Email Alert | RSS

Journal of Peking University (Health Sciences) ›› 2020, Vol. 52 ›› Issue (6): 1048-1055. doi: 10.19723/j.issn.1671-167X.2020.06.010

Previous Articles     Next Articles

Depression and anxiety in patients with psoriatic arthritis: Prevalence and associated factors

Yan GENG,Zhi-bo SONG,Xiao-hui ZHANG,Xue-rong DENG,Yu WANG,Zhuo-li ZHANG()   

  1. Department of Rheumatology and Clinical Immunology, Peking University First Hospital, Beijing 100034, China
  • Received:2020-08-03 Online:2020-12-18 Published:2020-12-13
  • Contact: Zhuo-li ZHANG E-mail:zhuoli.zhang@126.com
  • Supported by:
    National Natural Science Foundation of China(81901646);National Natural Science Foundation of China(81771740);National Natural Science Foundation of China(81971524);Youth Clinical Research Project of Peking University First Hospital(2019CR28)

RICH HTML

   

PDF (PC)

Abstract:

Objective: To determine the prevalence of depression and anxiety in patients with psoriatic arthritis (PsA), to investigate whether there is a difference in the prevalence of depression and anxiety between PsA and rheumatoid arthritis (RA) patients and to identify associated risk factors for depression and anxiety in PsA patients. Methods: PsA and RA patients who visited Department of Rheumatology and Clinical Immunology in Peking University First Hospital from May 2018 to Sep 2019 were recruited. Self-rating anxiety scale and self-rating depression scale were surveyed and compared between PsA and RA patients. Demographics and clinical features including age, gender, disease duration, disease activity score, psoriasis area and severity index (PASI), and medical application were collected. Power Doppler and grey-scale ultrasound of joints, tenosynovitis and enthesis were performed. Multivariate Logistic regression was used to identify the factors associated with mood disorders and the odds ratio of depression and anxiety between the PsA and RA patients. Results: Among the 114 enrolled PsA patients, 37 (32.5%) had mood disorders, in which 36 (31.6%) with depression and 15 (13.2%) with anxiety. Compared with 201 RA patients, PsA patients showed greater odds for depression [adjusted OR (95%CI): 2.7 (1.1-6.4)]. Depression was more often observed in the PsA than in the RA patients (31.6% vs. 18.9%, P=0.011). The similar trend for anxiety was also observed, although the difference was insignificant (13.2% vs. 8.5%, P=0.185). Age (OR=0.95, P=0.008), psoriasis duration (OR=0.94, P=0.018), pain visual analogue scale (OR=1.47, P=0.011), PASI score (OR=1.07, P=0.007) and presence of ultrasound enthesitis (OR=4.13, P=0.009) were identified as factors associated with depression in the PsA patients. PASI score (OR=1.07, P=0.001) was identified as associated factor for anxiety in the PsA patients. Conclusion: The prevalence of depression and anxiety is elevated in PsA patients. Depression is significantly more prevalent in PsA patients than in RA patients. Younger age, shorter psoriasis duration, worse pain and presence of ultrasound enthesitis are associated with depression, while severe psoriasis rash is associated with both depression and anxiety in PsA patients.

Key words: Psoriatic arthritis, Depression, Anxiety, Prevalence

CLC Number: 

  • R593.2

Table 1

Comparisons of clinical features and psychological disorders between PsA and RA patients"

