腮腺和颌下腺体积的测量

摘要/Abstract

摘要： 目的：精确测量正常腮腺和颌下腺体积，建立其正常值，并将其应用于IgG4相关唾液腺炎腺体肿大的诊断。方法：参照中华医学会老年医学会和WHO(2000年)提出的年龄分组标准，通过CT容积重建的方法，测量240例受检者正常腮腺和颌下腺的体积，得出不同性别和年龄组正常值。测量30例IgG4相关唾液腺炎患者肿大的腮腺和颌下腺体积，并与正常值范围相比较。结果：CT容积重建方法用于测量腮腺和颌下腺的体积具有较好的重复性。可得出不同年龄和性别人类腮腺和颌下腺体积正常值范围，其中腮腺正常值(95%CI)为：青少年组男性16.993~20.975 cm³，女性13.908~16.696 cm³；青年组男性20.015~24.359 cm³，女性18.089~21.135 cm³；中年组男性28.638~35.122 cm³，女性19.588~22.474 cm³；年轻老年及老年组男性28.792~35.082 cm³，女性 28.783~34.909 cm³。颌下腺正常值(95%CI)为：青少年组男性7.202~8.852 cm³，女性6.494~8.126 cm³；青年组男性7.759~9.523 cm³，女性7.285~8.605 cm³；中年组男性8.423~10.177 cm³，女性7.905~9.309 cm³；年轻老年及老年组男性8.310~10.510 cm³，女性7.003~8.203 cm³。随着年龄的增加, 腮腺体积逐渐增加，颌下腺体积变化不明显。IgG4相关唾腺炎患者腮腺和颌下腺肿大时其体积与同年龄、同性别组正常值相比明显增加。结论： CT容积重建的方法可以精确测量腮腺和颌下腺的体积，本研究建立的不同年龄和性别组人腮腺和颌下腺体积的正常值可应用于腮腺和颌下腺肿大的诊断。

关键词: 腮腺, 颌下腺, 唾液腺炎, 体积, 体层摄影术, X线计算机

Abstract: Objective：To accurately measure the volume of normal human parotid and submandibular glands, establish the normal values of the volumes of the glands, and apply the technique in the diagnosis of swollen salivary glands of the patients with IgG4-related sialadenitis.Methods:Two hundred and forty cases with normal parotid and submandibular glands who received CT examination were divided into 4 groups according to the age standards raised by the Society of Geriatrics Chinese Medical Association and WHO (2000) age standards . 3D CT images of parotid and submandibular glands were reconstructed by technique of volume rendering. Volumes of normal parotid and submandibular glands were measured and their normal values were analyzed. The volumes of swollen parotid and submandibular glands from 30 cases with IgG4 -related sialadenitis were compared with the normal values. Results：3D images of parotid and submandibular glands were well established by volume rendering. The normal values（95%confidence interval, 95%CI） of CT volume of parotid gland were as follows: adolescent group of males: 16.993-20.975 cm³, females: 13.908-16.696 cm³; young group of males: 20.015-24.359 cm³, females: 18.089-21.135 cm³; middle-aged group of males: 28.638-35.122 cm³, females: 19.588-22.474 cm3; young elderly and elderly group of males: 28.792-35.082 cm3, females: 28.783-34.909 cm³. The normal values （95%CI） of submandibular gland were as follows: adolescent group of males: 7.202-8.852 cm³, females: 6.494-8.126 cm³; young group of males: 7.759-9.523 cm³, females: 7.285-8.605 cm³; middleaged group of males: 8.423-10.177 cm³, females: 7.905-9.309 cm³; young elderly and elderly group of males: 8.310-10.510 cm³, females: 7.003-8.203 cm³. The volumes of parotid glands increased with age. but no significant change was found in those of submandibular glands. The volumes of the swollen glands from the patients with IgG4 -related sialadenitis were significantly larger than those of the normal glands.Conclusion：Volumes of the parotid and submandibular glands could be definitely and quantitively measured by CT volume rendering. The established normal values in this study could be taken as the reference for the diagnosis of parotid and submandibular gland enlargement .

Key words: Parotid gland, Submandibular gland, Sialdenitis, Volume, Tomograpphy, X-ray computed

李巍, 孙志鹏, 刘筱菁, 俞光岩. 腮腺和颌下腺体积的测量[J]. 北京大学学报（医学版）, 2014, 46(2): 288-293.

LI Wei, SUN Zhi-Peng, LIU Xiao-Jing, YU Guang-Yan. Volume measurements of human parotid and submandibular glands[J]. Journal of Peking University(Health Sciences), 2014, 46(2): 288-293.

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