北京大学学报(医学版) ›› 2019, Vol. 51 ›› Issue (5): 813-818. doi: 10.19723/j.issn.1671-167X.2019.05.004

• 论著 • 上一篇    下一篇

基于移动终端开展中国新生儿出生特征研究

赵丽君,李宏田(),张亚黎,周玉博,刘建蒙()   

  1. 北京大学生育健康研究所,卫生部生育健康重点实验室,北京大学公共卫生学院流行病与卫生统计学系, 北京 100191
  • 收稿日期:2017-08-29 出版日期:2019-10-18 发布日期:2019-10-23
  • 通讯作者: 李宏田,刘建蒙 E-mail:liht@bjmu.edu.cn;liujm@pku.edu.cn
  • 基金资助:
    国家重点研发计划(2016YFC1000401);惠氏营养品资助课题

Mobile terminal-based survey on the birth characteristics for Chinese newborns

Li-jun ZHAO,Hong-tian LI(),Ya-li ZHANG,Yu-bo ZHOU,Jian-meng LIU()   

  1. Institute of Reproductive and Child Health, Ministry of Health Key Laboratory of Reproductive Health, Department of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China
  • Received:2017-08-29 Online:2019-10-18 Published:2019-10-23
  • Contact: Hong-tian LI,Jian-meng LIU E-mail:liht@bjmu.edu.cn;liujm@pku.edu.cn
  • Supported by:
    Supported by the National Key(2016YFC1000401);the Wyeth Nutrition Research Program

RICH HTML

  

摘要:

目的:描述中国新生儿出生特征,并评价应用移动终端采集妇幼健康基础信息和开展相关流行病学研究的可行性。方法:2016年6月至2017年1月,在全国23个省份166家助产机构募集孕产妇,应用手机终端自填式问卷采集分娩方式、孕周和出生体质量等基础信息,描述剖宫产、早产、出生体质量、身长和头围等常用妇幼健康指标的发生率或平均水平。与2005年中国7岁以下儿童生长发育标准、2006年世界卫生组织儿童生长发育标准以及2014年中国不同胎龄新生儿出生体质量标准比较,评价数据的可信性。结果:调查产妇9 986名,其中35岁及以上者占11.7%,大专及以上学历者占70.2%。剖宫产、早产、低出生体重儿和巨大儿的发生率依次为38.1%、4.5%、2.2%和7.8%;新生儿平均出生体质量(3.33±0.44) kg [男(3.36±0.44) kg,女(3.29±0.43) kg],身长(50.97±2.32) cm [男(51.04±2.32) cm,女(50.89±2.32) cm],头围(33.99±1.56) cm [男(34.01±1.57) cm,女(33.97±1.55) cm]。与不同时期全国数据比较显示,剖宫产率和足月儿胎龄别出生体质量接近2014年全国水平,平均出生体质量和身长高于2005年中国生长发育标准、也高于2006年世界卫生组织生长发育标准。结论:男、女婴出生体质量较10年前的全国数据分别增加40 g和80 g,身长分别增加0.6 cm和1.3 cm,头围则与10年前相近,提示10年来我国新生儿体质状况明显改善,同时,信息化的发展可能为流行病学研究提供新途径。

关键词: 流行病学, 妇幼卫生, 新生儿, 移动终端, 数据收集

Abstract:

Objective: To describe the birth characteristics for Chinese newborns, to assess the feasibility of collecting basic data on maternal and child health, and to conduct relevant epidemiological studies by using mobile terminals. Methods: From June 2016 to January 2017, pregnant women who delivered in hospitals were recruited in 166 hospitals scattered across 23 provinces of China. The data on their maternal and child health including delivery mode, gestational age and birth weight, were collected by self-administered questionnaires embedded in a mobile application. The incidences or means of cesa-rean section, preterm birth, birth weight, length and head circumference were calculated and compared with recognized national data, including 2005 Growth Standards for Chinese Children Under 7 Years of Age, 2006 World Health Organization Child Growth Standards and 2014 Chinese Neonatal Birth Weight Standards by Gestational Age. Results: A total of 9 986 women were investigated, among whom those aged ≥35 years accounted for 11.7% and those received well education (college and above) accounted for 70.2%. The rate of cesarean section, preterm delivery, low birth weight and macrosomia were 38.1%, 4.5%, 2.2%, and 7.8%, respectively. The means were (3.33±0.44) kg [male (3.36±0.44) kg, female (3.29±0.43) kg] for birth weight, (50.97±2.32) cm [male (51.04±2.32) cm, female (50.89±2.32) cm] for birth length, and (33.99±1.56) cm [male (34.01±1.57) cm, female (33.97±1.55) cm] for head circumference, respectively. As compared with the national data, the cesarean section rate and birth weights by gestational age for term-born neonates were similar to the latest national data in 2014, while the means of birth weight and length were obviously higher than those of the 2005 Growth Standards for Chinese Children Under 7 Years of Age and 2006 World Health Organization Child Growth Standards. Conclusion: As compared with the national data 10 years ago, the mean birth weights for male and female newborns were increased by 40 g and 80 g respectively and mean lengths by 0.6 cm and 1.3 cm, but changes for mean head circumferences were negligible, indicating that the physical health condition for Chinese newborns improved significantly over past 10 years and emerging information technology likely provided a new approach for epidemiological research.