Items PsA (n=114) RA (n=201) P
Female 55 (48.2) 166 (82.6) <0.001
Age/years 47.6±13.5 49.5±13.0 0.222
Disease duration/years 14.0 (7.0, 24.3) 3.4 (1.0, 10.0) <0.001
TJC 28 3.0 (1.0, 8.0) 2.0 (0.0, 6.5) 0.253
SJC 28 2.0 (0.0, 6.0) 1.0 (0.0, 3.5) 0.054
ESR/(mm/h) 11.5 (5.0, 27.3) 21.0 (10.0, 40.0) <0.001
CRP/(mg/L) 5.5 (2.0, 15,6) 6.1 (2.6, 14.8) 0.176
PGA (0-10) 4.0 (2.0, 6.0) 3.0 (2.0, 6.0) 0.276
EGA (0-10) 3.0 (2.0, 5.0) 2.0 (1.0, 5.0) 0.124
Pain VAS (0-10) 3.8 (2.0, 5.0) 3.0 (1.3, 5.0) 0.615
DAS28-CRP 3.4±1.5 3.6±1.6 0.419
SDAI 14.1 (7.3, 24.4) 10.6 (5.6, 24.0) 0.067
HAQ 1.0 (0.0, 8.0) 4.0 (0.5, 15.0) 0.001
PASI 3.2 (0.8, 9.4) 0.0 (0.0, 0.0) <0.001
Mood disorder
Depression 36 (31.6) 38 (18.9) <0.001
Anxiety 15 (13.2) 17 (8.5) 0.185
Cigarette smoking <0.001
Non-smokers 76 (66.7) 170 (84.6)
Ex-smokers 14 (12.3) 15 (7.5)
Current smokers 24 (21.1) 16 (8.0)
csDMARDs used <0.001
csDMARDs-naive 14 (12.3) 66 (32.8)
Single csDMARDs 80 (70.2) 49 (24.4)
Combined csDMARDs 20 (17.5) 86 (42.8)
Biological DMARDs used 2 (1.8) 4 (2.0) 0.882
Metabolic syndrome 38 (33.3) 19 (9.5) <0.001

Table 2

The factors for associated with depression (PsA vs. RA odds ratio, Logistic regression)"

Items OR 95%CI P
PsA vs. RA 2.70 1.14-6.44 0.025
Age 0.97 0.95-0.99 0.004
Disease duration 0.94 0.91-0.98 0.002
SDAI 1.00 0.98-1.03 0.977
HAQ 1.04 1.01-1.08 0.031
PASI 1.06 1.02-1.11 0.009

Table 3

Comparisons of clinical and ultrasonographic features between PsA patients with depression and without depression"

Items PsA with depression (n=36) PsA without depression (n=78) P
Female 18 (50.0) 37 (47.40) 0.799
Age/years 41.6±14.5 50.4±12.1 0.001
Disease duration of PsO/years 10.0 (5.3, 15.8) 15.5 (7.8, 29.3) 0.048
Disease duration of PsA/years 3.5 (1.0, 9.5) 3.3 (1.2, 8.5) 0.932
TJC 68 3.0 (1.3, 9.8) 2.5 (1.0, 8.0) 0.495
SJC 66 3.0 (0.3, 6.0) 2.0 (0.0, 5.3) 0.641
Pain VAS (0-10) 4.0 (3.0, 6.0) 3.0 (2.0, 5.0) 0.015
PGA (0-10) 5.0 (3.0, 6.8) 4.0 (2.0, 5.0) 0.059
EGA (0-10) 3.0 (2.0, 5.0) 3.0 (1.5, 4.3) 0.207
CRP/(mg/L) 5.7 (2.4, 20.3) 4.6 (1.9, 15.6) 0.592
ESR/(mm/h) 12.5 (7.0, 27.0) 11.0 (5.0, 28.3) 0.676
DAPSA 17.4 (8.7, 27.7) 14.2 (7.8, 24.4) 0.239
HAQ 2.5 (0.0, 8.8) 1.0 (0.0, 7.3) 0.305
PSAI 4.4 (1.2, 29.4) 2.6 (0.7, 7.7) 0.018
Ultrasonographic feathers
Synovitis GS total score 1.5 (0.0, 3.8) 1.5 (0.0, 4.0) 0.957
Synovitis PD total score 0.0 (0.0, 1.0) 0.0 (0.0, 2.0) 0.414
Tenosynovitis GS total score 0.0 (0.0, 2.0) 0.0 (0.0, 2.0) 0.279
Tenosynovitis PD total score 0.0 (0.0, 1.0) 0.0 (0.0, 1.0) 0.528
Presence of enthesitis 23 (63.9) 33 (42.3) 0.032
Bone erosion 16 (44.4) 32 (41.0) 0.731
csDMARDs used 0.165
csDMARDs-naive 4 (11.1) 10 (11.8)
Single csDMARD 22 (61.1) 58 (74.4)
Combined csDMARDs 10 (27.8) 10 (12.8)
Biological DMARDs used 1 (2.8) 1 (1.3) 0.534
NSAIDs used 12 (33.3) 19 (24.4) 0.317
BMI/(kg/m2) 23.2±2.8 24.0±3.0 0.178
Waist circumference/cm 82.3±10.5 84.6±8.5 0.250
Onychosis 16 (44.6) 53 (62.4) 0.069
Ophthalmitis 2 (5.6) 1 (1.3) 0.234
Metabolic syndrome 8 (22.2) 30 (38.5) 0.087
Cigarette smoking 0.902
Non-smoker 23 (63.9) 53 (67.9)
Ex-smoker 5 (13.9) 9 (11.5)
Current smoker 8 (22.2) 16 (20.5)
Family history of PsO/PsA 17 (47.2) 23 (29.5) 0.065

