北京大学学报(医学版) ›› 2022, Vol. 54 ›› Issue (1): 77-82. doi: 10.19723/j.issn.1671-167X.2022.01.012

• 论著 • 上一篇    下一篇

常温流动牙胶应用于根尖诱导成形术后根管充填

闫文娟,钟洁,林碧琛,丁美丽,陈小贤()   

  1. 北京大学口腔医学院·口腔医院门诊部,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔数字化医疗技术和材料国家工程实验室,口腔数字医学北京市重点实验室,北京 100081
  • 收稿日期:2021-10-11 出版日期:2022-02-18 发布日期:2022-02-21
  • 通讯作者: 陈小贤 E-mail:chenxiaox2007@126.com

Application of cold flowable gutta-percha in root canal obturation after apexification

YAN Wen-juan,ZHONG Jie,LIN Bi-chen,DING Mei-li,CHEN Xiao-xian()   

  1. First Clinical Division, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China
  • Received:2021-10-11 Online:2022-02-18 Published:2022-02-21
  • Contact: Xiao-xian CHEN E-mail:chenxiaox2007@126.com

RICH HTML

  

摘要:

目的: 评价常温流动牙胶应用于年轻恒牙根尖诱导成形术后根管充填的临床效果。方法: 选择2020年4—10月在北京大学口腔医院门诊部儿童口腔科就诊因年轻恒牙牙髓坏死或根尖周病变经过完善的根尖诱导成形术治疗的病例,共收集到病例90例,随机分为两组,试验组和对照组各45例。试验组采用常温流动牙胶充填系统,对照组采用热牙胶充填系统进行根管充填,记录每根管的根管充填时间,由患儿监护人填写VAS(visual analog scales)视觉模拟评分量表评估治疗疼痛程度,术后即刻拍摄X线片,评价根管充填效果,并分别对根管下段、中段、上段的三维充填严密程度进行分析,术后6个月、12个月进行临床检查并拍摄X线片判断治疗成功率。结果: 试验组平均每根管充填时间明显低于对照组,分别为51 s和 74 s,组间比较差异有统计学意义(P<0.05);两组疼痛发生率分别为26.67%和40.00%;试验组和对照组的根管充填恰填且三维充填严密率分别为71.11%和60.00%;根尖1/3区域三维充填严密率为86.67%和66.67%,组间差异有统计学意义(P<0.05),根中1/3及根上1/3根管充填的三维严密性两组间差异无统计学意义;1年复查期内两组均未见根尖病变。结论: 常温流动牙胶应用于年轻恒牙根尖诱导成形后根管充填可取得良好的根管充填效果,根尖1/3区域的根管充填效果优于热牙胶,常温流动牙胶能够缩短临床治疗时间,改善患儿的舒适度。

关键词: 常温流动牙胶, 根管充填, 年轻恒牙, 根尖诱导成形术

Abstract:

Objective: To evaluate the clinical effect of root canal obturation therapy using cold flowable gutta-percha on young permanent teeth after apexification. Methods: Ninety cases of young permanent teeth with pulp necrosis or periapical periodontitis treated by apexification were randomly divided into two groups. The cases in each group were divided into single root canal and multiple root canal according to the number of the root canal, and divided into classifications Ⅰ, and Ⅱ/Ⅲ/Ⅳ according to Frank’s classification of root development after apexification. Cold flowable gutta-percha and warm gutta-percha obturation techniques were used for root canal obturation of the two groups. The operation time was recorded, and the patients’ therapy pain degree was evaluated by visual analog scale (VAS) immediately after operation. Periapical X-ray was performed after operation to evaluate the effect of the root canal filling. The total length of the root was divided into equal three parts on the X-ray film, and three-dimensional tightness of the apical, middle, and coronal region of the root canals were statistically analyzed respectively. Clinical examinations and X-ray examination were performed 6 and 12 months after the operation to evaluate the treatment success rate. Results: The operation time of cold flowable gutta-percha group was significantly lower than that of the control group, which were 51 s and 74 s (P<0.05); The percentages of pain and discomfort in the two groups were 26.67% and 40.00%, respectively. There were two cases of underfilling and no overfilling in both groups. The percentages of proper filling and tight three-dimensional obturation in the experimental and control groups were 71.11% and 60.00% respectively; and the percentages of tight three-dimensional obturation in the apical third areas were 86.67% and 66.67%, the difference was significant (P<0.05). There was no significant difference in the three-dimensional tightness between the two groups in the middle and coronal third areas. The percentages of tight three-dimensional obturation in classification Ⅰ groups were 86.67%, 83.33%, 93.33% and 76.67%, 90.00%, 96.67% in experimental and control group, respectively; The percentages of classification Ⅱ/Ⅲ/Ⅳ groups were 86.67%, 86.67%, 100.00% and 46.67%, 86.67%, 100.00%, respectively, and the difference was significant (P<0.05). There were no apical lesions that occurred in either group during the one-year review period. Conclusion: The application of cold flowable gutta-percha on young permanent teeth root canal obturation after apexification can achieve good obturation effect. The root obturation effect in the apical third area is significantly better than that of warm gutta-percha obturation techniques. Cold flowable gutta-percha can shorten the clinical treatment time and ameliorate the patients’ therapy comfort.

