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Journal of Peking University (Health Sciences) ›› 2022, Vol. 54 ›› Issue (3): 505-510. doi: 10.19723/j.issn.1671-167X.2022.03.016

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Trend analysis of influenza vaccination among hospitalized elderly people in Beijing, 2013-2019

Guang-qi LIU1,Yuan-jie PANG2,Jiang WU3,Min LV3,*(),Meng-ke YU1,Yu-tong LI1,Yang-mu HUANG1,*()   

  1. 1. Department of Global Health, Peking University School of Public Health, Beijing 100191, China
    2. Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China
    3. Beijing Center for Disease Prevention and Control, Beijing Research Center for Preventive Medicine, Beijing 100013, China
  • Received:2021-12-22 Online:2022-06-18 Published:2022-06-14
  • Contact: Min LV,Yang-mu HUANG E-mail:8872lm@163.com;ymhuang@bjmu.edu.cn
  • Supported by:
    Capital Health Development Research Fund for Independent Innovation Project(2022-2G-3017);Pilot Project Fund for Public Welfare Development and Reform of Beijing Municipal Medical Research Institutes(2018-1)

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Abstract:

Objective: To analyze the influenza vaccination trend of hospitalized elderly people (≥ 60 years old) in Beijing from 2013 to 2019. Methods: The influenza vaccination status and hospitalization information of elderly people were extracted from the Beijing Elderly Influenza Vaccination database (2013-2019) and the Beijing Urban Employee Basic Medical Insurance database (2013-2019), se-parately. The influenza vaccine coverage rates and annual percentage change were calculated to compare the vaccination trends of elderly people hospitalized due to different diseases. The subjects in 2018-2019 influenza season were divided into different groups according to demographic status, health conditions and hospitalization outcomes to describe and compare the distribution of influenza vaccination rates. Results: The influenza vaccine coverage rates among the elderly people hospitalized due to cardiovascular diseases, cerebrovascular diseases, respiratory diseases or diabetes mellitus were 14.6%, 13.4%, 13.4% and 11.8%, respectively. The influenza vaccination rate among those hospitalized for cardiovascular diseases remained the highest across six influenza seasons and those hospitalized for diabetes mellitus remained the lowest. The largest annual decline of influenza vaccine coverage rate was observed among the hospitalized elderly due to diabetes mellitus (-7.85%). The distribution of vaccinated population was significantly associated with age, gender, hospitalization outcome and comorbidities among the hospitalized elderly people with specific diseases in 2018-2019. Among the elderly people hospitalized due to four different diseases, the vaccination rate of the patients aged 70-79 years was higher than that of the other age groups and that of the patients aged 60-69 years was the lowest. Among the elderly people hospitalized due to respiratory diseases, the vaccination rate of men was higher than that of women, while the situation reversed among the elderly people hospitalized due to cardiovascular diseases and diabetes mellitus. Vaccination rates decreased among the older adults with poor hospitalization outcomes. Among the elderly people hospitalized due to diabetes mellitus, those with 0 comorbidity had the lowest vaccination rate (7.9%). Conclusion: The trend of influenza vaccine coverage rates among the elderly people in Beijing from 2013 to 2019 was downward. We should pay more attention to influenza vaccination in elderly people with diabetes mellitus and aged 60-69 years, and carry out more research on the protective effects of influenza vaccine to promote influenza vaccine coverage among people with chronic diseases.

Key words: Influenza vaccines, Vaccination coverage, Aged, Chronic diseases

CLC Number: 

  • R186

Table 1

Influenza vaccination status among hospitalized elderly people in Beijing from 2013 to 2019 [n (%)]"

Year Diabetes mellitus Cardiovascular diseases Cerebrovascular diseases Respiratory diseases
2013-2014 1 819 (16.0) 5 844 (19.4) 4 668 (16.6) 5 114 (16.6)
2014-2015 2 071 (13.5) 6 061 (15.7) 5 136 (14.2) 5 805 (14.5)
2015-2016 2 002 (11.9) 6 073 (14.1) 5 038 (12.9) 5 620 (12.8)
2016-2017 1 928 (10.1) 5 886 (12.2) 4 738 (11.0) 5 703 (11.7)
2017-2018 2 770 (11.7) 9 273 (14.8) 8 821 (14.4) 8 766 (13.8)
2018-2019 2 687 (10.4) 9 370 (13.6) 8 729 (12.7) 8 441 (12.5)
Total 13 277 (11.8) 42 507 (14.6) 37 130 (13.4) 39 449 (13.4)
APC -7.63 -5.81 -4.11 -4.57

Table 2

Comparison of vaccination and general characteristics among hospitalized elderly people in Beijing from 2018 to 2019"

Items Diabetes mellitus Cardiovascular diseases Cerebrovascular diseases Respiratory diseases
Vaccination coverage rate/% P Vaccination coverage rate/% P Vaccination coverage rate/% P Vaccination coverage rate/% P
Age < 0.001 0.001 0.883 < 0.001
  60-69 years 7.3 9.6 9.3 10.0
  70-79 years 15.6 19.2 17.0 16.6
  ≥80 years 12.9 14.4 12.9 11.6
Gender < 0.001 < 0.001 < 0.001 < 0.001
  Male 9.4 13.2 12.7 13.3
  Female 11.3 14.1 12.7 11.6

Table 3

Comparison of vaccination and hospitalization conditions among hospitalized elderly people in Beijing from 2018 to 2019"

Items Diabetes mellitus Cardiovascular diseases Cerebrovascular diseases Respiratory diseases
Vaccination coverage rate/% P Vaccination coverage rate/% P Vaccination coverage rate/% P Vaccination coverage rate/% P
CCI 0.143 < 0.001 < 0.001 < 0.001
  0 7.9 14.4 11.3 15.1
  1-2 10.1 14.2 13.7 14.0
  3-4 10.6 13.2 12.1 11.1
  ≥5 10.1 10.2 10.2 8.4
Readmission 0.120 < 0.001 < 0.001 < 0.001
  No 10.5 13.8 13.3 13.2
  Yes 9.5 11.3 8.8 8.2
Death 0.034 < 0.001 < 0.001 < 0.001
  No 10.4 13.7 12.8 13.0
  Yes 3.2 8.7 7.5 4.8
Ht < 0.001 < 0.001 < 0.001 < 0.001
  0 10.9 14.4 13.8 14.1
  1 10.6 13.3 12.8 12.7
  ≥2 7.5 10.5 7.8 8.4
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