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Journal of Peking University (Health Sciences) ›› 2024, Vol. 56 ›› Issue (4): 640-645. doi: 10.19723/j.issn.1671-167X.2024.04.016

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Robot-assisted laparoscopic ureteroplasty with buccal mucosa graft for complex ureteral stricture

Yicen YING1,Yicong DU1,Zhihua LI1,Yiming ZHANG1,Xinfei LI1,Bing WANG2,Peng ZHANG3,Hongjian ZHU4,Liqun ZHOU1,Kunlin YANG1,*(),Xuesong LI1,*()   

  1. 1. Department of Urology, Peking University First Hospital; Institute of Urology, Peking University; National Urological Cancer Center, Beijing 100034, China
    2. Department of Urology, Miyun Hospital, Peking University First Hospital, Beijing 101599, China
    3. Department of Urology, Emergency General Hospital, Beijing 100028, China
    4. Department of Urology, Beijing Jiangong Hospital, Beijing 100054, China
  • Received:2024-03-16 Online:2024-08-18 Published:2024-07-23
  • Contact: Kunlin YANG,Xuesong LI E-mail:yangkunlin12345@163.com;pineneedle@sina.com
  • Supported by:
    the National High Level Hospital Clinical Research Funding-Youth Clinical Research Project of Peking University First Hospital(2023YC16)

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Abstract:

Objective: To investigate the feasibility, safety and effectiveness of robot-assisted laparoscopic buccal mucosa graft ureteroplasty in the treatment of complex long proximal ureteral stricture. Methods: The clinical data of 20 patients with proximal ureteral stricture undergoing robot-assisted laparoscopic buccal mucosa graft ureteroplasty admitted to the Department of Urology, Peking University First Hospital and Beijing Jiangong Hospital from July 2022 to January 2023 were prospectively collected and analyzed. Intraoperative conditions, postoperative complications and follow-up data were also recorded and analyzed. Results: The operations under robot-assisted laparoscopy were performed successfully in all the 20 patients without conversion to traditional laparoscopic surgery or open surgery. The study included 14 males and 6 females with a mean age of (41±11) years (range: 19 to 60 years) and a mean body mass index of (24.3±3.6) kg/m2 (range: 18.2 to 31.8 kg/m2). There were 9 cases on the left side and 11 cases on the right side. The strictures of all the patients were located in the proximal segment of the ureter (including the ureteropelvic junction). The mean preoperative serum creatinine was (92.2±23.3) μmol/L (range: 49.2 to 138.9 μmol/L), and the mean length of ureteral stricture was (2.8±0.9) cm (range: 1.0 to 4.0 cm). Ten patients had previously undergone unsuccessful reconstructive surgery. During the operation, 12 patients received posteriorly augmented anastomosis with ventral onlay. The mean length of the buccal mucosa graft harvested during the operation was (3.1±0.6) cm (range: 2.0 to 4.3 cm), and the median width was 1.5 cm (range: 1.0 to 2.0 cm). The omentum flap was used to wrap the reconstructed ureteral segment in all the 20 cases. The median operative time was 154 min (range: 113 to 300 min), and the median estimated blood loss was 45 mL (range: 0 to 100 mL). The median postoperative hospital stay was 4 d (range: 4 to 14 d). The mean postoperative follow-up time was (15.0±1.7) months (range: 12.5 to 17.9 months), and the surgical success rate was 100.0% in this study. After surgery, 11 patients reported mild discomfort at the oral donor site, 2 patients deve-loped urinary tract infection, and no postoperative complications were reported in the other 7 patients. The mean serum creatinine was (90.9±23.9) μmol/L (range: 60.0 to 153.0 μmol/L) six months after surgery. Conclusion: Robot-assisted laparoscopic buccal mucosa graft ureteroplasty for the treatment of complex long proximal ureteral stricture has satisfactory efficacy without severe complications, which has shown good feasibility, safety and effectiveness. However, large sample studies and long-term follow-up are still needed to evaluate its long-term efficacy.