Key words: Cold flowable gutta-percha, Root canal obturation, Young permanent teeth, Apexification

中图分类号: 

  • R783.1

图1

根管充填治疗效果评价"

表1

根管平均充填时间($\bar{x}\pm s$)"

Group Number of root canals Frank classification Total
Single canal Multiple canals Classification Ⅰ Classification Ⅱ/ Ⅲ/ Ⅳ
Experimental n
Time/s
28 17 30 15 45
53±11 49±6 52±10 51±11 51±10
Control n
Time/s
22 23 30 15 45
78±18 71±19 76±18 70±20 74±19

表2

组间疼痛指数比较"

Group VAS scores Total Average score and percentage of pain and discomfort cases
0 1 2 3 4 5 6-10
Experimental, n (%) 33 (73.33) 5 (11.11) 3 (6.67) 3 (8.89) 1 (2.22) 0 (0.00) 0 (0.00) 45 0.533 (26.67)
Control, n (%) 27 (60.00) 7 (15.56) 5 (11.11) 4 (11.11) 1 (2.22) 1 (2.22) 0 (0.00) 45 0.844 (40.00)

表3

根管总充填质量"

Group Tight three-dimensional root canal obturation Underfilling Proper filling and tight
three-dimensional obturation
In the apical third
region of root canal
In the middle third
region of root canal
In the coronal third
region of root canal
Experimental, n (%) 39 (86.67) 38 (84.44) 43 (95.56) 2 (4.44) 32 (71.11)
Control, n (%) 30 (66.67) 40 (88.89) 44 (97.78) 2 (4.44) 27 (60.00)
P value 0.025* 0.535 0.557 1.000 0.267

表4

根管充填质量(按根管数量分类)"

Group number of
root canals
n Tight three-dimensional root canal obturation Underfilling Proper filling and tight three-dimensional obturation
In the apical third
region of root canal
In the middle third
region of root canal
In the coronal third
region of root canal
Experimental Single canal 28 24 (85.71) 24 (85.71) 26 (92.86) 2 (7.14) 20 (71.43)
Multiple canals 17 15 (88.24) 14 (82.35) 17 (100.00) 0 (0.00) 12 (70.59)
Control Single canal 22 17 (77.27) 18 (81.82) 22 (100.00) 1 (4.55) 15 (68.18)
Multiple canals 23 13 (56.52) 22 (95.65) 22 (95.65) 1 (4.35) 12 (52.17)
P value Single canal 0.441 0.709 0.201 0.701 0.418
Multiple canals 0.030* 0.166 0.384 0.384 0.150

表5

根管充填质量(按Frank分型分类)"

