北京大学学报(医学版) ›› 2025, Vol. 57 ›› Issue (2): 396-399. doi: 10.19723/j.issn.1671-167X.2025.02.028

• 病例报告 • 上一篇    下一篇

自体肾移植术治疗患儿复杂肾动脉瘤1例

余磊1, 杨文博1, 杨宇帆2, 王强1,△()   

  1. 1. 北京大学人民医院泌尿外科,北京大学应用碎石技术研究所,北京 100044
    2. 北京大学护理学院,北京 100191
  • 收稿日期:2024-09-04 出版日期:2025-04-18 发布日期:2025-04-12
  • 通讯作者: 王强 E-mail:wq301135@163.com

Renal autotransplantation for the treatment of complex renal aneurysm in a child: A case report

Lei YU1, Wenbo YANG1, Yufan YANG2, Qiang WANG1,△()   

  1. 1. Department of Urology, Peking University People's Hospital, Institute of Applied Lithotripsy Technology, Peking University, Beijing 100044, China
    2. School of Nursing, Peking University, Beijing 100191, China
  • Received:2024-09-04 Online:2025-04-18 Published:2025-04-12
  • Contact: Qiang WANG E-mail:wq301135@163.com

RICH HTML

  

关键词: 自体肾移植, 肾动脉, 腹主动脉瘤, 复杂肾动脉瘤, 离体手术

Abstract:

Renal autotransplantation (RA) offers significant technical advantages for the management of certain complex renal vascular diseases, such as complex renal aneurysms and renal artery malformations. This report describes a case of a 5-year-old child with a complex left renal artery aneurysm combined with multiple aneurysms. The child was admitted to Peking University People's Hospital in December 2023 due to a one-year history of intermittent abdominal pain, with an abdominal mass detected in the past month. Computed tomography angiography(CTA) revealed multiple vascular anomalies, including: (1) a left renal artery aneurysm, (2) an abdominal aortic aneurysm, and (3) a right iliac artery aneurysm. After a comprehensive evaluation of these findings, the surgical team developed a treatment plan that involved the excision of the left renal artery aneurysm, autotransplantation of the left kidney, and resection of the abdominal aortic aneurysm with an artificial vascular catheterization. During surgery, it was discovered that the left renal artery anatomy was highly complex. The artery had two primary branches, along with an additional polar artery located at the lower pole. The aneurysm was identified at the distal end of the renal artery trunk, with a pronounced bulging at the intersection between the main renal artery trunk and its secondary branches. Due to these structural complexities, the team decided to use an ex vivo surgical approach to repair the aneurysm. Ex vivo repair involves temporarily removing the kidney from the body to repair the renal artery aneurysm with enhanced precision, enabling the surgical team to meticulously reconstruct the complex vascular architecture without the constraints of in vivo manipulation. The ex vivo repair of the renal artery aneurysm was successful, allowing for accurate vascular reconstruction and avoiding potential intraoperative complications. Following the reconstruction, the kidney was autotransplanted back into the child's body, and blood flow was effectively restored to the organ. The therapeutic outcome was excellent, with the child experiencing no postoperative complications. The patient recovered well and was discharged from the hospital in stable condition. This case underscores the value of renal autotransplantation combined with ex vivo repair for pediatric patients with complicated renal artery aneurysms. Through this report, we aim to provide insights and considerations for the surgical treatment of similar cases in children with complex renal vascular anatomy.

Key words: Transplantation, autologous, Renal artery, Aortic aneurysm, Abdominal, Complex renal aneurysm, Ex vivo surgery

中图分类号: 

  • R726.9

图1

术前CTA所见"

图2

术中所见:腹主动脉瘤和左肾上极肾动脉瘤形成"

图3

工作台肾解剖结构及其示意图"

图4

动脉重建、自体肾移植术手术过程及其示意图"

