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肿瘤早期预警生物标志物的研究与思考

  • 柯杨 ,
  • 王敏敏 ,
  • 刘萌飞 ,
  • 刘芳芳 ,
  • 刘英 ,
  • 何忠虎
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柯杨,教授,研究员,博士生导师,美国医学科学院外籍院士,北京大学肿瘤医院遗传学研究室主任。北京大学原常务副校长、北京大学医学部原常务副主任、第十一/十二届全国政协委员。现任北京大学校友会常务副会长、北京大学医学部校友会会长、中国女医师协会副会长、中国癌症基金会副理事长、北京癌症防治学会轮值理事长、北京医师协会安宁疗护专委会主任、中国老年学老年医学学会老年教育分会主任等职务。
主要研究方向为上消化道恶性肿瘤的病因及其机制,人群精准防治技术策略及健康相关大数据的转化应用。前期克隆多个新的癌变相关基因并进行了功能探索。近年来致力于食管癌人群及分子流行病学方向,在食管癌高发区建立两个大型人群队列,开展了“食管癌流行病学及病因学”“人乳头状瘤病毒(HPV)感染的分子流行病学”“食管癌精准化早期筛查与诊断的关键技术和适宜策略”等系统科研工作,为我国食管癌高发病因探索、HPV相关肿瘤的人群防控、内镜筛检食管癌效果及其卫生经济学评价等重大科学问题提供高规格流行病学证据。
主持863计划、973计划、国家自然基金、科技部重大项目、卫生部公益性行业科研专项、北京市自然科学基金重大项目、北京市科委重大项目等。累计发表中英文科研论文百余篇,被引用1 000余次。培养各类研究生60余名,申请国内外专利10余项。曾获卫生部首届百名科技之星、北京市科技进步二等奖、卫生部科技进步三等奖、国家科技进步二等奖等奖项|何忠虎,北京大学肿瘤医院研究员,博士生导师,遗传学研究室副主任,基础教研室副主任,北京大学肿瘤医院临床研究管理委员会委员,北京肿瘤医院伦理委员会委员。入选“北京市百千万人才工程”和“北京市卫生系统高层次卫生技术(215)人才计划”。
研究方向为“恶性肿瘤精准防治的人群与临床流行病学研究”和“健康相关大数据的挖掘应用”。聚焦我国上消化道肿瘤精准防诊治领域关键瓶颈问题,带领团队长期扎根我国农村高发区一线,与地方政府及医疗机构合作建立研究基地,开展系统性攻关工作。
承担国家重点研发计划、国家科技基础资源调查重点专项、国家自然科学基金、973计划、北京市自然科学基金、北京市消化协同中心重点项目等纵向课题十余项。累积发表科研论文80余篇,其中第一/责任作者英文论文43篇(总IF: 376.64),主编/参编专著4部,申报发明专利4项,获批软件著作权1项

收稿日期: 2022-06-27

  网络出版日期: 2022-10-14

本文引用格式

柯杨 , 王敏敏 , 刘萌飞 , 刘芳芳 , 刘英 , 何忠虎 . 肿瘤早期预警生物标志物的研究与思考[J]. 北京大学学报(医学版), 2022 , 54(5) : 810 -813 . DOI: 10.19723/j.issn.1671-167X.2022.05.005

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