Group Frank
classification
N Tight three-dimensional root canal obturation Underfilling Proper filling and tight
three-dimensional obturation
In the apical third
region of root canal
In the middle third
region of root canal
In the coronal third
region of root canal
Experimental 30 26 (86.67) 25 (83.33) 28 (93.33) 2 (6.67) 24 (80.00)
Ⅱ/ Ⅲ/ Ⅳ 15 13 (86.67) 13 (86.67) 15 (100.00) 0 (0.00) 11 (73.33)
Control 30 23 (76.67) 27 (90.00) 29 (96.67) 2 (6.67) 20 (66.67)
Ⅱ/ Ⅲ/ Ⅳ 15 7 (46.67) 13 (86.67) 15 (100.00) 0 (0.00) 7 (46.67)
P value 0.317 0.448 0.554 1.000 0.243
Ⅱ/ Ⅲ/ Ⅳ 0.020* 1.000 1.000 1.000 0.136
[1] Frank AL. Therapy for the divergent pulpless tooth by continued apical formation[J]. J Am Dent Assoc, 1966, 72(1):87-93.
pmid: 5215726
[2] Sheehy EC, Roberts GJ. Use of calcium hydroxide for apical barrier formation and healing in non-vital immature permanent teeth: A review[J]. Br Dent J, 1997, 183(7):241-246.
doi: 10.1038/sj.bdj.4809477
[3] Adhikari HD, Jain S. Scanning electron microscopic evaluation of marginal adaptation of AH-Plus, GuttaFlow, and RealSeal at apical one-third of root canals: Part Ⅱ: Core-sealer interface[J]. J Conserv Dent, 2018, 21(1):90-94.
[4] Gandolfi MG, Siboni F, Prati C. Properties of a novel poly-siloxane-guttapercha calcium silicate-bioglass-containing root canal sealer[J]. Dent Mater, 2016, 32(5):113-126.
doi: 10.1016/j.dental.2016.03.001 pmid: 27037059
[5] Rafter M. Apexification: A review[J]. Dent Traumatol, 2005, 21(1):1-8.
pmid: 15660748
[6] 陈光, 仇珺, 胡斌. 常温流动牙胶 GuttaFlow 用于磨牙根管治疗术一次法的疗效研究[J]. 牙体牙髓牙周病学杂志, 2014, 24(9):542-544.
[7] Katarzyna O, Halina P. Evaluation of the sealing ability of three obturation techniques using a glucose leakage test[J]. Biomed Res Int, 2017, 6(19):1-8.
[8] Zielinski TM, Baumgartner JC, Marshall JG. An evaluation of GuttaFlow and Gutta-Percha in the filling of lateral grooves and depressions[J]. J Endod, 2008, 34(3):295-298.
doi: 10.1016/j.joen.2007.12.004
[9] 黎景景, 陈苏蕾, 李俊亮. 4种充填方法对椭圆形根管根尖超填及封闭性能的影响[J]. 口腔医学研究, 2017, 33(10):4.
[10] Jain H, Ballal NV. Comparison between the use of thermoplasticized gutta-percha and a polydimethyl siloxane-based material in filling internal resorptive cavities using spiral computed tomography[J]. Microsc Res Tech, 2019, 82(2):149-152.
doi: 10.1002/jemt.v82.2
[11] 王津, 姬爱平. 常温流动牙胶根管充填效果的临床评价[J]. 上海口腔医学, 2009, 18(4):380-382.
[12] Punjabi M, Dewan RG, Kochhar R. Comparative evaluation of fracture resistance of root canals obturated with four different obturating systems[J]. J Conserv Dent, 2017, 20(6):445-450.
doi: 10.4103/JCD.JCD_217_17
[13] Saygili G, Saygili S, Tuglu I, et al. In vitro cytotoxicity of GuttaFlow bioseal, GuttaFlow 2, AH-plus and MTA fillapex[J]. Iran Endod J, 2017, 12(3):354-359.
[14] Rodriguez-Lozano FJ, Collado-Gonzalez M, Tomas-Catala CJ, et al. GuttaFlow bioseal promotes spontaneous differentiation of human periodontal ligament stem cells into cementoblast-like cells[J]. Dent Mater, 2019, 35(1):114-124.
doi: 10.1016/j.dental.2018.11.003
[15] Nawal RR, Parande M, Sehgal R, et al. A comparative evaluation of antimicrobial efficacy and flow properties for epiphany, GuttaFlow and AH-plus sealer[J]. Int Endod J, 2015, 44(4):307-313.
doi: 10.1111/iej.2011.44.issue-4
[1] 何佩瑶,包旭东. 常温流动牙胶封闭剂GuttaFlow2单尖充填弯曲根管的封闭效果[J]. 北京大学学报(医学版), 2024, 56(1): 99-105.
[2] 郑佳佳,杨雪,温泉,付元,邵校,丁美丽. 生物活性陶瓷iRoot BP Plus®在儿童年轻恒前牙复杂冠折牙髓切断术中的应用[J]. 北京大学学报(医学版), 2024, 56(1): 179-184.
[3] 代云飞,刘鹤,彭楚芳,姜玺军. 年轻恒牙牙髓再生治疗术后36个月的临床疗效评估[J]. 北京大学学报(医学版), 2023, 55(4): 729-735.
[4] 王佳莎,王培育,梁宇红. 利用近场微波系统检测不同方法干燥根管的效果[J]. 北京大学学报(医学版), 2019, 51(6): 1124-1129.
[5] 陆瑾慧,钱军,刘鹤,朱俊霞. 富血小板纤维蛋白应用于年轻恒牙牙髓血运重建术的临床研究[J]. 北京大学学报(医学版), 2018, 50(4): 672-679.
[6] 臧海玲,王月,梁宇红. 有机溶剂对牙本质表面残留根管封闭剂的清除效果[J]. 北京大学学报(医学版), 2018, 50(1): 63-68.
[7] 安智广,渠薇,白伟,姜岚,梁宇红. 根管封闭剂X线阻射性的实验研究[J]. 北京大学学报(医学版), 2017, 49(2): 365-367.
[8] 范聪,袁重阳,张继川,王晓燕. 牙胶类根管充填材料导热性对根尖封闭的影响[J]. 北京大学学报(医学版), 2017, 49(1): 110-114.
[9] 乔迪, 董艳梅, 高学军. 体外评价新型根尖倒充填材料iRoot的生物学性能[J]. 北京大学学报(医学版), 2016, 48(2): 324-329.
[10] 渠薇,白伟,梁宇红,高学军. 热牙胶充填系统携热头工作状态下的实际温度[J]. 北京大学学报(医学版), 2015, 47(5): 834-837.
[11] 陈小贤, 林碧琛, 钟洁, 葛立宏. 改良乳牙根管充填材料体内降解匹配性与临床效果[J]. 北京大学学报(医学版), 2015, 47(3): 529-535.
[12] 卫彦, 严红, 马琦. 四种根管封闭剂的根尖封闭性研究[J]. 北京大学学报(医学版), 2008, 40(1): 71-73.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!