1 Veiga C , Machado R , Nunes-Carneiro D , et al. Ex vivo repair and renal auto-transplantation for treatment of a renal artery aneurysm after endovascular failure[J]. BMJ Case Rep, 2019, 12 (12): e231380.
doi: 10.1136/bcr-2019-231380
2 张健, 林俊, 沈洪亮, 等. 自体大隐静脉逆转替代肾动脉或肾静脉自体肾移植二例[J]. 中华移植杂志(电子版), 2021, 15 (2): 101- 104.
3 Duprey A , Chavent B , Meyer-Bisch V , et al. Editor's choice: Ex vivo renal artery repair with kidney autotransplantation for renal artery branch aneurysms: Long-term results of sixty-seven procedures[J]. Eur J Vasc Endovasc Surg, 2016, 51 (6): 872- 879.
doi: 10.1016/j.ejvs.2016.02.017
4 Buck DB , Curran T , McCallum JC , et al. Management and outcomes of isolated renal artery aneurysms in the endovascular era[J]. J Vasc Surg, 2016, 63 (1): 77- 81.
doi: 10.1016/j.jvs.2015.07.094
5 Coleman DM , Stanley JC . Renal artery aneurysms[J]. J Vasc Surg, 2015, 62 (3): 779- 785.
doi: 10.1016/j.jvs.2015.05.034
6 Ye P , Wu H , Chen Y , et al. Endovascular therapy for distal hilar renal artery aneurysm: A case report and literature review[J]. J Int Med Res, 2022, 50 (1): 3000605211069282.
doi: 10.1177/03000605211069282
7 González J , Esteban M , Andrés G , et al. Renal artery aneurysms[J]. Curr Urol Rep, 2014, 15 (1): 376.
doi: 10.1007/s11934-013-0376-z
8 Schulte W , Rodriguez-Davalos M , Lujic M , et al. Operative management of hilar renal artery aneurysm in a aregnant aatient[J]. Ann Vasc Dis, 2015, 8 (3): 242- 245.
doi: 10.3400/avd.cr.15-00026
9 Adrahtas D , Jasinski P , Koullias G , et al. Endovascular treatment of a complex renal artery aneurysm using coils and the pipeline embolization device in a patient with a solitary kidney[J]. Ann Vasc Surg, 2016, 36, 291.e5- 291.e9.
doi: 10.1016/j.avsg.2016.03.004
10 Jain P , Naik AL , Ansari A , et al. Ex-vivo repair for multiple and intraparenchymal renal artery aneurysms[J]. J Vasc Bras, 2021, 20, e20210012.
doi: 10.1590/1677-5449.210012
11 Silski LS , Henry ML , Rajab A , et al. Case report: treatment of renal artery aneurysms by ex vivo renal artery aneurysm repair and transplantation[J]. Transplant Proc, 2017, 49 (10): 2374- 2377.
doi: 10.1016/j.transproceed.2017.07.010
12 Chen X , Zhao J , Huang B , et al. In situ revascularization of bilateral complicated giant renal artery aneurysms: Case report[J]. Medicine (Baltimore), 2019, 98 (6): e14329.
doi: 10.1097/MD.0000000000014329
13 Sousa J , Mansilha A . Endovascular treatment of symptomatic renal artery aneurysm with hostile anatomy[J]. Eur J Vasc Endovasc Surg, 2017, 53 (6): 843.
doi: 10.1016/j.ejvs.2017.02.018
14 Orion KC , Abularrage CJ . Renal artery aneurysms: Movement toward endovascular repair[J]. Semin Vasc Surg, 2013, 26 (4): 226- 232.
doi: 10.1053/j.semvascsurg.2014.06.007
15 Hislop SJ , Patel SA , Abt PL , et al. Therapy of renal artery aneurysms in New York State: Outcomes of patients undergoing open and endovascular repair[J]. Ann Vasc Surg, 2009, 23 (2): 194- 200.
doi: 10.1016/j.avsg.2008.10.002
16 Tsilimparis N , Reeves JG , Dayama A , et al. Endovascular vs. open repair of renal artery aneurysms: Outcomes of repair and long-term renal function[J]. J Am Coll Surg, 2013, 217 (2): 263- 269.
doi: 10.1016/j.jamcollsurg.2013.03.021
17 Chandra A , O'Connell JB , Quinones-Baldrich WJ , et al. Aneurysmectomy with arterial reconstruction of renal artery aneurysms in the endovascular era: A safe, effective treatment for both aneurysm and associated hypertension[J]. Ann Vasc Surg, 2010, 24 (4): 503- 510.
doi: 10.1016/j.avsg.2009.07.030
[1] 赵世录, 栾景源, 冯琦琛, 刘启佳, 杨广鑫, 贾子昌, 庄金满. 球囊阻断联合瘤腔内凝血酶注射治疗破裂腹主动脉瘤[J]. 北京大学学报(医学版), 2024, 56(6): 1052-1057.
[2] 李伟浩,李伟,张学民,李清乐,焦洋,张韬,蒋京军,张小明. 去分支杂交手术和传统手术治疗胸腹主动脉瘤的结果比较[J]. 北京大学学报(医学版), 2022, 54(1): 177-181.
[3] 马伟国,秦彩朋,于路平,张晓鹏,刘士军,王永顺, 白文俊,徐涛. 后腹腔镜下孤立肾采用肾动脉非阻断法行保留肾单位肾肿瘤剜除术的疗效评价[J]. 北京大学学报(医学版), 2018, 50(4): 759-761.
[4] 于路平,赵卫红,刘士军,李清,徐涛. 先天性肾动静脉瘘伴肾动脉多支畸形病例分析[J]. 北京大学学报(医学版), 2018, 50(4): 722-728.
[5] 冯琦琛,李选,栾景源,王昌明,李天润. 肾滤过分数评价肾动脉支架植入术对动脉硬化性肾动脉狭窄的治疗效果[J]. 北京大学学报(医学版), 2017, 49(1): 158-163.
[6] 王伟民. 肾交感神经消融治疗难治性高血压[J]. 北京大学学报(医学版), 2014, 46(6): 836-837.
[7] 张春丽, 李乾, 左力, 崔盈, 王彦福, 郭凤琴, 赵光宇, 张旭初, 周玉红, 王荣福. 肾动态显像法与双血浆法测定肾小球滤过率的对比分析[J]. 北京大学学报(医学版), 2004, 36(6): 612-615.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!