Abstract: Objective：To determine whether the extruded irrigation solution bag during passage of rigid cystoscope will reduce the patient’s discomfort.Methods: In the study, 378 male patients undergoing rigid cystoscopies were randomized into “Institute of Urology Peking University (IUPU)” technique group (n=193) and routine manipulation group (n=185). All the patients had received 10 mL oxybuprocaine gel before manipulation. In the IUPU technique group, irrigation solution bag was connected with cystoscope sheath and obturator. As the scope passed through the bulbar urethra, a nurse was instructed to extrude the irrigating fluid bag. A 10-point visual analog pain scale assessment was completed by the patient after the procedure. Results: The visual analog pain score was 2 (1-2) in the IUPU technique group and 4 (3-6) in the routine manipulation group (P<0.001, Mann-Whitney U test). All the procedure indications had no effect on the findings.Conclusion: This study has shown that a simple IUPU technique can significantly reduce the patient’s discomfort during outpatient rigid cystoscopy. We strongly recommend this technique for all male patients undergoing rigid cystoscopy.

Key words: Cystoscopy, Prospective studies, Male