," /> ,"/> 隐形矫治重度牙周炎患者前牙区病理性移位患牙的临床疗效

北京大学学报(医学版) ›› 2025, Vol. 57 ›› Issue (1): 51-56. doi: 10.19723/j.issn.1671-167X.2025.01.008

• 论著 • 上一篇    下一篇

隐形矫治重度牙周炎患者前牙区病理性移位患牙的临床疗效

李敬谦1, 朱子璐1, 焦剑2, 施捷1,*()   

  1. 1. 北京大学口腔医学院·口腔医院正畸科,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔生物材料和数字诊疗装备国家工程研究中心,北京 100081
    2. 北京大学口腔医学院·口腔医院门诊部,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔生物材料和数字诊疗装备国家工程研究中心,北京 100081
  • 收稿日期:2024-10-09 出版日期:2025-02-18 发布日期:2025-01-25
  • 通讯作者: 施捷 E-mail:sjlily@yeah.net
  • 基金资助:
    北京市自然科学基金-海淀原始创新基金联合基金(L232107)

Clinical efficacy of clear aligner treatment for pathologically migrated teeth in the anterior region of patients with severe periodontitis

Jingqian LI1, Zilu ZHU1, Jian JIAO2, Jie SHI1,*()   

  1. 1. Department of Orthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China
    2. First Clinical Division, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China
  • Received:2024-10-09 Online:2025-02-18 Published:2025-01-25
  • Contact: Jie SHI E-mail:sjlily@yeah.net
  • Supported by:
    the Beijing Natural Science Foundation-Combined Fund of Haidian Original Innovation Fund(L232107)

RICH HTML

  

摘要:

目的: 评估隐形矫治在重度牙周炎伴前牙区病理性移位患者中的临床疗效。方法: 回顾性分析2019—2022年在北京大学口腔医院牙周科和正畸科同时就诊的重度牙周炎伴前牙区病理性移位的患者共26例,患者定期进行牙周基础治疗并维护,均采用隐形矫治器进行正畸治疗,利用软件测量口腔扫描数据,比较正畸前后病理性移位患牙的咬合分布和邻面接触评分,同时评价牙周治疗前和正畸治疗前后牙周临床指标的变化。结果: 26例患者病理性移位的前牙共217颗,其中105颗在牙周治疗前存在探诊深度(probing depth, PD)≥ 5 mm的牙周袋。隐形矫治后,咬合评分由10.35±8.61提高至23.62± 9.73(P < 0.001),邻面接触评分由13.62±4.73提升至31.62± 10.37(P < 0.001)。牙周治疗前(T0),患牙的平均PD中位数为3.33 mm [四分位距(interquartile range, IQR)=0.92];正畸治疗前(T1),PD降至2.50 mm (IQR=0.67,P < 0.001);隐形矫治后(T2),PD仍维持在2.50 mm (IQR=0.50),与T0相比差异有统计学意义(P < 0.001),T1与T2之间差异无统计学意义(P=0.948)。结论: 隐形矫治对重度牙周炎伴前牙区病理性移位的患者具有良好的临床疗效,未来需要更多大样本量的前瞻性对照研究进一步验证其长期临床效果。

关键词: 正畸治疗, 牙周炎, 可摘式正畸矫正器, ')">牙

Abstract:

Objective: To evaluate the clinical efficacy of clear aligner therapy in patients with severe periodontitis accompanied by pathological tooth displacement in the anterior region. Methods: This retrospective study analyzed patients diagnosed with severe periodontitis and pathological displacement in the anterior region, who visited both the Periodontics and Orthodontics Departments at Peking University School and Hospital of Stomatology between 2019 and 2022. A total of 26 eligible cases were included in this study. All the patients underwent regular periodontal maintenance throughout the treatment process, and clear aligners were used for orthodontic treatment. Intraoral scans were analyzed by dedicated software to measure and compare occlusal distribution and proximal contact scores before and after orthodontic treatment. Periodontal clinical indicators were assessed at three key time points: before periodontal treatment (T0), before orthodontic treatment (T1), and after orthodontic treatment (T2). All the cases were treated with clear aligner. Results: A total of 217 pathologically displaced anterior teeth from 26 patients were analyzed. Among these, 105 teeth exhibited periodontal pockets [probing depth (PD) ≥5 mm] before periodontal treatment. After clear aligner therapy, the occlusal score improved significantly from 10.35±8.61 to 23.62±9.73 (P < 0.001), and the proximal contact score increased from 13.62±4.73 to 31.62±10.37 (P < 0.001). The median PD decreased significantly from 3.33 mm [interquartile range (IQR)=0.92] at T0 to 2.50 mm (IQR=0.67, P < 0.001) at T1 and remained stable at 2.50 mm (IQR=0.50) after treatment (T2). A significant reduction in PD was observed between T0 and T2 (P < 0.001), but no significant difference was found between T1 and T2 (P=0.948). Conclusion: Clear aligner therapy demonstrates favorable clinical efficacy in patients with severe periodontitis and pathological anterior tooth displacement. It effectively improves occlusal distribution and proximal contact while maintaining periodontal health in these patients. However, further large-scale prospective controlled studies are needed to verify its long-term clinical outcomes.