Key words: Epidemiology, Maternal and child health, Newborn, Mobile terminal, Data collection

中图分类号: 

  • R174

表1

产妇及新生儿基本情况"

Items Number Proportion/%
Maternal age/years*
≤19 89 1.0
20-34 7 743 87.3
≥35 1 039 11.7
Education*
College and above 5 790 70.2
High school 1 343 16.3
Middle school or below 1 117 13.5
Parity
First 6 046 60.5
Second 3 607 36.1
Third and above 333 3.3
Hospital level
Tertiary 6 247 62.6
Secondary 3 196 32.0
Primary 543 5.4
Economic regions
East 6 200 62.1
Middle 1 641 16.4
West 2 145 21.5
Neonatal gender
Male 5 646 56.5
Female 4 340 43.5

表2

不同经济地区的产妇特征分布"

Items East, n (%) Middle, n (%) West, n (%)
Maternal age/years*
≤19 55 (1.1) 11 (0.7) 23 (1.1)
20-34 4 458 (86.7) 1 361 (84.6) 1 924 (90.7)
≥35 628 (12.2) 236 (14.7) 175 (8.3)
Education*
College and above 3 153 (65.4) 1 089 (76.2) 1 548 (77.4)
High school 860 (17.8) 201 (14.1) 282 (14.1)
Middle school or below 807 (16.7) 139 (9.7) 171 (8.6)
Parity
First 3 602 (58.1) 943 (57.5) 1 501 (70.0)
Second 2 353 (38.0) 638 (38.9) 616 (28.7)
Third and above 245 (4.0) 60 (3.7) 28 (1.3)
Hospital level
Tertiary 3 845 (62.0) 1 227 (74.8) 1 175 (54.8)
Secondary 1 862 (30.0) 414 (25.2) 920 (42.9)
Primary 493 (8.0) 0 (0) 50 (2.3)

表3

主要妇幼健康指标发生率"

Items Cesarean section, n (%) Preterm birth, n (%) Low birth weight, n (%) Macrosomia, n (%)
Overall 3 802 (38.1) 452 (4.5) 218 (2.2) 780 (7.8)
Maternal age/years
≤19 23 (25.8)# 8 (9.0)# 3 (3.4) 5 (5.6)
20-34 2 707 (35.0) 326 (4.2) 158 (2.0) 597 (7.7)
≥35 564 (54.3) 70 (6.7) 28 (2.7) 90 (8.7)
Education
College and above 2 061 (35.6)# 214 (3.7)# 94 (1.6)# 428 (7.4)
High school 548 (40.8) 81 (6.0) 40 (3.0) 117 (8.7)
Middle school or below 422 (37.8) 73 (6.5) 43 (3.9) 94 (8.4)
Parity
Primipara 1 960 (32.4)# 252 (4.2)* 125 (2.1) 469 (7.8)
Multipara 1 842 (46.8) 200 (5.1) 93 (2.4) 311 (7.9)
Economic regions
East 2 451 (39.5)# 305 (4.9)* 150 (2.4) 526 (8.5)#
Middle 652 (39.7) 58 (3.5) 25 (1.5) 120 (7.3)
West 699 (32.6) 89 (4.2) 43 (2.0) 134 (6.3)
Hospital level
Tertiary 2 493 (39.9)# 281 (4.5) 132 (2.1) 493 (7.9)
Secondary and below 1 309 (35.0) 171 (4.6) 86 (2.3) 287 (7.7)
Neonatalgender
Male 2 088 (37.0)* 264 (4.7) 107 (1.9)* 511 (9.1)#
Female 1 714 (39.5) 188 (4.3) 111 (2.6) 269 (6.2)

