目的：探讨国产新型可拆卸式输尿管软镜治疗上尿路结石过程中的有效性和安全性。方法：2013年11月至2014年7月，北京大学人民医院泌尿外科应用国产新型可拆卸式输尿管软镜配合钬激光治疗上尿路结石36例，对患者结石位置、大小、手术时间、清石率、术后并发症及术后出院时间等临床资料进行回顾性分析。结果：成功处理结石34例，失败2例，手术时间为70~145 min（平均108.5 min），术后住院时间为2~5 d（平均2.3 d），清石率为83.33%，术后发热2例，出血1例，无其他并发症。结论：应用国产新型可拆卸式输尿管软镜可以安全、有效地处理大部分上尿路结石。

Objective：To evaluate the feasibility and efficacy of novel modular flexible ureteroscope in the treatment of upper urinary calculi. Methods: From Nov. 2013 to Jul. 2014, 36 cases of upper urinary calculi were treated with holmium laser lithotripsy through novel modular flexible ureteroscope. The clinical data including the location and diameter of the calculi, time of operation, stonefree rate, complications and hospital stay after operation were analyzed retrospectively.Results: The operation was performed successfully in 34 cases, the average time of operation was 108.5 min (70-145 min), the postoperation hospital stay was 2-5 d (average 2.3 d), and the stonefree rate was 83.33%. No serious complications occurred except postoperative fever in 2 cases and haemorrhage in 1 case. Conclusion: The novel modular flexible ureteroscope is a safe and effective medical instrumentation for treatment of upper urinary calculi.