Table 4

Comparisons of clinical and ultrasonographic features between PsA patients with anxiety and without anxiety"

Items PsA with anxiety (n=15) PsA without anxiety (n=99) P
Female 8 (53.3) 47 (47.5) 0.672
Age/years 42.8±16.8 48.3±12.8 0.140
Disease duration of PsO/years 11.0 (4.0, 20.0) 14.0 (8.0, 26.0) 0.401
Disease duration of PsA/years 7.0 (1.0, 12.0) 3.0 (1.0, 8.0) 0.233
TJC 68 2.0 (0.0, 10.0) 3.0 (1.0, 8.0) 0.939
SJC 66 2.0 (0.0, 6.0) 2.0 (0.0, 5.0) 0.963
Pain VAS (0-10) 3.0 (3.0, 6.0) 4.0 (2.0, 5.0) 0.343
PGA (0-10) 3.0 (2.0, 6.0) 4.0 (2.0, 6.0) 0.922
EGA (0-10) 2.0 (2.0, 5.0) 3.0 (2.0, 5.0) 0.806
CRP/(mg/L) 5.5 (1.3, 11.9) 5.4 (2.0, 15.8) 0.672
ESR/(mm/h) 11.0 (5.0, 21.0) 12.0 (5.0, 29.0) 0.540
DAPSA 14.5 (5.1, 31.5) 15.7 (8.3, 24.4) 0.983
HAQ 3.0 (0.0, 14.0) 1.0 (0.0, 7.0) 0.263
PSAI 7.6 (0.6, 39.0) 3.0 (0.8, 8.4) 0.047
Ultrasonographic feathers
Synovitis GS total score 0.0 (0.0, 2.0) 2.0 (0.0, 4.0) 0.147
Synovitis PD total score 0.0 (0.0, 0.0) 0.0 (0.0, 2.0) 0.270
Tenosynovitis GS total score 0.0 (0.0, 2.0) 0.0 (0.0, 2.0) 0.608
Tenosynovitis PD total score 0.0 (0.0, 0.0) 0.0 (0.0, 1.0) 0.200
Presence of enthesitis 7 (46.7) 49 (49.5) 0.838
Bone erosion 5 (33.3) 43 (43.4) 0.460
csDMARDs used 0.068
csDMARDs-naive 2 (13.3) 12 (12.1)
Single csDMARDs 7 (46.7) 73 (73.7)
Combined csDMARDs 6 (40.0) 14 (14.1)
Biological DMARDs used 1 (6.7) 1 (1.0) 0.617
NSAIDs used 3 (20.0) 28 (28.3) 0.718
BMI/(kg/m2) 24.3±2.4 23.6±3.0 0.417
Waist circumference/cm 84.7±11.8 83.7±8.8 0.734
Onychosis 6 (40.0) 58 (58.6) 0.176
Ophthalmitis 0 3 (3.0) 0.652
Metabolic syndrome 6 (40.0) 32 (32.3) 0.557
Cigarette smoking 0.266
Non-smokers 11 (73.3) 65 (65.7)
Ex-smokers 3 (20.0) 11 (11.1)
Current smokers 1 (6.7) 23 (23.2)
Family history of PsO/PsA 7 (46.7) 33 (33.3) 0.313

