北京大学学报(医学版) ›› 2014, Vol. 46 ›› Issue (6): 854-858.

• 论著 • 上一篇    下一篇

冠心病患者体成分与运动能力的相关性

白瑾,赵威,徐昕晔,刘萍,王鸿艳,吴晓月,李刘宁,高炜△   

  1. (北京大学第三医院心内科,卫生部心血管分子生物学与调节肽重点实验室,分子心血管学教育部重点实验室,北京100191)
  • 出版日期:2014-12-18 发布日期:2014-12-18

Correlation between body composition and exercise capacity in patients with coronary heart disease

BAI Jin, ZHAO Wei, XU Xin-ye, LIU Ping, WANG Hong-yan, WU Xiao-yue, LI Liu-ning, GAO Wei△   

  1. (Department of Cardiology, Peking University Third Hospital; Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing 100191, China)
  • Online:2014-12-18 Published:2014-12-18

摘要: 目的:应用人体成分分析仪测定冠心病患者的体成分,分析患者体成分与运动能力的关系,为更准确地评估患者身体成分,预测患者的运动能力及指导其后期康复运动提供依据。方法:入选2013年12月至2014年8月期间,就诊于北京大学第三医院心内科接受经皮腔内冠状动脉介入治疗(percutaneous coronary intervention,PCI)且心功能Ⅰ~Ⅱ级(NYHA分级)的冠心病患者663例,术后15~20 d内完成运动心肺功能评定(应用BRUCE平板运动方案,进行症状限制性平板运动试验)。在运动前应用Inboby720人体成分分析仪对患者进行体成分测定。结果: 663例冠心病患者均完成体成分测定及运动心肺功能评定。依据体重指数(body mass index,BMI)、体脂百分比(percentage of body fat,PBF)、腰臀比(waist-hip ratio,WHR)这3个指标诊断肥胖,其检出率分别为22.8%、63.3%和72.7%,仅有PBF与患者的运动能力呈负相关性(r=-0.306,P<0.001)。依据PBF分组,肥胖组较非肥胖组患者的运动能力下降,差异具有统计学意义(P<0.01)。依据运动心肺功能评定代谢当量(metabolic equivalent of energy,METs)将患者分为低、中、高运动功能储备组,只有PBF在3组患者中差异具有统计学意义(P<0.05)。结论:应用人体成分分析仪测定的PBF诊断肥胖更为准确,且与患者的运动能力呈负相关,是冠心病患者运动能力预测与指导康复运动的重要指标。

关键词: 冠心病, 体成分, 运动能力, 电阻抗

Abstract: Objective:To provide the evidence for more accurately assessing the patient’s body composition, predicting exercise capacity and guiding rehabilitation exercise by analyzing the body compositions in patients with coronary heart disease, and to study the correlation between body compositions and exercise capacity. Methods: The study enrolled 663 patients with coronary heart disease in NYHA Ⅰ-Ⅱ stages, who underwent coronary intervention therapy between December 2013 and August 2014. Between 15th and 20th days of the onset, cardiopulmonary exercising testing (CPET, Bruce Protocol) was conducted, and the body composition was measured with the Inboby720 body composition analyzer before CPET. Results: All the patients completed the body composition evaluation and the CPET. According to the three indicators of body mass index (BMI), percentage of body fat (PBF), waisthip ratio (WHR), the diagnostic rate of obesity was 22.8%, 63.3%, and 72.7%, respectively. There was a good negative correlation between PBF and exercise capacity (r=-0.306, P<0.001). Compared with non-obesity patients, the exercise capacity of obesity group decreased according to PBF (P<0.01). The patients were divided into low, moderate and high exercise capacity groups according to METs, and the difference was only the PBF among the three groups (P<0.05). Conclusion: PBF, measured by body composition, is a more accurate diagnosis of obesity and has a good negative correlation with exercise capacity, which can be used as an important indicator to predict the exercise capacity in patients with coronary heart disease and guide the rehabilitation exercise.

Key words: Coronary disease, Body composition, Exercise capacity, Electric impedance

[1] 杨航,杨林承,张瑞涛,凌云鹏,葛庆岗. 合并高血压、冠心病、糖尿病的新型冠状病毒肺炎患者发生病死的危险因素分析[J]. 北京大学学报(医学版), 2020, 52(3): 420-424.
[2] 刘欢,王宏宇,刘金波,赵红薇,周迎燕,李丽红. 颈动脉斑块患者大动脉功能与冠心病和下肢动脉疾病的关系[J]. 北京大学学报(医学版), 2017, 49(6): 1027-1033.
[3] 余灿清,陈怡平,吕筠,郭彧,Paul Sherliker,卞铮,周汇燕,谭云龙,陈君石,陈铮鸣,李立明. 中国30~79岁成人抑郁障碍与冠心病和脑卒中的关联[J]. 北京大学学报(医学版), 2016, 48(3): 465-471.
[4] 刘滕飞,张婧薇,陈夏欢,冯雪茹,柏中胜,刘梅林. 尿11-脱氢血栓素B2水平与2型糖尿病合并冠心病患者阿司匹林临床疗效的相关性研究[J]. 北京大学学报(医学版), 2015, 47(6): 920-924.
[5] 张永珍, 高炜. 稳定性冠心病诊治策略的选择:欧美指南给我们的提示[J]. 北京大学学报(医学版), 2014, 46(6): 832-835.
[6] 夏经钢, 曲杨, 胡少东, 许骥, 尹春琳, 徐东. 强化调脂对行非心脏手术的冠状动脉粥样硬化性心脏病患者的心肌保护作用及机制初探[J]. 北京大学学报(医学版), 2014, 46(4): 601-605.
[7] 李蓬*, 和璐, 沙月琴, 栾庆先 . 陈旧性心肌梗死患者的牙周状况[J]. 北京大学学报(医学版), 2013, 45(1): 22-26.
[8] 李春, 王秀茹*, 唐熠达, 安媛, 周云杉, 郭时伟, 张晓盈, 段天骄, 朱佳鑫, 李晓峰, 王莉枝, 王彩虹, 王永福, 杨荣, 王国春, 卢昕, 朱平. 全国多中心类风湿关节炎冠心病危险因素的现况调查[J]. 北京大学学报(医学版), 2012, 44(2): 176-181.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!