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Journal of Peking University (Health Sciences) ›› 2026, Vol. 58 ›› Issue (2): 410-415. doi: 10.19723/j.issn.1671-167X.2026.02.029

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郭芷均, 俎明, 马超, 张贺军, 张静, 丁士刚*()   

  • Received:2024-04-02 Online:2026-04-18 Published:2026-01-09
  • Contact: 丁士刚

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  • R735.2

Figure 1

Example of nodularity (under white light imaging)"

Table 1

Clinical risk factors of patients with missed SMEGC"

Clinical characters Concomitant patients (n=39) Missed patients (n=18) P value
Gender, n (%) >0.999
  Male 31 (79.5) 14 (77.8)
  Female 8 (20.5) 4 (22.2)
Age/year, $\bar x \pm s$ 67.62±12.43 65.50±7.15 0.505
Smoking history, n (%) 0.771
  No 23 (59.0) 12 (66.7)
  Yes 16 (41.0) 6 (33.3)
Drinking history, n (%) 0.365
  No 24 (61.5) 14 (77.8)
  Yes 15 (38.5) 4 (22.2)
Family history of cancer, n (%) >0.999
  No 32 (82.1) 15 (83.3)
  Yes 7 (17.9) 3 (16.7)
History of other cancer, n (%) 0.704
  No 32 (82.1) 16 (88.9)
  Yes 7 (17.9) 2 (11.1)
Helicobacter pylori infection, n (%) 0.554
  Negative 18 (51.4) 7 (38.9)
  Positive 10 (28.6) 8 (44.4)
  Negative after eradication 7 (20.0) 3 (16.7)
  Unknowna 4 0
Xanthoma, n (%) >0.999
  No 34 (89.5) 17 (94.4)
  Yes 4 (10.5) 1 (5.6)
  Unknowna 1 0
OLGA, n (%) 0.266
  0 1 (2.9) 0 (0.0)
  Ⅰ-Ⅱ 27 (79.4) 10 (62.5)
  Ⅲ-Ⅳ 6 (17.6) 6 (37.5)
  Unknowna 5 2
OLGIM, n (%) 0.826
  0 1 (2.9) 0 (0.0)
  Ⅰ-Ⅱ 24 (68.6) 10 (62.5)
  Ⅲ-Ⅳ 10 (28.5) 6 (37.5)
  Unknowna 4 2
Autoimmune gastritis, n (%) >0.999
  No 37 (94.9) 18 (100.0)
  Yes 2 (5.1) 0 (0.0)
Number of SMEGC lesion, $\bar x \pm s$ 2.31±0.73 2.39±0.78 0.704

Table 2

Endoscopic pathological characteristics of lesions in SMEGC"

Characters Concomitant lesions(n=112) Missed lesions(n=21) P value of univariate analysis Multivariate analysis
P value OR(95%CI)
Longitudinal location, n (%) 0.586
  Upper 26 (23.2) 5 (23.8)
  Middle 31 (27.7) 8 (38.1)
  Lower 55 (49.1) 8 (38.1)
Cross-sectional location, n (%) 0.081
  Lesser curvature 49 (43.8) 10 (47.6)
  Greater curvature 29 (25.9) 2 (9.5)
  Anterior wall 15 (13.3) 1 (4.8)
  Posterior wall 19 (17.0) 8 (38.1)
Macroscopic types, n (%) 0.514
  Elevated 49 (43.8) 7 (33.3)
  Flat 33 (29.5) 9 (42.9)
  Depressed 30 (26.7) 5 (23.8)
Ulcer, n (%) >0.999
  No 88 (78.6) 17 (81.0)
  Yes 24 (21.4) 4 (19.0)
Nodularity, n (%) 0.011
  No 97 (86.6) 13 (61.9)
  Yes 15 (13.4) 8 (38.1) 0.001 7.40 (2.20, 24.88)
Redness, n (%) 0.560
  No 91 (81.3) 16 (76.2)
  Yes 21 (18.7) 5 (23.8)
Size/mm, $\bar x \pm s$ 13.51±10.72 8.56±7.01 0.044 0.024 0.92 (0.86, 0.99)
Depth, n (%) 0.243
  Mucosa 86 (76.8) 19 (90.5)
  Submucosa 26 (23.2) 2 (9.5) 0.229 0.37 (0.07, 1.88)
Degree of differentiation, n (%) 0.566
  Differentiated 88 (78.6) 18 (85.7)
  Undifferentiated 24 (21.4) 3 (14.3) 0.494 0.61 (0.15, 2.53)
Lymphatic vascular invasion, n (%) >0.999
  No 109 (97.3) 21 (100.0)
  Yes 3 (2.7) 0 (0.0)

Table 3

Contingency table of longitudinal location of detected and missed lesions"

Characters Missed lesions Total
Upper Middle Lower
Concomitant lesions
  Upper 1 1 2 4
  Middle 2 4 2 8
  Lower 1 2 3 6
Total 4 7 7 18

Table 4

Contingency table of cross-sectional location of detected and missed lesions"

Characters Missed lesions Total
Lesser curvature Greater curvature Anterior walla Posterior wall
Concomitant lesions
  Lesser curvature 4 0 0 2 6
  Greater curvature 3 1 0 1 5
  Anterior wall 0 0 0 1 1
  Posterior wall 3 1 0 2 6
Total 10 2 0 6 18

Table 5

Contingency table of macroscopic types of detected and missed lesions"

Characters Missed lesions Total
Elevated Flat Depressed
Concomitant lesions
  Elevated 4 2 2 8
  Flat 1 5 2 8
  Depressed 1 1 0 2
Total 6 8 4 18
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