Abstract: Objective：
To investigate the length of interval time between biopsy and laparascopic radical prostatectomy in difficulty and effects of surgery. Methods: We retrospectively analyzed 89 cases of laparascopic radical prostatectomy from June 2011 to September 2013. The patients were divided into two groups according to the interval time of 6 weeks. The mean interval time was 3.1 weeks (ranging from 1.5 to 4.4 weeks) in group IT<6 weeks and 4.4 weeks (ranging from 6.0 to 16.2 weeks) in group IT≥6 weeks. The mean age was 67 years (ranging from 57 to 78 years). The PSA level was 15.4 μg/L (ranging from 5.2 to 72.0). The prostate volume was 55 mL (ranging from 42 to 89 mL). The parameters, such as operation duration, blood loss, positive surgical margin rate, incharge time postoperation, were evaluated. Results: All the surgeries went successfully. The average operation duration was 150 min (ranging from 110 to 242 min), and the blood loss was 230 mL (ranging from 100 to 750 mL). The positive surgical margin rate was 18% and the urinary continence rate was 100% at 3 months after operation. The clinical recurrence was not found during the followup. No significant difference was found between the groups in the patients’ age, preoperative PSA, Gleason score and prostate volume (P>0.05). No statistical significance existed in the operation time, blood loss, positive margin rate, postoperative hospital stay, urinary continence rate at 3 months after operation, postoperative differences of clinical recurrence rates. Conclusion: The length of interval time between prostate biopsy and laparascopic radical prostatectomy does not influence the difficulty and effect in the early stage, and the long time survival and recurrent rate need further observation.

Key words: Prostatic neoplasms, Biopsy, needle, Prostatectomy, Laparoscopy, Time-to-treatment