北京大学学报(医学版) ›› 2014, Vol. 46 ›› Issue (2): 215-219.

• 论著 • 上一篇    下一篇

2001年至2012年白内障术后眼内炎病例特点及视力转归回顾分析

吴元,晏晓明△   

  1. (北京大学第一医院眼科,北京100034)
  • 出版日期:2014-04-18 发布日期:2014-04-18

Retrospective analysis of the clinical characteristics and visual outcomes of postoperative endophthalmitis of cataract between 2001 and 2012

WU Yuan, YAN Xiao-ming△   

  1. (Department of Ophthalmology, Peking University First Hospital, Beijing 100034, China)
  • Online:2014-04-18 Published:2014-04-18

摘要: 目的:分析白内障术后眼内炎的临床特征、视力转归特点及影响因素。方法:收集本院眼科最近12年(2001年至2012年)白内障术后眼内炎的15例患者资料,总结疾病的发病率、发病时间、症状、临床体征、病原学特征等特点,分析病程中视力变化的规律以及影响本组病例视力转归的相关因素,以SPSS 14.0软件行统计学分析。结果:白内障术后眼内炎发病率为0.17%,平均发病时间23.8天(其中急性病例平均发病时间为6.0天),多数病例表现为严重的眼部炎症、眼部刺激征、视力下降。细菌培养阳性率为60%,均为G+菌(77%为表皮葡萄球菌)。经治疗后患者视力可有不同程度的提高,本组病例显示和视力转归有关的因素包括:白内障术后次日视力(r=0.746,P<0.01)、眼内炎发病时就诊视力(r=0.667,P<0.01)、术中后囊破裂(P<0.05)、眼部刺激征(P<0.05)等。结论:白内障术后眼内炎病例的视力转归受患者发生眼内炎后的视力情况、眼部症状是否严重、术中后囊是否破裂等因素的影响,相关病史可以对患者视力预后的判断提供参考信息。

关键词: 白内障, 眼内炎, 视觉

Abstract: Objective:To analyze the incidence, clinical characteristics and visual outcomes of postoperative endophthalmitis of cataract. Methods: Reviewed all the 15 electronic surgical records of cataract surgery during the last 12 years in Peking University First Hospital and summarized the incidence, onset time, symptoms, clinical signs and pathogenic characteristics of endophthalmitis. Analyzed the laws of vision changes and the related factors of visual outcomes. The data were analyzed with SPSS 14.0. Results: The overall rate of endophthalmitis was 0.17%, while most of the patients had serious symptoms and low vision. The onset time of the disease was 23.8 days on average, while that of the acute cases was 6 days. The positive rate of bacterial examination was 60% and all of the results were G+ (77% was Staphylococcus epidermidis). The visual acuity after treatment was improved to varying degrees. Our research had revealed that the factors related to the visual outcome included postsurgery visual acuity (r=0.746,P<0.01), presenting visual acuity at the onset of endophthalmitis (r=0.667,P<0.01), posterior capsular rupture occurrence (P<0.05) and ocular irritation symptoms (P<0.05). Conclusion: Better visual outcome of endophthalmitis after cataract surgery is correlated with positive and correct treatment. The vision and signs of the patients are useful to predict the visual outcomes.

Key words: Cataract, Endophthalmitis, Vision

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