Journal of Peking University(Health Sciences) ›› 2017, Vol. 49 ›› Issue (6): 1044-1049. doi: 10.3969/j.issn.1671-167X.2017.06.019

• Article • Previous Articles     Next Articles

Intravenous sedation with midazolam and propofol target controlled infusion on patients’ perioperative anxiety under the mandibular third molar extraction

WANG Tian-jiao, LIU Yu△, GUAN Ming△   

  1. (Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology & National Engi-neering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China)
  • Online:2017-12-18 Published:2017-12-18
  • Contact: LIU Yu, GUAN Ming E-mail:liuyu4145@sina.com, guanming0128@vip.sina.com

Abstract: Objective: To evaluate whether midazolam with propofol target controlled infusion (TCI) intravenous sedation during the mandibular third molar extraction influences patients’ perioperative anxiety. Methods: The subjects were patients who planned to undergo the mandibular third molar extraction in Peking University School and Hospital of Stomatology, whose state anxiety inventory (SAI) scores were≥38 at the initial visit. They were divided into intravenous sedation group (IVS) and local anesthesia group (LA) on the basis of the planned intravenous sedation. Each group was divided into two subgroups according to the overall SAI scores at the initial visit: IVS-Ⅰ, LA-Ⅰ(SAI: 38-50) and IVS-Ⅱ, LA-Ⅱ (SAI: 51-80). The anxiety before and after the surgery was evaluated by the SAI scores at the initial visit (T1), before surgery (T2) and 7 days after surgery (T3). The anxiety during the surgery was evaluated by the heart rate, blood pressure and visual analogue scale (VAS) scores. Results: There were no significant differences on SAI at T1, T2, and T3 in the two groups (P>0.05). The heart rate, blood pressure and VAS pain scores of IVS group were significantly lower than those of LA group during the surgery (P<0.001). Conclusion: Intravenous sedation with midazolam and propofol TCI was effective on the patients’ anxiety during the third molar extraction, which successfully made the patients more comfortable and their heart rate, blood pressure and oxygen saturation more stable during the surgery. But there were no significant differences on the patients’ anxiety at the initial visit (T1), before surgery (T2) and 7 days after surgery (T3) according to the SAI scores in the two groups.

Key words: Conscious sedation, Anesthesia, intravenous, Anxiety, Molar, third, Tooth extraction

CLC Number: 

  • R614.24
[1] Jin-hui LAI,Qi WANG,Jia-xiang JI,Ming-rui WANG,Xin-wei TANG,Ke-xin XU,Tao XU,Hao HU. Effects of delayed ureteral stents removal during the COVID-19 pandemic on the quality of life and psychological status of postoperative patients with urinary calculi [J]. Journal of Peking University (Health Sciences), 2023, 55(5): 857-864.
[2] Wen YUAN,Yi ZHANG,Li CHEN,Jia-nuo JIANG,Man-man CHEN,Jie-yu LIU,Tao MA,Qi MA,Meng-jie CUI,Tong-jun GUO,Xin-xin WANG,Yan-hui DONG,Jun MA. Association of body fat distribution with depression and social anxiety in children and adolescents: A cross-sectional study based on dual-energy X-ray detection [J]. Journal of Peking University (Health Sciences), 2023, 55(3): 429-435.
[3] Yi-hua LIU,Qing-ping YUN,Lan-chao ZHANG,Xiao-yue ZHANG,Yu-ting LIN,Fang-jing LIU,Zhi-jie ZHENG,Chun CHANG. Joint association of sedentary behavior and physical activity on anxiety tendency among occupational population in China [J]. Journal of Peking University (Health Sciences), 2022, 54(3): 490-497.
[4] CHEN Zhen,GU Bao-xin,TANG Yu-fang,YAN Zi-yu,NI Fang-duan,CUI Nian-hui. Constructions of the scale of difficulty in the extraction of impacted mandibular third molars by using Delphi method [J]. Journal of Peking University (Health Sciences), 2022, 54(1): 100-104.
[5] WANG Si-wen,YOU Peng-yue,LIU Yu-hua,WANG Xin-zhi,TANG Lin,WANG Mei. Efficacy of two barrier membranes and deproteinized bovine bone mineral on bone regeneration in extraction sockets: A microcomputed tomographic study in dogs [J]. Journal of Peking University (Health Sciences), 2021, 53(2): 364-370.
[6] Yi-fan WANG,Zhen FAN,Yao-bin CHENG,Yue-bo JIN,Yang HUO,Jing HE. Investigation of sleep disturbance and related factors in patients with primary Sjögren’s syndrome [J]. Journal of Peking University (Health Sciences), 2020, 52(6): 1063-1068.
[7] Yan GENG,Zhi-bo SONG,Xiao-hui ZHANG,Xue-rong DENG,Yu WANG,Zhuo-li ZHANG. Depression and anxiety in patients with psoriatic arthritis: Prevalence and associated factors [J]. Journal of Peking University (Health Sciences), 2020, 52(6): 1048-1055.
[8] Duan YI,Wei ZHU,Xiu-li MENG,Xiao-guang LIU,Shui-qing LI,Bin ZHU,Dong-lin JIA. Analysis of anxiety, depression and related factors in patients with chronic lumbocrural pain before minimally invasive surgery [J]. Journal of Peking University (Health Sciences), 2020, 52(2): 285-289.
[9] Ling GAO,Yun LIU,Xu-dong YANG. Effects of intranasal dexmedetomidine for children undergoing dental rehabilitation under general anesthesia: a double-blinded randomized controlled trial [J]. Journal of Peking University(Health Sciences), 2018, 50(6): 1078-1082.
[10] ZHAO Li-ping, ZHAN Ya-lin, HU Wen-jie, WANG Hao-jie, WEI Yi-ping, ZHEN Min, Xu Tao, LIU Yun-song. Dental implantation and soft tissue augmentation after ridge preservation in a molar site: a case report [J]. Journal of Peking University(Health Sciences), 2016, 48(6): 1090-1094.
[11] LI Dan, GUO Chuan-bin, LIU Yu, WANG En-bo. Applicational evaluation of split tooth extractions of upper molars using piezosurgery [J]. Journal of Peking University(Health Sciences), 2016, 48(4): 709-713.
[12] LEI Jie,LIU Mu-qing,FU Kai-yuan. Disturbedsleep, anxiety and stress are possible risk indicators for temporomandibular disorders with myofascialpain [J]. Journal of Peking University(Health Sciences), 2016, 48(4): 692-696.
[13] HUANG Jun-qiang, LIU Shi-yao, JIANG Jiu-hui. Therapeutic evaluation of the correction of the severe bi-maxillary protrusion cases by Tweed-Merrifield technique [J]. Journal of Peking University(Health Sciences), 2016, 48(3): 555-561.
[14] ZHANG Hong-Mei, XIA Bin, WANG Jian-Hong, CHEN Xiao-Xian, GE Li-Hong. Influence of the effect of general anaesthesia and restraint during dental treatment on dental anxiety and behavior in children [J]. Journal of Peking University(Health Sciences), 2015, 47(1): 134-139.
[15] ZHAN Ya-Lin, HU Wen-Jie, ZHEN Min, Xu-Tao, Lu-Rui-Fang. Radiographic evaluation of ridge preservation after molar tooth extraction: a controlled clinical trial [J]. Journal of Peking University(Health Sciences), 2015, 47(1): 19-26.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!