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北京大学学报（医学版） ›› 2020, Vol. 52 ›› Issue (4): 762-770. doi: 10.19723/j.issn.1671-167X.2020.04.031

• 论著 • 上一篇    下一篇

一种数字化全口义齿的临床疗效评价

魏菱1,邹东2,陈虎1,潘韶霞1,△(),孙玉春1,△(),周永胜1   

  1. 1.北京大学口腔医学院·口腔医院,修复科 国家口腔疾病临床医学研究中心 口腔数字化医疗技术和材料国家工程实验室 口腔数字医学北京市重点实验室,北京 100081
    2.中日友好医院口腔医学中心,北京 100029
  • 收稿日期:2019-09-19 出版日期:2020-08-18 发布日期:2020-08-06
  • 通讯作者: 潘韶霞,孙玉春 E-mail:panshaoxia@vip.163.com;polarshining@163.com
  • 基金资助:
    首都卫生发展科研专项(2016-1-4101);北京大学口腔医院临床新技术新疗法项目(PKUSSNCT-15A09)

Evaluation of clinical efficacy of a kind of digital complete denture

Ling WEI1,Dong ZOU2,Hu CHEN1,Shao-xia PAN1,△(),Yu-chun SUN1,△(),Yong-sheng ZHOU1   

  1. 1. Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China
    2. Centre of Stomatology, China-Japan Friendship Hospital, Beijing 100029, China
  • Received:2019-09-19 Online:2020-08-18 Published:2020-08-06
  • Contact: Shao-xia PAN,Yu-chun SUN E-mail:panshaoxia@vip.163.com;polarshining@163.com
  • Supported by:
    Capital Health Research and Development of Special(2016-1-4101);Program for New Clinical Techniques and Therapies of Peking University School and Hospital of Stomatology(PKUSSNCT-15A09)

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摘要：

目的: 比较计算机辅助设计与制造(computer aided design/computer aided manufacturing,CAD/CAM)技术制作的数字化全口义齿与传统方法制作的全口义齿的临床疗效。方法: 纳入20例无牙颌患者,通过前瞻性、单盲、自身对照临床实验,每人分别采用功能易适性数字化义齿(functional suitable denture, FSD)制作系统及传统方法制作全口义齿。义齿完成后,首先戴用传统全口义齿, 3个月后交换戴用数字化全口义齿。患者于修复前、修复后第2周、第1个月、第2个月、第3个月填写无牙颌口腔健康影响量表-20(oral health impact profile edentulous,OHIP-20E)和义齿满意度视觉模拟评分量表(visual analogue scale,VAS)。于两副义齿戴用后的第3个月,分别进行咀嚼效率测试。结果: 20例患者在戴牙后第3个月,FSD全口义齿VAS评分在总体满意度、易清洁性、发音、美观、稳定、口腔状况这6个方面均值均高于传统全口义齿,而在舒适、咀嚼能力、嚼碎功能这3个方面VAS评分的均值与传统全口义齿基本持平,但差异无统计学意义(P>0.05);FSD全口义齿OHIP-20E评分在各个方面的均值均高于传统全口义齿,其中功能受限、心理不适、总评分这3个方面评分差异有统计学意义(P<0.05);咀嚼效率测量结果为,FSD全口义齿平均咀嚼效率(1.20±0.54)高于传统全口义齿的平均咀嚼效率(1.16±0.53), 差异无统计学意义(P=0.691)。结论: 本研究评价的数字化全口义齿的疗效与传统全口义齿相同,在患者满意度及口腔相关生活质量评价方面都展现出相同的治疗效果。

关键词: 计算机辅助设计与制造, 功能易适性数字化义齿系统, 全口义齿, 临床疗效

Abstract:

Objective: To compare the clinical efficacy of a kind of complete dentures fabricated using computer aided design/computer aided manufacturing (CAD/CAM) workflow with that of the complete denture fabricated using conventional workflow. Methods: Twenty edentulous patients were included in this prospective, single-blind, self-controlled clinical trial. Two pairs of complete dentures were fabricated for each participant: one using the functional suitable denture (FSD) system with CAD/CAM, and the other using conventional fabrication workflow. In the final delivery appointment, the conventional dentures worn by the participant for 3 months at first. Then the participant swapped to wear digital denture for another 3 months. The patients’ satisfaction and oral health related quality of life (OHRQoL) were measured using the visual analogue scale (VAS) and oral health impact profile (OHIP-20E) at baseline, 2 weeks, 1 month, 2 months, and 3 months following denture delivery. In addition, the masticatory efficiency of each pair of dentures was measured after three months adaptation period for each type of dentures. Results: The VAS scores of the twenty patients in FSD denture group on general satisfaction, ease of cleaning, ability to speak, esthetics, stability and oral health status on these six domains were higher than that of conventional denture group 3 months after delivery. While the VAS cores in FSD denture group on comfort, ability to chew and ability to chew up were the same as those of conventional denture group. But there was no significant difference (P>0.05). The VAS score on each domain in FSD denture group was higher than that of conventional denture group 3 months after delivery, three domains of which reached statistical significance (P<0.05), involving functional limitation, psychological discomfort and total. The masticatory performance of the FSD denture (1.20±0.54) was slightly higher than that for the conventional denture (1.16±0.53), but the difference did not reach statistical significance (P=0.691). Conclusion: The clinical efficacy of the FSD complete denture is comparable to that of the conventional complete denture. As for patient satisfaction and oral health related quality of life, FSD dentures received comparable scores as conventional complete dentures did.

Key words: Computer aided design/computer aided manufacturing, Functional suitable denture system, Complete denture, Clinical efficacy

中图分类号: 

  • R783.2

图1

FSD全口义齿与传统全口义齿临床疗效比较的实验设计流程图"

图2

基线与戴用FSD全口义齿后2周、1个月、2个月、3个月各方面VAS得分对比图"

图3

基线与戴用传统全口义齿后2周、1个月、2个月、3个月各方面VAS得分对比图"

图4

各观察时点患者戴用FSD和传统全口义齿总体义齿满意度VAS评分"

图5

OHIP-20E基线与戴FSD全口义齿后2周、1个月、2个月及3个月各分项得分对比图"

图6

OHIP-20E基线与戴传统全口义齿后2周、1个月、2个月及3个月各分项得分对比图"

图7

20例患者分别戴用两种全口义齿各观察时间节点OHIP-20E总评分"

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