北京大学学报(医学版) ›› 2017, Vol. 49 ›› Issue (6): 1008-1013. doi: 10.3969/j.issn.1671-167X.2017.06.013

• 论著 • 上一篇    下一篇

不同麻醉方法对髋部骨折老年患者术后转归的影响

魏滨1,张华2,徐懋1,李民1,王军1,张利萍1,郭向阳1,赵一鸣2,周方3△   

  1. (北京大学第三医院 1. 麻醉科, 2. 临床流行病学研究中心, 3. 骨科, 北京100191)
  • 出版日期:2017-12-18 发布日期:2017-12-18
  • 通讯作者: 周方 E-mail:zhou.md@126.com

Effect of different anesthetic methods on postoperative outcomes in elderly patients undergoing hip fracture surgery

WEI Bin1, ZHANG Hua2, XU Mao1, LI Min1, WANG Jun1, ZHANG Li-ping1, GUO Xiang-yang1, ZHAO Yi-ming2, ZHOU Fang3△   

  1. (1. Department of Anesthesiology, 2. Center for Clinical Epidemiological Research, 3. Department of Orthopaedic Sur-gery, Peking University Third Hospital, Beijing 100191, China)
  • Online:2017-12-18 Published:2017-12-18
  • Contact: ZHOU Fang E-mail:zhou.md@126.com

摘要: 目的:比较全身麻醉(general anesthesia, GA)和区域阻滞麻醉(regional anesthesia, RA)对接受手术治疗的髋部骨折老年患者术后心肺并发症和住院期间死亡率的影响。方法:回顾性分析我院骨科2005年1月至2014年12月间收治的572例髋部骨折老年患者的临床资料,分别记录患者性别、年龄、术前内科合并症、术前卧床时间、骨折原因、手术和麻醉方法、术后心肺并发症以及住院期间的死亡率。应用多重Logistic回归模型分析不同麻醉方法对髋部骨折老年患者术后住院死亡率的影响。结果:8例老年患者发生住院期间死亡(8/572,死亡率1.4%),其中RA组5例(5/392,死亡率1.3%),GA组3例(3/180,死亡率1.7%),两组患者间住院死亡率的差异无统计学意义(P>0.05),多重Logistic回归分析显示,性别(OR=0.18,95% CI:0.03~1.05,P=0.057)、年龄(OR=1.22,95% CI:1.07~1.38,P=0.002)、术前肺部合并症(OR=12.09,95% CI:2.28~64.12,P=0.003)和手术方式(OR=9.36,95% CI:1.34~64.26,P=0.024)是术后发生住院期间死亡的独立危险因素。36例患者术后发生心血管系统并发症(36/572,发生率6.3%),其中RA组19例(19/392,发生率4.8%),GA组17例(17/180,发生率9.4%), 多重Logistic回归分析显示,年龄(OR=1.13,95% CI:1.07~1.19,P<0.001)、高血压(OR=2.72,95% CI:1.24~5.96,P=0.012)和术前脑血管合并症(OR=2.11,95% CI:0.99~4.52,P=0.054)是发生术后心血管系统并发症的独立危险因素。56例患者术后发生呼吸系统并发症(56/572,发生率9.8%),其中RA组19例(19/392,发生率4.8%),GA组37例(37/180,发生率20.6%),多重Logistic回归分析显示,年龄(OR=1.13,95% CI:1.07~1.19,P<0.001)、术前肺部合并症(OR=2.89,95% CI:1.28~7.05,P=0.020)、术前卧床时间(OR=1.11,95% CI:1.04~1.18,P=0.003)和麻醉方法(OR=5.86,95% CI:2.98~11.53,P<0.001)是术后发生呼吸系统并发症的独立危险因素。结论:RA和GA对接受手术治疗的髋部骨折老年患者住院期间死亡率无显著影响,但RA组患者术后呼吸系统并发症的发生率低于GA组患者。

