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颈动脉支架成形术血流动力学损害的相关因素分析

  • 韩金涛 ,
  • 赵海燕 ,
  • 李选 ,
  • 和清源 ,
  • 叶珊 ,
  • 董国祥 ,
  • 傅军 ,
  • 栾景源 ,
  • 王昌明 ,
  • 李天润
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  • (北京大学第三医院1.介入血管外科, 2.神经内科, 3.放射科, 北京100191)

网络出版日期: 2015-10-18

Related factors of hemodynamic damage after carotid artery stenting

  • HAN Jin-tao ,
  • ZHAO Hai-yan ,
  • LI Xuan ,
  • HE Qing-yuan ,
  • YE Shan ,
  • DONG Guo-xiang ,
  • FU Jun ,
  • LUAN Jing-yuan ,
  • WANG Chang-ming ,
  • LI Tian-run
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  • (1.Department of Interventional Radiology and Vascular Surgery, 2.Department of Neurology, 3.Department of Radiology, Peking University Third Hospital, Beijing 100191, China)

Online published: 2015-10-18

摘要

目的:分析颈动脉支架成形术后造成血流动力学损害的相关因素。方法:回顾分析66例(71处病变)接受颈动脉支架成形术患者围手术期血流动力学损害的相关因素。结果:71例次颈动脉支架成形术中,血流动力学损害发生率为32.4%(23/71),其中低血压发生率为11.3%。单因素分析显示,病变距离颈动脉分叉的距离(P=0.002 0)、斑块分布(P=0.000 2)、斑块性质(P=0.001 9)和后扩张(P=0.002 6)与血流动力学损害有关,然而多因素分析中只有偏心斑块(P=0.015 3)和钙化斑块(P=0.009 7)与血流动力学损害相关。所有病例在术中通过药物治疗即能达到循环稳定,无围手术期短暂性脑缺血事件及卒中事件,无围手术期心血管缺血事件。结论:病变与分叉部的距离、偏心斑块、钙化斑块是血流动力学损害的相关危险因素。

本文引用格式

韩金涛 , 赵海燕 , 李选 , 和清源 , 叶珊 , 董国祥 , 傅军 , 栾景源 , 王昌明 , 李天润 . 颈动脉支架成形术血流动力学损害的相关因素分析[J]. 北京大学学报(医学版), 2015 , 47(5) : 804 -808 . DOI: 10.3969/j.issn.1671-167X.2015.05.014

Abstract

Objective:To analyze correlation factors of hemodynamic damage after carotid artery stenting. Methods: In this study, 66 cases (71 lesions) who undertook carotid artery stenting were collected and the correlation factors of hemodynamic damage were analyzed. Results: Hemodynamic damage emerged in 23 cases (32.4%), of which, 11.3% developed hypotension. The distance between bifurcation and lesions (P=0.002 0), plaque distribution (P=0.000 2), plaque character (P=0.001 9), postdilation (P=0.002 6) were associated with hemodynamic damage by single factor analysis. However, only eccentric plaque (P=0.015 3) and calcified plaque (P=0.009 7) were associated with hemodynamic damage by multiple factors analysis. All the patients could reach stable circulation by drugs during operation, and no cerebral ischemic events (transient ischemic attack or stroke) and cardiovascular ischemic events happened. Conclusion: The distance between bifurcation and lesions, eccentric plaques, calcified plaques are correlation factors of hemodynamic damage.

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