Key words: Orthodontic treatment, Periodontitis, Removable orthodontic appliances, Dental occlusion

中图分类号: 

  • R783.5

图1

咬合分布评分积分规则"

图2

隐形矫治前后上下颌咬合力分布变化"

图3

隐形矫治前(T1)和矫治后(T2)患者平均咬合力分布评分(A)和邻面接触评分(B)的变化(均数±标准差,配对t检验)"

图4

牙周治疗前(T0)、隐形矫治前(T1)和矫治后(T2)患牙平均PD (A)、最大PD (B)和最大BI (C)的变化情况(Friedman检验及Dunn多重比较检验)"

图5

牙周治疗前(T0)存在PD ≥5 mm位点的患牙在隐形矫治前(T1)和矫治后(T2)平均PD (A)、最大PD (B)和最大BI (C)的变化情况(Friedman检验及Dunn多重比较检验)"

1 Cobb CM . Clinical significance of non-surgical periodontal therapy: An evidence-based perspective of scaling and root planing[J]. J Clin Periodontol, 2002, 29 (Suppl 2): 6- 16.
2 Tonetti MS , Jepsen S , Jin L , et al. Impact of the global burden of periodontal diseases on health, nutrition and wellbeing of mankind: A call for global action[J]. J Clin Periodontol, 2017, 44 (5): 456- 462.
doi: 10.1111/jcpe.12732
3 Brunsvold MA . Pathologic tooth migration[J]. J Periodontol, 2005, 76 (6): 859- 866.
doi: 10.1902/jop.2005.76.6.859
4 Lee JW , Lee SJ , Lee CK , et al. Orthodontic treatment for maxillary anterior pathologic tooth migration by periodontitis using clear aligner[J]. J Periodontal Implant Sci, 2011, 41 (1): 44- 50.
doi: 10.5051/jpis.2011.41.1.44
5 Khorshidi H , Moaddeli MR , Golkari A , et al. The prevalence of pathologic tooth migration with respect to the severity of periodontitis[J]. J Int Soc Prev Community Dent, 2016, 6 (Suppl 2): S122- S125.
6 Huang YZ , Zhu YR , Yan Y . A retrospective study of orthodontic treatment on anterior tooth displacement caused by periodontal disease[J]. Medicine (Baltimore), 2021, 100 (13): e25181.
doi: 10.1097/MD.0000000000025181
7 Jiang Q , Li J , Mei L , et al. Periodontal health during orthodontic treatment with clear aligners and fixed appliances: A meta-analysis[J]. J Am Dent Assoc, 2018, 149 (8): 712- 720. e12.
doi: 10.1016/j.adaj.2018.04.010
8 Yassir YA , Nabbat SA , McIntyre GT , et al. Clinical effectiveness of clear aligner treatment compared to fixed appliance treatment: An overview of systematic reviews[J]. Clin Oral Investig, 2022, 26 (3): 2353- 2370.
doi: 10.1007/s00784-021-04361-1
9 Guo R , Zheng Y , Liu H , et al. Profiling of subgingival plaque biofilm microbiota in female adult patients with clear aligners: A three-month prospective study[J]. PeerJ, 2018, 6, e4207.
doi: 10.7717/peerj.4207
10 Crego-Ruiz M , Jorba-García A . Assessment of the periodontal health status and gingival recession during orthodontic treatment with clear aligners and fixed appliances: A systematic review and meta-analysis[J]. Med Oral Patol Oral Cirugia Bucal, 2023, 28 (4): e330- e340.