关键词: 髋骨折, 麻醉, 老年人

Abstract: Objective: To investigate the effect of general or regional anesthesia on postoperative cardiopulmonary complications and inpatient mortality after hip fracture surgery in elderly patients. Me-thods: A retrospective analysis was conducted according to the medical records of 572 elderly patients with hip fractures admitted to our hospital from January 1, 2005 to December 31, 2014. The age, gender, preoperative comorbidities, length of preoperative bedridden time, mechanism of injury, surgical types, anesthetic methods, major postoperative complications and inpatient mortality were recorded. Multivariate Logistic regression analysis was applied to analyze the impact of different anesthetic methods on inpatient mortality in these patients. Results: Of the 572 patients, 392 (68.5%) received regional anesthesia. Inpatient death occurred in 8 (8/572, mortality: 1.4%), including 5 cases of RA group (5/392, mortality: 1.3%) and 3 cases of GA group (3/180, mortality: 1.7%). There was no statistically significant difference between the two groups in inpatient mortality (P>0.05). Multiple Logistic regression analysis showed that gender (odds ratio: 0.18, 95% CI: 0.03-1.05, P=0.057), age (odds ratio: 1.22, 95% CI: 1.07-1.38, P=0.002), preoperative pulmonary comorbidities (odds ratio: 12.09, 95% CI: 2.28-64.12, P=0.003) and surgical types (odds ratio: 9.36, 95% CI: 1.34-64.26, P=0.024) were risk factors for inpatient mortality. Postoperative cardiovascular complications occurred in 36 patients (36/572, morbidity: 6.3%), with 19 patients in RA group (19/392, morbidity: 4.8%),and 17 patients in GA group (17/180, morbidity: 9.4%). Multiple Logistic regression analysis showed that age (odds ratio: 1.13, 95% CI: 1.07-1.19, P<0.001), hypertension (odds ratio: 2.72, 95% CI: 1.24-5.96, P=0.012) and preoperative cerebral comorbidities (odds ratio: 2.11, 95% CI: 0.99-4.52, P=0.054) were risk factors for postoperative cardiovascular complications. Postoperative pulmonary complications occurred in 56 patients (56/572, morbidity: 9.8%), with 19 patients in RA group (19/392, morbidity: 4.8%), and 37 patients in GA group (37/180, morbidity: 20.6%). Multiple Logistic regression analysis showed that age (odds ratio: 1.13, 95% CI: 1.07-1.19, P<0.001), preoperative pulmonary comorbidities (odds ratio: 2.89, 95% CI: 1.28-7.05, P=0.020), length of preoperative bedridden time (odds ratio: 1.11, 95% CI: 1.04-1.18, P=0.003) and anesthetic methods (odds ratio: 5.86, 95% CI: 2.98-11.53, P<0.001) were risk factors for postoperative pulmonary complications. Conclusion: General anesthesia may not affect the inpatient mortality after hip fracture surgery in elderly patients. Regional anesthesia is associated with a lower risk of pulmonary complications after surgical procedure compared with general anesthesia.

Key words: Hip fractures, Anesthesia, Aged

中图分类号: 

  •  
[1] 刘园梅, 傅义程, 郝靖欣, 张福春, 刘慧琳. 老年髋部骨折患者住院期间发生术后心力衰竭的列线图预测模型的构建及验证[J]. 北京大学学报(医学版), 2024, 56(5): 874-883.
[2] 王军, 姚兰, 张宁, 索利斌, 李红培, 魏越, 查鹏, 梁正, 刘鲲鹏. 单侧胸椎旁阻滞对实施双腔气管插管患者血流动力学和意识水平的影响[J]. 北京大学学报(医学版), 2024, 56(5): 890-895.
[3] 张浩宇,石逸雯,潘薇,刘爱萍,孙昕霙,李曼,张旭熙. 基于不同失能水平的老年人照料需求的影响因素[J]. 北京大学学报(医学版), 2024, 56(3): 431-440.
[4] 靖婷,江华,李婷,申倩倩,叶兰,曾银丹,梁文欣,冯罡,司徒文佑,张玉梅. 中国西部5城市中老年人血清25羟基维生素D与握力的相关性[J]. 北京大学学报(医学版), 2024, 56(3): 448-455.
[5] 林郁婷,王华丽,田宇,巩俐彤,常春. 北京市老年人认知功能的影响因素[J]. 北京大学学报(医学版), 2024, 56(3): 456-461.
[6] 汤华萌,袁典琪,王明星,杨晗冰,郭超. 数字融入和健康生活方式对社会经济状况与老年人抑郁关系的序列中介作用[J]. 北京大学学报(医学版), 2024, 56(2): 230-238.
[7] 刘慧丽,吕彦函,王晓晓,李民. 老年患者腹腔镜泌尿系肿瘤根治术后慢性疼痛的影响因素[J]. 北京大学学报(医学版), 2023, 55(5): 851-856.
[8] 祝春素,连至炜,崔一民. 中国中老年人抑郁和慢性病的关联[J]. 北京大学学报(医学版), 2023, 55(4): 606-611.
[9] 史成梅,周阳,杨宁,李正迁,陶一帆,邓莹,郭向阳. 丙泊酚用于无痛胃肠镜检查对患者术后精神活动的影响[J]. 北京大学学报(医学版), 2023, 55(2): 324-327.
[10] 王洁初,姚优修,郭向阳. 严重低钾血症致麻醉后潜在致命性心律失常1例的术中管理[J]. 北京大学学报(医学版), 2023, 55(1): 186-189.
[11] 康志宇,王磊磊,韩永正,郭向阳. 北京冬季奥林匹克运动会运动员手术的麻醉管理[J]. 北京大学学报(医学版), 2022, 54(4): 770-773.
[12] 刘光奇,庞元捷,吴疆,吕敏,于孟轲,李雨橦,黄旸木. 2013—2019年流感季北京市住院老年人流感疫苗接种趋势分析[J]. 北京大学学报(医学版), 2022, 54(3): 505-510.
[13] 刘杰,郭超. 正/负性情绪对中国老年人死亡风险影响的前瞻性队列研究[J]. 北京大学学报(医学版), 2022, 54(2): 255-260.
[14] 李佳,徐钰,王优雅,高占成. 老年流感肺炎的临床特征及D-二聚体与疾病严重程度的相关性[J]. 北京大学学报(医学版), 2022, 54(1): 153-160.
[15] 穆东亮,薛铖,安彬,王东信. 硬膜外阻滞与结直肠癌患者术后远期生存状态的关系:一项倾向性评分匹配的回顾性研究[J]. 北京大学学报(医学版), 2021, 53(6): 1152-1158.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!