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Journal of Peking University(Health Sciences) ›› 2015, Vol. 47 ›› Issue (5): 870-874. doi: 10.3969/j.issn.1671-167X.2015.05.027

• Article • Previous Articles     Next Articles

Renal damage caused by Rhupus syndrome associated with anti-neutrophil cytoplasmic antibodies vasculitis and cryoglobulinemia

ZHAO Xin-ju1, WEI Tao1,DONG Bao1, JIA Yuan2, WANG Mei1△   

  1. (1. Department of Nephrology, 2. Department of Rheumatology and Immunology, Peking University People’s Hospital, Beijing 100044, China)
  • Online:2015-10-18 Published:2015-10-18
  • Contact: WANG Mei E-mail:wangmei1949@163.com
  • Supported by:

    Supported by Peking University People’s Hospital Research and Development Funds(2118000533)

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Abstract:

We analyzed the clinicopathological characteristics of one patient with Rhupus syndrome associated nephropathy in Peking University People’s Hospital, and reviewed the related literature. The patient was a middle aged female. She developed rheumatoid arthritis first, and then manifested mild systemic lupus erythematosus together with positive anti-neutrophil cytoplasmic antibodies (ANCA) and cryoglobulinemia several years later. The renal biopsy was performed and manifested as lupus nephritis. The transmission electron microscopy revealed cryoglobulinemia associated renal damage. This report shows that the clinicopathological characteristics in patients with Rhupus syndrome associated nephropathy are complicated. The renal pathology can be used as a diagnostic tool.

Key words: Arthritis, rheumatoid, Lupus erythematosus, systemic, Cryoglobulinemia, Kidney diseases, Biopsy

CLC Number: 

  • R593.22
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