Table 5

The associated factors for depression/anxiety in PsA (multivariate Logistic regression)"

Items OR 95%CI P
Associated factors for depression
Age 0.95 0.91-0.99 0.008
Disease duration 0.94 0.90-0.99 0.018
Pain VAS 1.47 1.09-1.98 0.011
PASI 1.07 1.02-1.13 0.007
Presence of ultrasound enthesitis 4.13 1.42-12.05 0.009
Associated factor for anxiety
PASI 1.07 1.03-1.12 0.001
[1] Gladman DD, Antoni C, Mease P, et al. Psoriatic arthritis: Epidemiology, clinical features, course, and outcome[J]. Ann Rheum Dis, 2005,64(Suppl 2):14-17.
[2] Giacomelli R, Gorla R, Trotta F, et al. Quality of life and unmet needs in patients with inflammatory arthropathies: Results from the multicentre, observational RAPSODIA study[J]. Rheumatology (Oxford), 2015,54(5):792-797.
doi: 10.1093/rheumatology/keu398
[3] Wu JJ, Penfold RB, Primatesta P, et al. The risk of depression, suicidal ideation and suicide attempt in patients with psoriasis, psoriatic arthritis or ankylosing spondylitis[J]. J Eur Acad Dermatol Venereol, 2017,31(7):1168-1175.
doi: 10.1111/jdv.14175 pmid: 28214371
[4] Kamalaraj N, El-Haddad C, Hay P, et al. Systematic review of depression and anxiety in psoriatic arthritis[J]. Int J Rheum Dis, 2019,22(6):967-973.
doi: 10.1111/1756-185X.13553 pmid: 31025820
[5] Freire M, Rodriguez J, Moller I, et al. Prevalence of symptoms of anxiety and depression in patients with psoriatic arthritis attending rheumatology clinics[J]. Reumatol Clin, 2011,7(1):20-26.
doi: 10.1016/j.reuma.2010.03.003
[6] Husted JA, Gladman DD, Farewell VT, et al. Health-related quality of life of patients with psoriatic arthritis: A comparison with patients with rheumatoid arthritis[J]. Arthritis Rheum, 2001,45(2):151-158.
doi: 10.1002/1529-0131(200104)45:2<151::AID-ANR168>3.0.CO;2-T pmid: 11324779
[7] Taylor W, Gladman D, Helliwell P, et al. Classification criteria for psoriatic arthritis: Development of new criteria from a large international study[J]. Arthritis Rheum, 2006,54(8):2665-2673.
pmid: 16871531
[8] Arnett FC, Edworthy SM, Bloch DA, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis[J]. Arthritis Rheum, 1988,31(3):315-324.
pmid: 3358796
[9] Aletaha D, Neogi T, Silman AJ, et al. 2010 rheumatoid arthritis classification criteria: An American College of Rheumatology / European League Against Rheumatism collaborative initiative[J]. Ann Rheum Dis, 2010,69(9):1580-1588.
doi: 10.1136/ard.2010.138461 pmid: 20699241
[10] Zung WW. The depression status inventory: An adjunct to the self-rating depression scale[J]. J Clin Psychol, 1972,28(4):539-543.
doi: 10.1002/1097-4679(197210)28:4<539::aid-jclp2270280427>3.0.co;2-s pmid: 5080837
[11] Bruce B, Fries JF. The Health Assessment Questionnaire (HAQ)[J]. Clin Exp Rheum, 2005,23(5 Suppl 39):14-18.
[12] Schmitt J, Wozel G. The psoriasis area and severity index is the adequate criterion to define severity in chronic plaque-type psoriasis[J]. Dermatology, 2005,210(3):194-199.
doi: 10.1159/000083509 pmid: 15785046
[13] Makinen H, Kautiainen H, Hannonen P, et al. Disease activity score 28 as an instrument to measure disease activity in patients with early rheumatoid arthritis[J]. J Rheum, 2007,34(10):1987-1991.