表4

与2005年中国生长发育标准和2006年WHO生长发育标准的比较"

Items Male Female
Birth weight/kg Length/cm Head circumference/cm Birth weight/kg Length/cm Head circumference/cm
This survey 3.36±0.44 51.0±2.3 34.0±1.6 3.29±0.43 51.0±2.3 34.0±1.6
2005 Chinese Standards 3.32±0.39* 50.4±1.8* 34.5±1.2* 3.21±0.39* 49.7±1.7* 34.0±1.2
2006 WHO Standards 3.35±0.49* 49.9±1.9* 34.5±1.3* 3.23±0.46* 49.1±1.9* 33.9±1.2*

图1

足月儿胎龄别出生体质量与我国1987年及2014年出生体质量标准比较"

[1] Li HT, Luo S, Trasande L , et al. Geographic variations and temporal trends in cesarean delivery rates in China, 2008—2014[J]. JAMA, 2017,317(1):69-76.
[2] 朱丽, 张蓉, 张淑莲 , 等. 中国不同胎龄新生儿出生体重曲线研制[J]. 中华儿科杂志, 2015,53(2):97-103.
[3] 首都儿科研究所, 九市儿童体格发育调查协作组. 中国七岁以下儿童体重、身长/身高和头围的生长标准值及标准化生长曲线[J]. 中华儿科杂志, 2009,47(3):173-178.
[4] 赖建强, 荫士安, 马冠生 , 等. 我国婴幼儿出生与喂养状况调查研究[J]. 营养学报, 2006,28(1):4-7.
[5] Chan YY, Wang P, Rogers L , et al. The asthma mobile health study, a large-scale clinical observational study using ResearchKit[J]. Nat Biotechnol, 2017,35(4):354-362.
[6] 乐杰 . 妇产科学[M]. 北京: 人民卫生出版社, 2008: 86-125.
[7] 中华人民共和国国家统计局. 中国农业碳排放的结构特征及时空差异研究[EB/OL]. ( 2016- 09- 21) [2017-12-13]. .
[8] WHO Multicentre Growth Reference Study Group. WHO child growth standards: Length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: Methods and development[M]. Geneva: World Health Organization, 2006: 13-138.
[9] WHO Multicentre Growth Reference Study Group. WHO child growth standards: Head circumference-for-age, arm circumference-for-age, triceps skinfold-for-age and subscapular skinfold-for-age: Methods and development[M]. Geneva: World Health Organization, 2007: 7-55.
[10] 张宝林 . 中国15城市不同胎龄男女新生儿出生体重值修正报告[J]. 中国实用儿科杂志, 1992,7(6):306-307.
[11] Lumbiganon P, Laopaiboon M, Gulmezoglu AM , et al. Method of delivery and pregnancy outcomes in Asia: the WHO global survey on maternal and perinatal health 2007-08[J]. Lancet, 2010,375(9713):490-499.
[12] 侯磊, 李光辉, 邹丽颖 , 等. 全国剖宫产率及剖宫产指征构成比调查的多中心研究[J]. 中华妇产科杂志, 2014,49(10):728-735.
[13] 崔好胜, 李宏田, 朱丽萍 , 等. 1993—2005年中国南方部分地区经产妇剖宫产和孕妇要求剖宫产率变化趋势[J]. 北京大学学报(医学版), 2013,45(3):422-426.
[14] 邓松清, 陈海天, 王冬昱 , 等. 二孩政策前后剖宫产率及剖宫产指征变化[J]. 中华围产医学杂志, 2017,20(1):47-50.
[15] 张亚钦, 李辉 . 我国初生儿体格发育水平30年变化[J]. 中华围产医学杂志, 2011,14(11):660-665.
