Journal of Peking University(Health Sciences) ›› 2016, Vol. 48 ›› Issue (2): 230-233. doi: 10.3969/j.issn.1671-167X.2016.02.009

• Article • Previous Articles     Next Articles

Effect of radiotherapy and indomethacin together in the prevention of recurrence of ectopic ossification around the elbow after resection

LIU Xing-hua, JIANG Xie-yuan△, GONG Mao-qi, ZHA Ye-jun   

  1. (Department of Orthopedic and Traumotology, Beijing Jishuitan Hospital, Beijng 100035, China)
  • Online:2016-04-18 Published:2016-04-18
  • Contact: JIANG Xie-yuan E-mail:jxy0845@sina.com

Abstract:

Objective:To discuss the effect of single low dose local radiotherapy and indomethacin together in the prevention of recurrence of ectopic ossification around the elbow after resection. Methods: From Jun. 2009 to Dec. 2011, we performed excision of ectopic ossification around the elbow in 78 stiff elbows. For each case, we used both medial and lateral approaches, and we performed both anterior and posterior capsulectomies and removal of ectopic ossification. In the lateral approach, we started proximally, the lateral supracondylar ridge of the humerus was exposed from the interval between extensor carpi radialis longus (ECRL) and triceps, and then distally passed the interval between ECRL and extensor carpi radialis brevis (ECRB). With the medial approach, after releasing the ulnar nerve, the pronator teres muscle origin was reflected from the medial epicondyle, and then the common flexor-pronator tendon was split longitudinally distally and the brachalis and the anterior portion of the flexor-pronator group were dissected off the anterior humerus. If there was forearm rotation dysfunction, we used extensive lateral approach, the anconeus muscle was reflected from the ulna and the scar tissue and ectopic ossification around the proximal radioulnar joint were resected. The important structures, such as the lateral ulnar collateral ligament (LUCL) and the anterior part of the medial collateral ligament (AMCL), should be carefully protected, because they were important for the elbow stability. Anterior transposition of the ulnar nerve depended on the patients’ condition. We performed low dose radiotherapy 4 hours before operation, and we used indomethacin for 6 weeks after operation. In these patients, there were 46 males and 32 females, whose age averaged (35.8±7.9) years (16-65 years). According to Hastings-Graham classification, there were 56 ⅡA, 5 ⅡB, 6 ⅡC and 11 Ⅲ before operation.  Results: We followed up these patients for 26 months with an average of 24-36 months, all the patients improved their elbow function, and no recurrence of ectopic ossification appeared except for 1 patient. For this patient, his elbow function was excellent, and according to Hastings-Graham classification, his ectopic ossification was of type Ⅰ. Conclusion: Single low dose local radiotherapy and indomethacin together are effective in the prevention of recurrence of ectopic ossification around the elbow after excision.

Key words: Elbow joint, Ossification, heterotopic, Radiotherapy, Indomethacin

CLC Number: 

  • R684
[1] Shengjia PENG,Yu QI,Lijie SUN,Dan LI,Xinyu WANG,Jiangli HAN,Baoxia CHEN,Yuan ZHANG. Afferent baroreflex failure with hyponatremia: A case report [J]. Journal of Peking University (Health Sciences), 2024, 56(2): 357-361.
[2] Hai-hong JIANG,Xiao-fan LI,Jian-liu WANG. Relationship between chronic radiation enteritis of cervical cancer and gut microbiota [J]. Journal of Peking University (Health Sciences), 2023, 55(4): 619-624.
[3] Hao WANG,Shu-kun JIANG,Ran PENG,Yi HUANG,Ming-qing WANG,Jun-jie WANG,Cheng LIU,Fan ZHANG,Lu-lin MA. Individual control of urine volume to improve stability of bladder volume in radiotherapy of urinary tumor [J]. Journal of Peking University (Health Sciences), 2020, 52(4): 688-691.
[4] SUN Hai-tao, YANG Rui-jie, JIANG Ping, JIANG Wei-juan, LI Jin-na, MENG Na, WANG Jun-jie. Dosimetric analysis of volumetric modulated arc therapy and intensity modulated radiotherapy for patients undergone breast-conserving operation [J]. Journal of Peking University(Health Sciences), 2018, 50(1): 188-192.
[5] GUO Fu-xin, JIANG Yu-liang, JI Zhe, PENG Ran, SUN Hai-tao, WANG Jun-jie. 3D printed template-assisted and computed tomography image-guided 125-iodine seed implantation for supraclavicular metastatic tumor: a dosimetric study [J]. Journal of Peking University(Health Sciences), 2017, 49(3): 506-511.
[6] ZHA Ye-jun, JIANG Xie-yuan, GONG Mao-qi. Treatment of the old terrible triad of the elbow without operative history [J]. Journal of Peking University(Health Sciences), 2016, 48(2): 224-229.
[7] JIANG Ping, ZHOU Shun,WANG Jun-jie, YANG Rui-jie, LIU Zi-yi, JIANG Shu-kun, WANG Wei. Errors in six degree-of-freedom pose estimation of spine tumors assessed by image guided radiotherapy [J]. Journal of Peking University(Health Sciences), 2015, 47(6): 952-956.
[8] WANG Qing-guo, LI Xiao-mei, ZHANG Min, LI Hang, WEN Bing, LI Hong-zhen, GAO Xian-shu. Effect of two dose fractionations on postoperative radiotherapy of keloid: an analysis of 107 patients [J]. Journal of Peking University(Health Sciences), 2014, 46(1): 169-172.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!