pmid: 17611990
[14] Smolen JS, Breedveld FC, Schiff MH, et al. A simplified disease activity index for rheumatoid arthritis for use in clinical practice[J]. Rheumatology (Oxford), 2003,42(2):244-257.
doi: 10.1093/rheumatology/keg072
[15] Smolen JS, Schoels M, Aletaha D. Disease activity and response assessment in psoriatic arthritis using the disease activity index for psoriatic arthritis (DAPSA). A brief review[J]. Clin Exp Rheum, 2015,33(5 Suppl 93):48-50.
[16] Lu B, Rho YH, Cui J, et al. Associations of smoking and alcohol consumption with disease activity and functional status in rheumatoid arthritis[J]. J Rheum, 2014,41(1):24-30.
doi: 10.3899/jrheum.130074 pmid: 24293566
[17] Alberti KG, Zimmet P, Shaw J. Metabolic syndrome: A new world-wide definition. A consensus statement from the International Diabetes Federation[J]. Diabet Med, 2006,23(5):469-480.
pmid: 16681555
[18] Wakefield RJ, Balint PV, Szkudlarek M, et al. Musculoskeletal ultrasound including definitions for ultrasonographic pathology[J]. J Rheum, 2005,32(12):2485-2487.
pmid: 16331793
[19] Szkudlarek M, Court-Payen M, Strandberg C, et al. Power Doppler ultrasonography for assessment of synovitis in the metacarpophalangeal joints of patients with rheumatoid arthritis: A comparison with dynamic magnetic resonance imaging[J]. Arthritis Rheum, 2001,44(9):2018-2023.
doi: 10.1002/1529-0131(200109)44:9<2018::AID-ART350>3.0.CO;2-C pmid: 11592362
[20] Naredo E, D'Agostino MA, Wakefield RJ, et al. Reliability of a consensus-based ultrasound score for tenosynovitis in rheumatoid arthritis[J]. Ann Rheum Dis, 2013,72(8):1328-1334.
doi: 10.1136/annrheumdis-2012-202092
[21] Michelsen B, Kristianslund EK, Sexton J, et al. Do depression and anxiety reduce the likelihood of remission in rheumatoid arthritis and psoriatic arthritis? Data from the prospective multicentre NOR-DMARD study[J]. Ann Rheum Dis, 2017,76(11):1906-1910.
doi: 10.1136/annrheumdis-2017-211284 pmid: 28733473
[22] Lowe B, Willand L, Eich W, et al. Psychiatric comorbidity and work disability in patients with inflammatory rheumatic diseases[J]. Psychosom Med, 2004,66(3):395-402.
pmid: 15184703
[23] Baxter AJ, Scott KM, Vos T, et al. Global prevalence of anxiety disorders: A systematic review and meta-regression[J]. Psychol Med, 2013,43(5):897-910.
doi: 10.1017/S003329171200147X
[24] Zhao SS, Miller N, Harrison N, et al. Systematic review of mental health comorbidities in psoriatic arthritis[J]. Clin Rheumatol, 2020,39(1):217-225.
doi: 10.1007/s10067-019-04734-8 pmid: 31486931
[25] Zusman EZ, Howren AM, Park JYE, et al. Epidemiology of depression and anxiety in patients with psoriatic arthritis: A systema-tic review and meta-analysis [J/OL]. Semin Arthritis Rheum, (2020-02-13) [2020-05-15]. doi: 10.1016/j.semarthrit.2020.02.001.
[26] Bacconnier L, Rincheval N, Flipo RM, et al. Psychological distress over time in early rheumatoid arthritis: Results from a longitudinal study in an early arthritis cohort[J]. Rheumatology (Oxford), 2015,54(3):520-527.