11 曹采方, 孟焕新, 阎福华, 等. 牙周疾病新分类简介(1999年国际研讨会)[J]. 中华口腔医学杂志, 2001, 36 (5): 74- 76.
12 杜仁杰, 焦剑, 周彦恒, 等. 侵袭性牙周炎患者正畸前后的咬合变化[J]. 北京大学学报(医学版), 2019, 51 (5): 919- 924.
doi: 10.19723/j.issn.1671-167X.2019.05.021
13 ElNaghy R , Al-Qawasmi R , Hasanin M . Does orthodontic treatment using clear aligners and fixed appliances affect periodontal status differently?[J]. Evid Based Dent, 2023, 24 (2): 73- 74.
doi: 10.1038/s41432-023-00890-8
14 Rouzi M , Zhang X , Jiang Q , et al. Impact of clear aligners on oral health and oral microbiome during orthodontic treatment[J]. Int Dent J, 2023, 73 (5): 603- 611.
doi: 10.1016/j.identj.2023.03.012
15 Thirumoorthy SN , Gopal S . Is remote monitoring a reliable method to assess compliance in clear aligner orthodontic treatment?[J]. Evid Based Dent, 2021, 22 (4): 156- 157.
doi: 10.1038/s41432-021-0231-x
16 Perillo L , d'Apuzzo F , De Gregorio F , et al. Factors affecting patient compliance during orthodontic treatment with aligners: Motivational protocol and psychological well-being[J]. Turk J Orthod, 2023, 36 (2): 87- 93.
doi: 10.4274/TurkJOrthod.2022.2021.0255
[1] 石宇彤, 危伊萍, 胡文杰, 徐涛, 张浩筠. 罹患重度牙周炎下颌磨牙拔牙微翻瓣牙槽嵴保存效果评价[J]. 北京大学学报(医学版), 2025, 57(1): 33-41.
[2] 胡玉如,刘娟,李文静,赵亦兵,李启强,路瑞芳,孟焕新. Ⅲ期或Ⅳ期牙周炎患者龈沟液中有机酸浓度与牙周炎的关系[J]. 北京大学学报(医学版), 2024, 56(2): 332-337.
[3] 张晗,秦亦瑄,韦帝远,韩劼. 牙周炎患者种植修复维护治疗依从性的影响因素[J]. 北京大学学报(医学版), 2024, 56(1): 39-44.
[4] 殳畅,韩烨,孙雨哲,杨再目,侯建霞. Ⅲ期牙周炎患者牙周基础治疗前后炎症性贫血相关指标的变化[J]. 北京大学学报(医学版), 2024, 56(1): 45-50.
[5] 裴喜燕,阳雯,欧阳翔英,孙凤. 牙周内窥镜下根面清创与牙周翻瓣术疗效比较[J]. 北京大学学报(医学版), 2023, 55(4): 716-720.
[6] 温静,欧阳翔英,裴喜燕,邱善湧,刘健如,刘文逸,曹采方. 重度牙周炎患者4年自然进展失牙的多因素分析[J]. 北京大学学报(医学版), 2023, 55(1): 70-77.
[7] 朱小玲,李文静,王宪娥,宋文莉,徐莉,张立,冯向辉,路瑞芳,释栋,孟焕新. 细胞色素B-245α链及胆固醇酯转运蛋白基因多态性与广泛型侵袭性牙周炎易感性的关系[J]. 北京大学学报(医学版), 2022, 54(1): 18-22.
[8] 徐欣然,霍芃呈,和璐,孟焕新,朱筠轩,靳东思奇. 伴与不伴糖尿病的牙周炎患者牙周基础治疗的疗效比较及其与白细胞水平的相关分析[J]. 北京大学学报(医学版), 2022, 54(1): 48-53.
[9] 郜洪宇,孟焕新,侯建霞,黄宝鑫,李玮. 钙结合蛋白在健康牙周组织和实验性牙周炎组织的表达分布[J]. 北京大学学报(医学版), 2021, 53(4): 744-749.
[10] 刘建,王宪娥,吕达,乔敏,张立,孟焕新,徐莉,毛铭馨. 广泛型侵袭性牙周炎患者牙根形态异常与相关致病基因的关联[J]. 北京大学学报(医学版), 2021, 53(1): 16-23.
[11] 郜洪宇,徐菁玲,孟焕新,和璐,侯建霞. 牙周基础治疗对2型糖尿病伴慢性牙周炎患者红细胞、血小板相关指标的影响[J]. 北京大学学报(医学版), 2020, 52(4): 750-754.
[12] 闫乐,王宪娥,詹雅琳,苗莉莉,韩烨,张楚人,岳兆国,胡文杰,侯建霞. 超声龈下清创联合手工根面平整术治疗重度牙周炎的临床效果[J]. 北京大学学报(医学版), 2020, 52(1): 64-70.
[13] 张勇,刘畅,陈彬,陈帆,段晋瑜,张孟钧,焦剑. 糖尿病前期患者糖代谢异常与慢性牙周炎的相关性[J]. 北京大学学报(医学版), 2020, 52(1): 71-76.
[14] 朱洁,李建红,袁婷婷,和璐,梁宇红. 绝经期妇女牙周状况与骨质密度的相关性分析[J]. 北京大学学报(医学版), 2019, 51(6): 1115-1118.
[15] 石姝雯,孟洋,焦剑,李文静,孟焕新,栾庆先,王万春. 根分叉病变患牙经牙周非手术治疗后5年失牙状况及多因素分析[J]. 北京大学学报(医学版), 2019, 51(5): 913-918.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!