Chronic periodontitis with Takayasu arteritis: a case report
Online published: 2015-10-18
Supported by
Supported by The National Key Clinical Speciality Vocational School (2010) and Capital Medical Development Funds (2009-1019)
大动脉炎是一种罕见的慢性血管炎,患病率为每年(1.2~2.6)/100万,患者多为年轻女性[1],病损主要累及主动脉及其分支[2],其病因尚不明确,感染、自身免疫及遗传缺陷等都是可能的危险因素。美国风湿病学会对大动脉炎的诊断有明确规范[3],大动脉炎的治疗主要包括药物(如类固醇类)和手术(如血管成形术)等[4]。由于大动脉炎可能不断进展并造成重要器官缺血,因此需长期监测患者的红细胞沉降率(erythrocyte sedimentation rate,ESR)及C反应蛋白(Creactive protein,CRP)水平来了解疾病的活动性。研究表明,牙周炎通过牙周致病菌和炎症因子与多种全身系统疾病(如糖尿病、冠心病和动脉粥样硬化等)存在着相关关系[5],但目前还未见大动脉炎与牙周炎关系的相关报道,本研究将对1例伴大动脉炎的牙周炎患者进行报道。
关键词: 牙周炎; Takayasu动脉炎; 病例报告
高巍 , 栾庆先 . 伴大动脉炎的牙周炎1例[J]. 北京大学学报(医学版), 2015 , 47(5) : 875 -877 . DOI: 10.3969/j.issn.1671-167X.2015.05.028
This case report concerns a 23-year-old woman with chronic periodontitis who had been previously diagnosed with Takayasu arteritis (TA). Her erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) level were decreased before and 3 months after non-surgical periodontal therapy with no change in her prescribed medications (ESR from 31.00 mm/h to 23.0 mm/h, CRP from 21.40 mg/L to 18.46 mm/h). Through the occasional findings, we raised a hypothetical analysis about the potential relationship between periodontitis and TA with respect to inflammatory factors, bacteria and medication. Further studies of large samples are needed to verify the findings.
Key words: Periodontitis; Takayasu arteritis; Case reports
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