北京大学学报(医学版) ›› 2017, Vol. 49 ›› Issue (6): 996-1002. doi: 10.3969/j.issn.1671-167X.2017.06.011

• 论著 • 上一篇    下一篇

分支血管灌注不良分型在主动脉夹层腔内修复术中的应用及分析

韩晓峰,郭曦,李铁铮,刘光锐,黄连军△   

  1. (首都医科大学附属北京安贞医院介入诊疗科,北京市心肺血管疾病研究所, 北京100029)
  • 出版日期:2017-12-18 发布日期:2017-12-18
  • 通讯作者: 黄连军 E-mail: huanglianjun2008@163.com

Application and analysis of abdominal aortic branch malperfusion pattern in thoracic endovascular aortic repair for Stanford B aortic dissection

HAN Xiao-feng, GUO Xi, LI Tie-zheng, LIU Guang-rui, HUANG Lian-jun△   

  1. (Department of Diagnostic and Interventional Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vascular Diseases, Beijing 100029, China)
  • Online:2017-12-18 Published:2017-12-18
  • Contact: HUANG Lian-jun E-mail: huanglianjun2008@163.com

摘要: 目的:分析Stanford B型主动脉夹层累及腹腔四分支血管灌注不良情况,探讨腔内修复术对腹腔四分支血管灌注的影响。方法:回顾性分析2015年9月至2016年3月收治并确诊为Stanford B型主动脉夹层的患者32例,男28例,平均年龄(52.9±9.6) 岁(32~70岁),收集患者的临床影像学资料及随访结果。基于Nagamine分支血管灌注不良细化分型,分析术前和术后主动脉CT血管造影(computed tomography angiography,CTA)影像资料,对灌注不良的腹腔四分支血管(腹腔干动脉、肠系膜上动脉、左肾动脉及右肾动脉)进行分类和统计学分析。结果:32例患者腹腔四分支血管共128支,其中86支分支血管(67.2%)属于Ⅰ类灌注不良,Ⅰ-a亚型占60.9%(78/128),Ⅰ-b亚型占0.8%(1/128),Ⅰ-c亚型占5.5%(7/128);14支分支血管(10.9%)属于Ⅱ类灌注不良,Ⅱ-a亚型占3.9%(5/128),Ⅱ-b-1亚型占3.9%(5/128),Ⅱ-b-2亚型占3.1%(4/128);16支分支血管(12.5%)属于Ⅲ类灌注不良,均为Ⅲ-a亚型(无Ⅲ-b和Ⅲ-c亚型);其余12支分支血管未受累。32例患者均完成了胸主动脉腔内修复术(thoracic endovascular aortic repair, TEVAR),手术成功率100%,术后平均随访4个月。术后复查CTA显示,14支(10.9%)属于“高危”灌注不良亚型(Ⅰ-b、Ⅰ-c和Ⅱ-b-2亚型)的分支血管中,13支(92.9%)灌注不良明显改善,其余1支的灌注亚型由Ⅰ-b转归为Ⅰ-c。结论:Stanford B型主动脉夹层累及腹腔四分支血管灌注明显受损所占的比例较低,TEVAR能有效改善分支血管的灌注不良状态,推广Nagamine分支血管灌注不良细化分型,对判断夹层受累分支血管灌注不良状况及指导是否分支血管腔内重建意义重大。

关键词: 主动脉夹层, 腔内治疗, 胸主动脉腔内修复术, 局部血流

Abstract: Objective: To evaluate the efficiency of thoracic endovascular aortic repair (TEVAR) in dealing with abdominal aortic branch malperfusion based on the analysis of aortic computed tomography angiography (CTA) images in pre-and postTEVAR. Methods: Retrospective analysis from September 2015 to March 2016 in single institution to 32 patients, diagnosed as Stanford B aortic dissection with abdominal aortic branch malperfusion, CTA images in pre- and postTEVAR were collected. Based on the aortic branch malperfusion pattern redefined by Nagamine, we identified and characterized branch malperfusion pattern for four abdominal aortic branches (celiac trunk, superior mesenteric artery, bilate-ral renal artery) in statistical analysis. Results: In the four abdominal aortic branches (total 128 branches), 86 branches (67.2%) expressed with Class Ⅰ patterns, in which subtype Ⅰ-b presented with 0.8%, subtype Ⅰ-c with 5.5%; 14 branches (10.9%) expressed with Class Ⅱ patterns, in which subtype Ⅱ-b-1 with 3.9%, subtype Ⅱ-b-2 with 3.1%; 16 branches (12.5%) expressed with Class Ⅲ patterns, all with subtype Ⅲ-a, no subtype Ⅲ-b and Ⅲ-c presented. The remaining 12 branches were normal. The 100% successful rate of TEVAR obtained in 32 patients performed. The mean followingup was 4 months. Aortic CTA showed that among the 14 “high-risk” abdominal aortic branch malperfusion, 13 (92.9%) with obvious branch malperfusion in post-TEVAR were observed to improve, and the remaining one branch malperfusion (7.1%) was observed to change from subtype Ⅰ-b to Ⅰ-c. Conclusion: Few ratios in abdominal aortic branches suffered with obvious malperfusion complicated by Stanford B aortic dissection. For branches with “highrisk” malperfusion pattern, optimal changes were observed in abdominal aortic branch without revascularization in postTEVAR, as well other branches with non-“highrisk” pattern perfusion were mostly stable in post-TEVAR. It could be of profound benefit to extend branch malperfusion patterns redefined by Nagamine in clinical practice to assess aortic dissection and in further guide for revascularization or not.

Key words: Aortic dissection, Endovascular procedures, Thoracic endovascular aortic repair, Regional blood flow

中图分类号: 

  • R654
[1] 庄金满,李选,李天润,赵军,栾景源,王昌明. 股浅动脉重建对下肢动脉硬化闭塞症治疗的随机病例对照研究[J]. 北京大学学报(医学版), 2017, 49(1): 153-157.
[2] 李晓惠, 杜军保, 丁亚光, 金红芳, 卜定方, 汤秀英, 唐朝枢. 硫化氢供体对实验性高肺血流性肺动脉高压及内源性一氧化碳/血红素氧合酶体系的影响[J]. 北京大学学报(医学版), 2006, 38(2): 135-139.
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