[16] Blencowe H, Cousens S, Oestergaard MZ , et al. National, regio-nal, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a syste-matic analysis and implications[J]. Lancet, 2012,379(9832):2162-2172.
[17] 杨惠娟, 于莹, 刘凯波 , 等. 二胎政策放开对北京市早产儿发生率及结局的影响分析[J]. 中国妇幼保健, 2017,32(1):10-12.
[18] 刘兰, 刘建蒙, 刘英惠 , 等. 中国10县(市)1993—2005年单胎儿早产流行状况研究[J]. 中华流行病学杂志, 2007,28(11):1051-1054.
[19] 中华人民共和国国家统计局. 2016年国民经济实现“十三五”良好开局[EB/OL]. ( 2017- 01- 20) [2017-12-13]. .
[20] 谭琳, 蒋永萍, 姜秀花 . 2008—2012年:中国性别平等与妇女发展报告 [M]. 北京: 社会科学文献出版社, 2013: 51-52.
[21] 陈芳芳, 滕红红, 滕越 , 等. 北京城区1996—2010年多胎妊娠变化趋势及妊娠结局[J]. 中华流行病学杂志, 2014,35(3):276-279.
[22] 杜晓娜 . 2009—2011年北京市中心城区以人群为基础的出生缺陷流行病学分析[J]. 中国生育健康杂志, 2014,25(4):374-375.
[1] 王子恺,莫佳丽,张蒙,廖纪萍. 2013—2020年北京市慢性阻塞性肺疾病急性加重女性住院患者的流行病学和住院费用分析[J]. 北京大学学报(医学版), 2023, 55(6): 1074-1081.
[2] 王哲,孙伟,杨雪,宋颖,姬爱平,白洁. 口腔急诊颌面部感染患者临床分析[J]. 北京大学学报(医学版), 2023, 55(3): 543-547.
[3] 姚晓莹,刘志科,李宁,马瑞,赵薛飞,张良,许国章,詹思延,方挺. 2015—2019年宁波市0~36月龄婴幼儿癫痫发病的流行病学研究[J]. 北京大学学报(医学版), 2021, 53(3): 485-490.
[4] 董彦会,陈曼曼,王丽萍,星一,宋逸,邹志勇,董彬,李中杰,马军. 中国6~22岁学生群体甲乙丙类传染病流行趋势[J]. 北京大学学报(医学版), 2021, 53(3): 498-505.
[5] 李秀翠,周玉博,司可艺,李宏田,张乐,张亚黎,刘菊芬,刘建蒙. 孕晚期妇女与新生儿血浆维生素A水平的相关性分析[J]. 北京大学学报(医学版), 2020, 52(3): 464-469.
[6] 邓思危,陈则亦,刘志科,王健,卓琳,高双庆,余家阔,詹思延. 基于城镇医保数据库骨关节伤病的流行病学研究[J]. 北京大学学报(医学版), 2020, 52(3): 527-534.
[7] 李宁宁,季丽娜,晁爽,袁珂,孟洪,黄振宇,张华斌. 新生儿先天性肾脏和泌尿道畸形的超声筛查及随访[J]. 北京大学学报(医学版), 2019, 51(6): 1062-1066.
[8] 刘园,栾庆先. 北京石景山社区中老年人群慢性牙周炎和颈动脉内膜中层厚度的相关性[J]. 北京大学学报(医学版), 2018, 50(2): 264-270.
[9] 李宁,刘昊楠,龚晓峰,朱仕文,吴新宝,贺良. 北京某三甲医院股骨颈骨折住院患者现状的流行病学分析[J]. 北京大学学报(医学版), 2016, 48(2): 292-296.
[10] 周玉博, 罗树生, 李宏田, 高燕秋, 刘建蒙. 1996年至2013年中国婚前医学检查率变化情况[J]. 北京大学学报(医学版), 2015, 47(3): 437-442.
[11] 孙丽娜, 陈亚红, 沈宁, 路明, 姚婉贞. 慢性阻塞性肺疾病新病情评估方法的分布及意义[J]. 北京大学学报(医学版), 2014, 46(4): 662-667.
[12] 李恒, 黄悦勤, 马亚婷, 刘肇瑞. 中国归因于非痴呆器质性精神障碍残疾的描述性流行病学研究[J]. 北京大学学报(医学版), 2014, 46(2): 247-253.
[13] 邓秋菊,潘雅琪,王朝义,李凤垒,吕绍江,胡绍用,宁涛,郭传海,何忠虎,柯杨. 河南滑县农村地区成人乙型肝炎表面抗原检出率及相关因素分析[J]. 北京大学学报(医学版), 2013, 45(6): 965-970.
[14] 周文娟, 梁爱民, 王凤芝, 崔文红, 王秀云, 刘秋明, 游红, 贺春燕, 彭金荣, 张迎武, . 北京市四区/县18月龄儿童发育迟缓的流行病学研究[J]. 北京大学学报(医学版), 2013, 45(2): 211-.
[15] 詹思延. 药物流行病学理论和方法的发展[J]. 北京大学学报(医学版), 2013, 45(03): 343-346.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!