Key words: Robotic surgical procedures, Ureteral stricture, Buccal mucosa, Reconstructive surgical procedures

CLC Number: 

  • R693.2

Figure 1

Surgical procedure of robot-assisted buccal mucosa graft ureteroplasty A, the location of the ureteral stricture; B, the incision of the ureteral stricture; C, posteriorly augmented anastomosis; D, the harvesting process of buccal mucosa graft; E, the harvested buccal mucosa graft; F, suturing of buccal incision; G, the graft was sewn with running sutures; H, the greater omentum was wrapped around the reconstructed ureteral segment."

Figure 2

Preoperative and postoperative urography and the postoperative ureteroscopy of robot-assisted buccal mucosa graft ureteroplasty A, preoperative urography showed the location of the ureteral stricture (as indicated by the arrow); B, postoperative urography showed no obstruction (as indicated by the arrow) and relieved hydronephrosis; C, postoperative ureteroscopy showed the buccal mucosa graft (as indicated by the arrow) survived well without ureteral stenosis."

1 Li X , Qiao J , Xiong S , et al. The surgical outcomes of reconstruction for the treatment of ureteral stricture after holmium laser lithotripsy: The comprehensive experiences[J]. Asian J Surg, 2022, 45 (12): 2713- 2718.
doi: 10.1016/j.asjsur.2022.03.018
2 Elbers JR , Rodríguez Socarrás M , Rivas JG , et al. Robotic repair of ureteral strictures: Techniques and review[J]. Curr Urol Rep, 2021, 22 (8): 39.
doi: 10.1007/s11934-021-01056-8
3 Knight RB , Hudak SJ , Morey AF . Strategies for open reconstruction of upper ureteral strictures[J]. Urol Clin North Am, 2013, 40 (3): 351- 361.
doi: 10.1016/j.ucl.2013.04.005
4 Kocot A , Kalogirou C , Vergho D , et al. Long-term results of ileal ureteric replacement: A 25-year single-centre experience[J]. BJU Int, 2017, 120 (2): 273- 279.
doi: 10.1111/bju.13825
5 Monn MF , Roth JD , Bihrle R , et al. Long term outcomes in the use of ileal ureter for radiation-induced ureteral strictures[J]. Int Urol Nephrol, 2018, 50 (8): 1375- 1380.
doi: 10.1007/s11255-018-1904-z
6 Roth JD , Monn MF , Szymanski KM , et al. Ureteral reconstruction with ileum: Long-term follow-up of renal function[J]. Urology, 2017, 104, 225- 229.
doi: 10.1016/j.urology.2017.02.026
7 Eisenberg ML , Lee KL , Zumrutbas AE , et al. Long-term outcomes and late complications of laparoscopic nephrectomy with renal autotransplantation[J]. J Urol, 2008, 179 (1): 240- 243.
doi: 10.1016/j.juro.2007.08.135
8 Tran G , Ramaswamy K , Chi T , et al. Laparoscopic nephrectomy with autotransplantation: Safety, efficacy and long-term durability[J]. J Urol, 2015, 194 (3): 738- 743.
doi: 10.1016/j.juro.2015.03.089
9 Yang K , Fan S , Wang J , et al. Robotic-assisted lingual mucosal graft ureteroplasty for the repair of complex ureteral strictures: Technique description and the medium-term outcome[J]. Eur Urol, 2022, 81 (5): 533- 540.
doi: 10.1016/j.eururo.2022.01.007
10 Lee Z , Lee M , Koster H , et al. A multi-institutional experience with robotic ureteroplasty with buccal mucosa graft: An updated analysis of intermediate-term outcomes[J]. Urology, 2021, 147, 306- 310.
