北京大学学报(医学版) ›› 2014, Vol. 46 ›› Issue (6): 911-916.

• 论著 • 上一篇    下一篇

影响腹部外科术后重症患者脱离机械通气的心血管因素及非心血管因素分析

李纾1,安友仲1,任景怡2,朱凤雪1,陈红2△   

  1. (北京大学人民医院1.重症医学科,2.心内科,北京100044)
  • 出版日期:2014-12-18 发布日期:2014-12-18

Analysis of risk factors associated with weaning from mechanical ventilation in critical patients with major abdominal surgery

LI Shu1, AN You-zhong1, REN Jing-yi2, ZHU Feng-xue1, CHEN Hong2△   

  1. (1. Department of Critical Care Medicine, 2. Department of Cardiology, Peking University People’s Hospital, Beijing 100044, China)
  • Online:2014-12-18 Published:2014-12-18

摘要: 目的:分析影响腹部外科术后重症患者脱离机械通气(简称“脱机”)的心血管因素及非心血管因素,为临床决策提供参考。方法:回顾分析北京大学人民医院2011年1月至2013年12月间接受腹部外科手术并术后机械通气超过24 h的重症患者资料,利用统计学方法探索影响患者脱机成功率的心血管及非心血管相关危险因素,并分析脱机成功率对患者预后的影响。结果:共纳入患者381例,根据脱机成功与否将患者分为脱机成功组(n=274)和脱机失败组(n=107)。统计结果显示,高龄、术前左心室射血分数低、术后发生非心脏术后心肌损伤、脱机时血白蛋白偏低是影响脱机成功率的独立危险因素;脱机成功组住重症监护病房时间和28 d生存率均优于脱机失败组。结论:对于腹部术后机械通气超过24 h的重症患者而言,心血管因素包括术前左心功能障碍以及术后发生非心脏术后心肌损伤,其他因素包括高龄、脱机时血白蛋白偏低,是影响患者脱机成功率的独立危险因素。

关键词: 重症监护, 通气机撤除法, 腹部, 手术后医护, 危险因素

Abstract: Objective:To analyze the risk factors involved in the weaning from mechanical ventilation in critical patients who underwent major abdominal surgery. Methods: This retrospective study was conducted at Department of Critical Care Medicine in Peking University People’s Hospital. The subjects included all critical ill patients who underwent major abdominal surgery from January 2011 to December 2013. Clinical and laboratory parameters in perioperative period were investigated for the risk factors involved in the weaning from mechanical ventilation. Results: In this study, 381 patients were included, of whom, 274 were successfully weaned. We found old age, lower left ventricular ejection fraction (LVEF) before surgery, with the complication of myocardial injury after noncardiac surgery (MINS) and lower serum albumin level after surgery were the independent risk factors of weaning from mechanical ventilation. And the days of intensive care unit and 28-day mortality of patients who successfully weaned were better than patients who failed to wean. Conclusion: Old age, lower LVEF before surgery, with the complication of MINS and lower serum albumin level after surgery were independent risk factors of weaning in critical patients who underwent major abdominal surgery.

Key words: Intensive care, Ventilator weaning, Abdomen, Postoperative care, Risk factors

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