目的：评价腭侧入路改良Le Fort Ⅰ型截骨术矫正唇腭裂继发上颌骨发育不足畸形的临床效果。方法： 选取2012年1月至2013年12月于北京大学口腔医院行腭侧入路改良Le Fort Ⅰ型截骨术矫正唇腭裂继发上颌骨发育不足畸形的11例患者（男性7例，女性4例），平均年龄21岁（17~28岁），其中9例患者同期行双侧下颌升支矢状劈开截骨术(bilateral sagittal split ramus osteotomy,BSSRO)和颏成形术以获得良好的容貌。分别于术前、术后即刻、术后6个月时拍摄头颅定位侧位X线片，测量上齿槽座点（A）水平移动量、蝶鞍中心点-鼻根点-上牙槽座点角(angle of sella-nasion-subsipmale, SNA)和蝶鞍中心点-鼻根点-下牙槽座点角(angle of sellanasionsupramental, SNB)的度数以评价畸形矫正效果。结果： 所有患者均顺利完成手术,颌骨畸形矫正效果满意,咬合关系良好。术后即刻上颌骨A点水平前徙量平均为（6.6±1.1）mm，术后6个月时平均为（6.0±1.2）mm。SNA术前平均为75.9°±2.8°,术后即刻时平均为81.6°±8.6°，术后6个月时平均为81.0°±2.6°； SNB术前平均为82.6°±3.7°,术后即刻时平均为78.0°±2.4°，术后6个月时平均为78.5°±2.4°。结论： 腭侧入路改良Le Fort Ⅰ型截骨术可成功矫正唇腭裂术后继发上颌骨发育不足畸形，并获得良好的咬合功能；该术式术中解除了腭侧瘢痕组织的牵拉，能使上颌骨前移更充分，可获得满意的临床疗效。

Objective：To evaluate the surgical corrective results of maxillary hypoplasia in patients with cleft lip and palate withtranspalatal modified Le Fort Ⅰ osteotomy. Methods: In the study, 11 patients (4 women, and 7 men) with maxillary hypoplasia secondary to cleft lip and palate underwent transpalatal modified Le Fort Ⅰ osteotomy at Peking University School of Stomatology from Jan. 2012 to Dec. 2013,with the mean age of 21 years ( from 18 to 27 years), Bilateral sagittal split ramus osteotomy (BSSRO)and genioplasty were performed simultaneously in 9 of them for better appearance and functional occlusion. Lateral cephalometric radiographs were taken and traced before surgery, immediately after surgery and 6 months after surgery. The position of subspinale (A) on horizontal direction, the angle of sella-nasion-subsipmale (SNA) and the angle of sella-nasion-supramental (SNB) were collected and analyzed to evaluate the results. Results: All the patients were uneventful with transpalatal modified Le Fort Ⅰ osteotomy. All of them had a better profile and a satisfactory occlusionafter operation.The position of A was moved forward (6.6±1.1) mm on average in horizontal direction when surgery was completed, and maintained (6.0±1.2) mm on average 6 months after surgery. The average of SNA was 75.9°±2.8° before surgery,81.6°±8.6° immediately after surgery, and maintained 81.0°±2.6° 6 months after surgery. The average of SNB was 82.6°±3.7° before surgery, 78.0°±2.4° immediately after surgery, and maintained 78.5°±2.4° 6 months after surgery. Conclusion: The maxillary hypoplasia in cleft lip and palate patients can be successfully corrected with transpalatal modified Le Fort Ⅰ osteotomy and the functional occlusion can be achieved simultaneously. The effect of deformity correction was satisfactory. Transpalatal modified Le Fort Ⅰ osteotomy can move maxilla more sufficiently, especially applicable for the patient with severe palatal scars preoperatively.