doi: 10.1016/j.urology.2020.08.003
11 Liang C , Wang J , Hai B , et al. Lingual mucosal graft ureteroplasty for long proximal ureteral stricture: 6 years of experience with 41 cases[J]. Eur Urol, 2022, 82 (2): 193- 200.
doi: 10.1016/j.eururo.2022.05.006
12 Wang J , Li Z , Fan S , et al. Robotic ureteroplasty with appendiceal onlay flap: An update on the outcomes of 18-month follow-up[J]. Transl Androl Urol, 2022, 11 (1): 20- 29.
doi: 10.21037/tau-21-840
13 Sterling J , Daneshvar M , Nikolavsky D . Transurethral ventral inlay buccal mucosa graft urethroplasty: Technique and intermediate outcomes[J]. BJU Int, 2023, 132 (1): 109- 111.
doi: 10.1111/bju.16007
14 Lumen N , Vierstraete-Verlinde S , Oosterlinck W , et al. Buccal versus lingual mucosa graft in anterior urethroplasty: A prospective comparison of surgical outcome and donor site morbidity[J]. J Urol, 2016, 195 (1): 112- 117.
doi: 10.1016/j.juro.2015.07.098
15 Naude JH . Buccal mucosal grafts in the treatment of ureteric lesions[J]. BJU Int, 1999, 83 (7): 751- 754.
doi: 10.1046/j.1464-410x.1999.00019.x
16 Kroepfl D , Loewen H , Klevecka V , et al. Treatment of long ureteric strictures with buccal mucosal grafts[J]. BJU Int, 2010, 105 (10): 1452- 1455.
doi: 10.1111/j.1464-410X.2009.08994.x
17 Pandey A , Dican R , Beier J , et al. Buccal mucosal graft in reconstructive urology: Uses beyond urethral stricture[J]. Int J Urol, 2014, 21 (7): 732- 734.
doi: 10.1111/iju.12403
18 Zhao LC , Yamaguchi Y , Bryk DJ , et al. Robot-assisted ureteral reconstruction using buccal mucosa[J]. Urology, 2015, 86 (3): 634- 638.
doi: 10.1016/j.urology.2015.06.006
19 Zhao LC , Weinberg AC , Lee Z , et al. Robotic ureteral reconstruction using buccal mucosa grafts: A multi-institutional experience[J]. Eur Urol, 2018, 73 (3): 419- 426.
doi: 10.1016/j.eururo.2017.11.015
20 Hefermehl LJ , Tritschler S , Kretschmer A , et al. Open ureteroplasty with buccal mucosa graft for long proximal strictures: A good option for a rare problem[J]. Investig Clin Urol, 2020, 61 (3): 316- 322.
doi: 10.4111/icu.2020.61.3.316
21 Cheng S , Fan S , Wang J , et al. Laparoscopic and robotic ureteroplasty using onlay flap or graft for the management of long proximal or middle ureteral strictures: Our experience and strategy[J]. Int Urol Nephrol, 2021, 53 (3): 479- 488.
doi: 10.1007/s11255-020-02679-5
22 葛光炬, 李恭会, 朱世斌, 等. 颊黏膜替代法在机器人辅助输尿管上段狭窄手术中的应用[J]. 中华泌尿外科杂志, 2018, 39 (6): 433- 436.
23 Barbagli G , Vallasciani S , Romano G , et al. Morbidity of oral mucosa graft harvesting from a single cheek[J]. Eur Urol, 2010, 58 (1): 33- 41.
doi: 10.1016/j.eururo.2010.01.012
24 Wang A , Chua M , Talla V , et al. Lingual versus buccal mucosal graft for augmentation urethroplasty: A meta-analysis of surgical outcomes and patient-reported donor site morbidity[J]. Int Urol Nephrol, 2021, 53 (5): 907- 918.
doi: 10.1007/s11255-020-02720-7
25 Maarouf AM , Elsayed ER , Ragab A , et al. Buccal versus lingual mucosal graft urethroplasty for complex hypospadias repair[J]. J Pediatr Urol, 2013, 9 (6 Pt A): 754- 758.
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