Email Alert | RSS

北京大学学报（医学版） ›› 2020, Vol. 52 ›› Issue (5): 980-984. doi: 10.19723/j.issn.1671-167X.2020.05.032

• 短篇论著 • 上一篇    下一篇

156例特应性皮炎患者血清吸入和食物过敏原特异性免疫球蛋白E及患者自觉过敏情况

胡宇晴,张建中   

  1. 北京大学人民医院皮肤科,北京 100044
  • 收稿日期:2018-12-28 出版日期:2020-10-18 发布日期:2020-10-15
  • 通讯作者: 张建中

  • Received:2018-12-28 Online:2020-10-18 Published:2020-10-15

RICH HTML

 6   

PDF (PC)

163

关键词: 特应性皮炎, 过敏原, 免疫球蛋白E

中图分类号: 

  • R781.67

表1

156例特应性皮炎患者吸入和食物过敏原血清sIgE检测结果"

Allergen Positive sIgE detection, n(%)
Aeroallergen 61 (39.1)
Dust mites 40 (25.6)
Artemisia 16 (10.3)
Mixture of epithelia 15 (9.6)
Mixed molds 17 (10.9)
Mixed botany 3 (1.9)
Mixed pollens 10 (6.4)
Willow 9 (5.8)
Poplar 6 (3.9)
Food allergen 31 (19.9)
Egg 10 (6.4)
Milk 15 (9.6)
Shrimp 10 (6.4)
Beef 9 (5.8)
Mutton 11 (7.1)
Fish 6 (3.9)
Crab 13 (8.3)
Staple foods 3 (1.9)

图1

不同年龄组特应性皮炎患者吸入和食物过敏原血清sIgE检测结果比较"

表2

患者自觉过敏情况与血清过敏原sIgE检测结果的比较"

Allergen Subjective causative factors of
allergen, n(%)		 Positive results of serum sIgE
detection, n(%)
Aeroallergen
Dust (dust mites) 42 (26.9) 40 (25.6)
Armoise (artemisia) 17 (10.9) 16 (10.3)
Mixture of epithelia (cat fur or dog fur) 26 (16.7) 15 (9.6)
Cold air 31 (19.9)
Moist environment (mixed molds) 54 (34.6) 17 (10.9)
Botany (including mixed botany, pollens, willow and poplar) 15 (9.6) 28 (18.0)
Furniture 15 (9.6)
Traveling 16 (10.3)
Food allergen
Egg 8 (5.1) 10 (6.4)
Milk 7 (4.5) 15 (9.6)
Shrimp 46 (29.5) 10 (6.4)
Mutton 24 (15.4) 11 (7.1)
Beef 19 (12.2) 9 (5.8)
Fish 35 (22.4) 6 (3.9)
Crab 42 (26.9) 13 (8.3)
Staple foods 2 (1.3) 3 (1.9)
Peanuts 7 (4.5)
Nuts 6 (3.9)
Spicy food 42 (26.9)

表3

过敏原检测结果与患者自觉过敏症状符合情况比较"

Allergen Serum test accorded with
subjective symptoms, n(%)		 Serum test disaccorded with
subjective symptoms, n(%)
Serum test(+)/
Subjective
symptoms(+)		 Serum test(-)/
Subjective
symptoms(-)		 Serum test(+)/
Subjective
symptoms(-)		 Serum test(-)/
Subjective
symptoms(+)
Aeroallergen
Dust mites (dust) 18 (11.5) 92 (59.0) 22 (14.1) 24 (15.4)
Artemisia (armoise) 5 (3.2) 128 (82.0) 11 (7.0) 12 (7.7)
Mixture of epithelia (cat fur or dog fur) 8 (5.1) 123 (78.8) 7 (4.5) 18 (11.5)
Mixed molds (moist environment) 10 (6.4) 93 (59.6) 7 (4.5) 45 (28.8)
Mixed botany, pollens, willow or poplar (botany) 3 (1.9) 117 (75.0) 25 (16.0) 12 (7.7)
Food allergen
Egg 3 (1.9) 141 (90.3) 7 (4.5) 5 (3.2)
Milk 4 (2.6) 138 (88.5) 11 (7.0) 3 (1.9)
Shrimp 7 (4.5) 107 (68.6) 3 (1.9) 39 (25.0)
Beef 4 (2.6) 127 (81.4) 5 (3.2) 20 (12.8)
Mutton 4 (2.6) 130 (83.3) 7 (4.5) 15 (9.6)
Fish 3 (1.9) 118 (75.6) 3 (1.9) 32 (20.5)
Crab 10 (6.4) 111 (71.2) 3 (1.9) 32 (20.5)
Staple foods 1 (0.6) 152 (97.4) 2 (1.3) 1 (0.6)

图2

特应性皮炎患者EASI指数和血清过敏原阳性数目的相关性(P=0.272, R=0.088) "

