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回肠代输尿管术治疗医源性长段输尿管损伤

  • 刘沛 ,
  • 吴鑫 ,
  • 朱雨泽 ,
  • 唐琦 ,
  • 方冬 ,
  • 李学松△ ,
  • 郝金瑞 ,
  • 周利群
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  • (北京大学第一医院泌尿外科,北京大学泌尿外科研究所,国家泌尿、男性生殖系肿瘤研究中心,北京100034)

网络出版日期: 2015-08-18

Ileal ureteric replacement for iatrogenic long segment ureteric injuries

  • LIU Pei ,
  • WU Xin ,
  • ZHU Yu-Ze ,
  • TANG Qi ,
  • FANG Dong ,
  • LI Xue-Song-△ ,
  • HAO Jin-Rui ,
  • ZHOU Li-Qun
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  • (Department of Urology, Peking University First Hospital; Institute of Urology, Peking University; National Urological Cancer Center, Beijing 100034, China )

Online published: 2015-08-18

摘要

目的:探讨应用回肠代输尿管术治疗医源性长段输尿管损伤的疗效。方法:总结自2010年8月至2014年9月期间接受回肠代输尿管术的9例医源性长段输尿管损伤患者的临床资料,其中男性3例,女性6例,中位年龄40岁。中位输尿管损伤长度为20 cm,范围13~25 cm。常见医源性输尿管损伤原因为泌尿外科手术6例,妇产科手术2例,普外科手术1例。9例患者均行回肠代输尿管术,术后留置输尿管内双J管1~2个月。对所有入组患者进行门诊及电话随访,了解其并发症及术后肾功能情况,采用Clavien并发症分级系统对术后并发症进行分级。结果:9例手术均顺利完成,手术时间为203~394 min,平均(278.1±68.8) min,估计出血量为10~1 000 mL(中位数200 mL), 平均住院时间为(16.8±7.5) d。4例(44.4%)患者发生术后并发症,均为Clavien Ⅰ~Ⅱ级轻微并发症,其中不全肠梗阻3例(33.3%), 近端吻合口漏1例(11.1%)。中位随访时间11个月,8例(88.9%)患者术后肌酐水平较术前相比有所改善或稳定。随访过程中3例(33.3%)患者出现轻度肾积水,但无明显症状亦不需特殊处理;1例(11.1%)患者发生短期泌尿系感染,需口服抗生素治疗;未发现代谢性并发症发生。结论:回肠代输尿管术是一种可选择的尿路重建方式,尤其对难治性医源性长段输尿管损伤的治疗效果满意,其远期临床疗效仍需进一步观察。

本文引用格式

刘沛 , 吴鑫 , 朱雨泽 , 唐琦 , 方冬 , 李学松△ , 郝金瑞 , 周利群 . 回肠代输尿管术治疗医源性长段输尿管损伤[J]. 北京大学学报(医学版), 2015 , 47(4) : 643 -647 . DOI: 10.3969/j.issn.1671-167X.2015.04.019

Abstract

Objective:To investigate the efficacy of ileal ureteric replacement in the treatment of iatrogenic long segment ureteric injuries. Methods: The hospital records of 9 cases with iatrogenic long segment ureteric injuries during Aug. 2010 to Sept. 2014 treated with ileal ureteric replacement were retrospectively reviewed and followed-up postoperatively. The patients included 3 males and 6 females with a median age of 40 years. The length of injury segment was 13-25 cm (median 20 cm). The etiology of the iatrogenic injury was urological surgery (n=6), gynecological surgery (n=2) and general surgery (n=1), respectively. The ureter stent was removed in 1-2 month postoperatively in all the 9 cases. Results: All the operations were successful. The operation time was 203-394 min, with the average of (278.1±68.8) min. The bleeding volume was 10-1 000 mL, with the median of 200 mL. The mean length of hospital stay was (16.8±7.5) days. Four minor complications (Grade Ⅰ-Ⅱ) developed, including 3 ileus (33.3%) and 1 proximal anastomotic leakage (11.1%). The median followup time was 11 months, serum creatinine decreased or remained stable in 8 patients (88.9%). Three patients (33.3%) developed mild hydronephrosis and shorttime urinary tract infection was seen in 1 patient (11.1%). Metabolic acidosis was not detected during the followup. Conclusion: Ileal ureteric replacement is a safe and effective method in patients with complex or difficult iatrogenic long segment ureteric injuries.

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