doi: 10.1093/rheumatology/keu371
[27] Overman CL, Bossema ER, van Middendorp H, et al. The prospective association between psychological distress and disease activity in rheumatoid arthritis: A multilevel regression analysis[J]. Ann Rheum Dis, 2012,71(2):192-197.
doi: 10.1136/annrheumdis-2011-200338
[28] Rosenblat JD, Cha DS, Mansur RB, et al. Inflamed moods: A review of the interactions between inflammation and mood disorders[J]. Prog Neuropsychopharmacol Biol Psychiatry, 2014(53):23-34.
[29] Dowlatshahi EA, Wakkee M, Arends LR, et al. The prevalence and odds of depressive symptoms and clinical depression in psoriasis patients: A systematic review and meta-analysis[J]. J Invest Dermatol, 2014,134(6):1542-1551.
pmid: 24284419
[30] McDonough E, Ayearst R, Eder L, et al. Depression and anxiety in psoriatic disease: Prevalence and associated factors[J]. J Rheum, 2014,41(5):887-896.
doi: 10.3899/jrheum.130797 pmid: 24692521
[31] Riente L, Carli L, Delle Sedie A. Ultrasound imaging in psoriatic arthritis and ankylosing spondylitis[J]. Clin Exp Rheum, 2014,32(1 Suppl 80):26-33.
[32] Freeston JE, Coates LC, Helliwell PS, et al. Is there subclinical enthesitis in early psoriatic arthritis? A clinical comparison with power doppler ultrasound[J]. Arthritis Care Res (Hoboken), 2012,64(10):1617-1621.
doi: 10.1002/acr.21733
[33] Miller AH, Haroon E, Raison CL, et al. Cytokine targets in the brain: Impact on neurotransmitters and neurocircuits[J]. Depress Anxiety, 2013,30(4):297-306.
pmid: 23468190
[34] Dregan A, Matcham F, Harber-Aschan L, et al. Common mental disorders within chronic inflammatory disorders: A primary care database prospective investigation[J]. Ann Rheum Dis, 2019,78(5):688-695.
pmid: 30846444
[35] Sinnathurai P, Buchbinder R, Hill C, et al. Comorbidity in pso-riatic arthritis and rheumatoid arthritis[J]. Intern Med J, 2018,48(11):1360-1368.
doi: 10.1111/imj.14046 pmid: 30047189
[1] Xiaohuan SONG, Guiying LUO, Jieyu WANG, Yuedi JIA, Fei JIANG, Mengli ZHU, Danni WANG. Correlational research on body fat rate and skeletal muscle rate with depression in the population of assisted reproduction [J]. Journal of Peking University (Health Sciences), 2026, 58(2): 319-326.
[2] Xin CHEN, Junting YANG, Jinxin GUO, Shuya LI, Zhike LIU, Yingliang ZHU, Fengjuan LI, Siyan ZHAN, Juanjuan GUO. Prevalence characteristics of autoimmune thyroid disease in women aged 10-59 years in Qingdao City from 2022 to 2024 [J]. Journal of Peking University (Health Sciences), 2025, 57(3): 507-513.
[3] Abudurexiti ANARGUL, Yinghao SONG, Xiaojin YAN, Yongkang GAO, Bo LIU, Gang HU. Disease burden and future trend predictions of age-related hearing loss in China and worldwide from 1990 to 2021 [J]. Journal of Peking University (Health Sciences), 2025, 57(3): 545-553.
[4] Fangru LIN, Zhihui TANG. Correlation analysis of peri-implant health after single-tooth dental implant [J]. Journal of Peking University (Health Sciences), 2025, 57(2): 347-353.
[5] Min WANG, Qian LI. Path analysis of influencing factors of mental resilience in adolescents with depression [J]. Journal of Peking University (Health Sciences), 2024, 56(5): 809-814.
