(3): 319 -322 .
[6] 丰雷, 程嘉, 王玉凤. 注意缺陷多动障碍儿童的运动协调功能[J]. 北京大学学报(医学版), 2007, 39(3): 333 -336 .
[7] 李岳玲, 钱秋瑾, 王玉凤. 儿童注意缺陷多动障碍成人期预后及其预测因素[J]. 北京大学学报(医学版), 2007, 39(3): 337 -340 .
[8] . 书讯[J]. 北京大学学报(医学版), 2007, 39(3): 225 -328 .
[9] 牟向东, 王广发, 刁小莉, 阙呈立. 肺黏膜相关淋巴组织型边缘区B细胞淋巴瘤一例[J]. 北京大学学报(医学版), 2007, 39(4): 346 -350 .
[10] 燕太强, 杨荣利, 郭卫, 沈丹华. 胫骨平滑肌肉瘤伴全身多发骨转移一例[J]. 北京大学学报(医学版), 2007, 39(4): 369 -373 .