[1] Akdis CA, Akdis M, Bieber T, et al. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report[J]. J Allergy Clin Immunol, 2006,118(1):152-169.
doi: 10.1016/j.jaci.2006.03.045 pmid: 16815151
[2] Wollenberg A, Oranje A, Deleuran M, et al. ETFAD/EADV Eczema task force 2015 position paper on diagnosis and treatment of atopic dermatitis in adult and paediatric patients[J]. J Eur Acad Dermatol Venereol, 2016,30(5):729-747.
pmid: 27004560
[3] Liu P, Zhao Y, Mu ZL, et al. Clinical features of adult/adolescent atopic dermatitis and Chinese criteria for atopic dermatitis[J]. Chin Med J (Engl), 2016,129(7):757-762.
[4] Hanifin JM. Diagnostic criteria for atopic dermatitis: Consider the context[J]. Arch Dermatol, 1999,135(12):1551.
pmid: 10606074
[5] Darsow U, Vieluf D, Ring J. Evaluating the relevance of aero-allergen sensitization in atopic eczema with the atopy patch test: A randomized, double-blind multicenter study. Atopy Patch Test Study Group[J]. J Am Acad Dermatol, 1999,40(1):187-193.
doi: 10.1016/S0190-9622(99)70186-6
[6] Chu H, Shin JU, Park CO, et al. Clinical diversity of atopic dermatitis: A review of 5 000 patients at a single institute[J]. Allergy Asthma Immunol Res, 2017,9(2):158-168.
doi: 10.4168/aair.2017.9.2.158 pmid: 28102061
[7] Scalabrin DM, Bavbek S, Perzanowski MS, et al. Use of specific IgE in assessing the relevance of fungal and dust mite allergens to atopic dermatitis: A comparison with asthmatic and nonasthmatic control subjects[J]. J Allergy Clin Immunol, 1999,104(6):1273-1279.
doi: 10.1016/s0091-6749(99)70024-2 pmid: 10589012
[8] Celakovská J, Bukac J. Analysis of food allergy in atopic dermatitis patients: Association with concomitant allergic diseases [J]. Indian J Dermatol, 2014,59(5):445-450.
doi: 10.4103/0019-5154.139867 pmid: 25284847
[9] Sampson HA. The evaluation and management of food allergy in atopic dermatitis[J]. Clin Dermatol, 2003,21(3):183-192.
doi: 10.1016/s0738-081x(02)00363-2 pmid: 12781436
[10] Mastrorilli C, Caffarelli C, Hoffmann-Sommergruber K. Food allergy and atopic dermatitis: Prediction, progression and prevention[J]. Pediatr Allergy Immunol, 2017,28(8):831-840.
pmid: 29117431
[1] 马晓蕾, 孙青苗, 贾军, 蔡林. 过敏性皮肤病患者血清食入性和吸入性过敏原特异性IgE结果分析[J]. 北京大学学报（医学版）, 2012, 44(5): 765-769.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] 张三. 中文标题测试[J]. 北京大学学报（医学版）, 2010, 42(1): 1 -10 .
[2] 赵磊, 王天龙 . 右心室舒张末期容量监测用于肝移植术中容量管理的临床研究[J]. 北京大学学报（医学版）, 2009, 41(2): 188 -191 .
[3] 万有, , 韩济生, John E. Pintar. 孤啡肽基因敲除小鼠电针镇痛作用增强[J]. 北京大学学报（医学版）, 2009, 41(3): 376 -379 .
[4] 张燕, 韩志慧, 钟延丰, 王盛兰, 李玲玲, 郑丹枫. 骨骼肌活组织检查病理诊断技术的改进及应用[J]. 北京大学学报（医学版）, 2009, 41(4): 459 -462 .
[5] 林红, 王玉凤, 吴野平. 学校生活技能教育对小学三年级学生行为问题影响的对照研究[J]. 北京大学学报（医学版）, 2007, 39(3): 319 -322 .
[6] 丰雷, 程嘉, 王玉凤. 注意缺陷多动障碍儿童的运动协调功能[J]. 北京大学学报（医学版）, 2007, 39(3): 333 -336 .
[7] 李岳玲, 钱秋瑾, 王玉凤. 儿童注意缺陷多动障碍成人期预后及其预测因素[J]. 北京大学学报（医学版）, 2007, 39(3): 337 -340 .
[8] . 书讯[J]. 北京大学学报（医学版）, 2007, 39(3): 225 -328 .
[9] 牟向东, 王广发, 刁小莉, 阙呈立. 肺黏膜相关淋巴组织型边缘区B细胞淋巴瘤一例[J]. 北京大学学报（医学版）, 2007, 39(4): 346 -350 .
[10] 张宏文, 丁洁, 王芳, 杨惠霞. 一例X连锁Alport综合征女性妊娠期随访[J]. 北京大学学报（医学版）, 2007, 39(4): 351 -354 .
ISSN 1671-167X
CN 11-4691/R
主管单位：中华人民共和国教育部
主办单位：北京大学
地址： 北京市海淀区学院路38号 北京大学医学部 《北京大学学报（医学版）》
邮编：100191
电话：010-82801551
Email： xbbjb2@bjmu.edu.cn

《北京大学学报（医学版）》
微信公众号
版权所有 © 2018 《北京大学学报（医学版）》编辑部