[6] Yuanyuan ZENG,Yun XIE,Daonan CHEN,Ruilan WANG. Related factors of euthyroid sick syndrome in patients with sepsis [J]. Journal of Peking University (Health Sciences), 2024, 56(3): 526-532.
[7] Huameng TANG,Dianqi YUAN,Mingxing WANG,Hanbing YANG,Chao GUO. Sequential mediating role of digital participation and health lifestyle in the relationship between socioeconomic status and depression of older adults [J]. Journal of Peking University (Health Sciences), 2024, 56(2): 230-238.
[8] Jin-hui LAI,Qi WANG,Jia-xiang JI,Ming-rui WANG,Xin-wei TANG,Ke-xin XU,Tao XU,Hao HU. Effects of delayed ureteral stents removal during the COVID-19 pandemic on the quality of life and psychological status of postoperative patients with urinary calculi [J]. Journal of Peking University (Health Sciences), 2023, 55(5): 857-864.
[9] Yong-wei LIN,Ya-lin ZHOU,Run-long ZHAO,Ya-jun XU,Yan-ping LIU. Analysis on the iron status and associated factors during the first trimester of pregnancy [J]. Journal of Peking University (Health Sciences), 2023, 55(4): 600-605.
[10] Qiang FU,Guan-ying GAO,Yan XU,Zhuo-hua LIN,You-jing SUN,Li-gang CUI. Comparative study of ultrasound and magnetic resonance imaging in the diagnosis of asymptomatic anterosuperior acetabular labrum tears [J]. Journal of Peking University (Health Sciences), 2023, 55(4): 665-669.
[11] Wen YUAN,Yi ZHANG,Li CHEN,Jia-nuo JIANG,Man-man CHEN,Jie-yu LIU,Tao MA,Qi MA,Meng-jie CUI,Tong-jun GUO,Xin-xin WANG,Yan-hui DONG,Jun MA. Association of body fat distribution with depression and social anxiety in children and adolescents: A cross-sectional study based on dual-energy X-ray detection [J]. Journal of Peking University (Health Sciences), 2023, 55(3): 429-435.
[12] Yi-hua LIU, Qing-ping YUN, Lan-chao ZHANG, Xiao-yue ZHANG, Yu-ting LIN, Fang-jing LIU, Zhi-jie ZHENG, Chun CHANG. Joint association of sedentary behavior and physical activity on anxiety tendency among occupational population in China [J]. Journal of Peking University (Health Sciences), 2022, 54(3): 490-497.
[13] SONG Zhi-bo,GENG Yan,DENG Xue-rong,ZHANG Xiao-hui,ZHANG Zhuo-li. Benefit of ultrasound in the phenotype recognition of psoriatic arthritis [J]. Journal of Peking University (Health Sciences), 2021, 53(6): 1061-1066.
[14] FAN Li-shi,GAO Min,Edwin B. FISHER,SUN Xin-ying. Factors associated with quality of life in 747 patients with type 2 diabetes in Tongzhou District and Shunyi District of Beijing [J]. Journal of Peking University (Health Sciences), 2021, 53(3): 523-529.
[15] WU Jun-hui,CHEN Hong-bo,WU Yi-qun,WU Yao,WANG Zi-jing,WU Tao,WANG Meng-ying,WANG Si-yue,WANG Xiao-wen,WANG Jia-ting,YU Huan,HU Yong-hua. Prevalence and risk factors of osteoarthritis in patients with type 2 diabetes in Beijing, China from 2015 to 2017 [J]. Journal of Peking University (Health Sciences), 2021, 53(3): 518-522.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright © Journal of Peking University (Health Sciences), All Rights Reserved.
Powered by Beijing Magtech Co. Ltd