病例报告

伴大动脉炎的牙周炎1例

  • 高巍 ,
  • 栾庆先
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  • (北京大学口腔医学院·口腔医院牙周科, 北京100081)

网络出版日期: 2015-10-18

基金资助

国家临床重点专科建设项目(2010)和首都医学发展基金(2009-1019)资助

Chronic periodontitis with Takayasu arteritis: a case report

  • GAO Wei ,
  • LUAN Qing-xian
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  • (Department of Periodontology, Peking University School and Hospital of Stomatology, Beijing 100081, China)

Online published: 2015-10-18

Supported by

Supported by The National Key Clinical Speciality Vocational School (2010) and Capital Medical Development Funds (2009-1019)

摘要

大动脉炎是一种罕见的慢性血管炎,患病率为每年(1.2~2.6)/100万,患者多为年轻女性[1],病损主要累及主动脉及其分支[2],其病因尚不明确,感染、自身免疫及遗传缺陷等都是可能的危险因素。美国风湿病学会对大动脉炎的诊断有明确规范[3],大动脉炎的治疗主要包括药物(如类固醇类)和手术(如血管成形术)等[4]。由于大动脉炎可能不断进展并造成重要器官缺血,因此需长期监测患者的红细胞沉降率(erythrocyte sedimentation rate,ESR)及C反应蛋白(Creactive protein,CRP)水平来了解疾病的活动性。研究表明,牙周炎通过牙周致病菌和炎症因子与多种全身系统疾病(如糖尿病、冠心病和动脉粥样硬化等)存在着相关关系[5],但目前还未见大动脉炎与牙周炎关系的相关报道,本研究将对1例伴大动脉炎的牙周炎患者进行报道。

本文引用格式

高巍 , 栾庆先 . 伴大动脉炎的牙周炎1例[J]. 北京大学学报(医学版), 2015 , 47(5) : 875 -877 . DOI: 10.3969/j.issn.1671-167X.2015.05.028

Abstract

This case report concerns a 23-year-old woman with chronic periodontitis who had been previously diagnosed with Takayasu arteritis (TA). Her erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) level were decreased before and 3 months after non-surgical periodontal therapy with no change in her prescribed medications (ESR from 31.00 mm/h to 23.0 mm/h, CRP from 21.40 mg/L to 18.46 mm/h). Through the occasional findings, we raised a hypothetical analysis about the potential relationship between periodontitis and TA with respect to inflammatory factors, bacteria and medication. Further studies of large samples are needed to verify the findings.

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