北京大学学报(医学版) ›› 2019, Vol. 51 ›› Issue (4): 775-777. doi: 10.19723/j.issn.1671-167X.2019.04.032

• 病例报告 • 上一篇    下一篇

肾癌及脑膜瘤术后并发吉兰-巴雷综合征1例

徐帅1,王旸烁2,李纾3,刘海鹰1,()   

  1. 1. 北京大学人民医院 脊柱外科, 北京 100044
    2. 北京大学人民医院 神经外科, 北京 100044
    3. 北京大学人民医院 重症医学科, 北京 100044
  • 收稿日期:2017-08-20 出版日期:2019-08-18 发布日期:2019-09-03
  • 通讯作者: 刘海鹰 E-mail:liuhaiying1131@sina.com

Guillain-Barre syndrome complicated on post-operation with renal carcinoma and meningioma: a case report

Shuai XU1,Yang-shuo WANG2,Shu LI3,Hai-ying LIU1,()   

  1. 1.Department of Spinal Surgery, Peking University People’s Hospital, Beijing 100044, China
    2. Department of Neurosurgery, Peking University People’s Hospital, Beijing 100044, China
    3. Department of Critical Care Medicine, Peking University People’s Hospital, Beijing 100044, China
  • Received:2017-08-20 Online:2019-08-18 Published:2019-09-03
  • Contact: Hai-ying LIU E-mail:liuhaiying1131@sina.com

RICH HTML

  

关键词: 吉兰-巴雷综合征, 肾癌, 脑膜瘤, 体位引流

Abstract:

Guillain-Barre syndrome (GBS) is an autoimmune disease on the injury of peripheral nerve myelin proteins or axon, of which the acute motor axonal neuropathy (AMAN) as a subtype is of infrequence and an extremely low incidence of post-operation. This article originally reported one case from Peking University People’s Hospital on successful treatment of severe GBS (AMAN) on post-operation with renal carcinoma and meningioma. The diagnostic criteria of AMAN refer to AIDP, of which the feature of AMAN suggests a pure motor nerve dysfunction and significant damage on motor axon. It is reported that infection and surgery may induce GBS. The positive result of IgM and IgG was considered the application of ganglioside and blood-brain barrier might be damaged after meningioma surgery which eased the drug to enter the cerebrospinal fluid circulation and induced lesions, therefore the etiology on this GBS case was of high confidence of administrating ganglioside drugs. Autonomic nerve dysfunctions, such as blood pressure fluctuations and arrhythmia could be caused in GBS, of which about 3%-10% of GBS patients would die. Early use of gamma globulin or plasma exchange was recommended interna-tionally, but recently some new ideas, to some extent, of significance on GBS treatment emerged. However, there was still no consensus on GBS treatment systematically all over the world. Till now, the general treatment program on GBS may be still gamma globulin or plasma exchange and a curious judgment of prognosis is essential in order to make a reasonable plan. That it was usually of no omen on severe autonomic nerve dysfunction must be successively monitored, the same as the management of the respiratory tract and nutrition support. The key measures taken on lung recruitment was postural drainage on this case with a low cost but a qualified effectiveness. This case report aimed to deepen the understanding of AMAN and acquaint the cutting-edge advances on the treatment of GBS, as well as providing successful treatment experience for the prevention on similar cases.

Key words: Guillain-Barre syndrome, Renal carcinoma, Meningioma, Postural drainage

中图分类号: 

  • R745.7

图1

体位引流改善肺不张X线片表现"

[1] Hartung HP, Willison HJ, Kieseier BC . Acute immunoinflammatory neuropathy: update on Guillain-Barre syndrome[J]. Curr Opin Neurol, 2002,15(5):571-577.
[2] Schonberger LB, Hurwitz ES, Katona P , et al. Guillain-Barre syndrome: its epidemiology and associations with influenza vaccination[J]. Ann Neurol, 1981,9(Suppl):31-38.
[3] Gensicke H, Datta AN, Dill P , et al. Increased incidence of Guillain-Barre syndrome after surgery[J]. Eur J Neurol, 2012,19(9):1239-1244.
[4] El-Bayoumi MA, El-Refaey AM, Abdelkader AM , et al. Com-parison of intravenous immunoglobulin and plasma exchange in treatment of mechanically ventilated children with Guillain-Barre syndrome: a randomized study[J]. Crit Care, 2011,15(4):R164.
[5] Algahtani H, Moulin DE, Bolton CF , et al. Guillain-Barre syndrome following cardiac surgery. Difficult diagnosis in the intensive care unit[J]. Neurosciences (Riyadh), 2009,14(4):374-378.
[6] Papantoni E, Sakorafas GH, Zouros E , et al. Guillain-Barre syndrome following total gastrectomy/esophagectomy:a very rare and dramatic post-operative complication with a favourable outcome[J]. ANZ J Surg, 2010,80(11):858.
[7] Hendawi T, Zavatsky JM . Guillain-Barre syndrome after pelvic fracture fixation: a rare cause of postoperative paralysis[J]. Spine (Phila Pa 1976), 2015,40(6):E372-E374.
[8] Yuki N, Hartung HP . Guillain-Barre syndrome[J]. N Engl J Med, 2012,366(24):2294-2304.
[9] Asbury AK, Cornblath DR . Assessment of current diagnostic criteria for Guillain-Barre syndrome[J]. Ann Neurol, 1990,27(Suppl):21-24.
[10] 中华医学会神经病学分会神经肌肉病学组, 中华医学会神经病学分会肌电图及临床神经电生理学组, 中华医学会神经病学分会神经免疫学组. 中国吉兰-巴雷综合征诊治指南[J]. 中华神经科杂志, 2010,43(8):583-586.
[11] Pithadia AB, Kakadia N . Guillain-Barre syndrome (GBS)[J]. Pharmacol Rep, 2010,62(2):220-232.
[12] Walgaard C, Lingsma HF, Ruts L , et al. Early recognition of poor prognosis in Guillain-Barre syndrome[J]. Neurology, 2011,76(11):968-975.
[13] 李胜 . 以麻痹性肠梗阻为首发表现的吉兰-巴雷综合征一例[J]. 中华急诊医学杂志, 2009,18(6):627.
[14] Ruts L, van Doorn PA, Lombardi R , et al. Unmyelinated and myelinated skin nerve damage in Guillain-Barre syndrome: correlation with pain and recovery[J]. Pain, 2012,153(2):399-409.
[15] 杨伟民, 方媛, 刘鸣 . 吉兰-巴雷综合征循证治疗进展[J]. 国际神经病学神经外科学杂志, 2008,35(3):258-260.
[16] Hughes RA, Swan AV, Raphael JC , et al. Immunotherapy for Guillain-Barre syndrome: a systematic review[J]. Brain, 2007,130(Pt 9):2245-2257.
[1] 舒帆,郝一昌,张展奕,邓绍晖,张洪宪,刘磊,王国良,田晓军,赵磊,马潞林,张树栋. 肾部分切除术治疗囊性肾癌的功能学和肿瘤学结果:单中心回顾性研究[J]. 北京大学学报(医学版), 2024, 56(4): 667-672.
[2] 张树栋,谢睿扬. 机器人手术时代的肾癌合并腔静脉瘤栓治疗策略[J]. 北京大学学报(医学版), 2024, 56(4): 562-564.
[3] 兰东,刘茁,李宇轩,王国良,田晓军,马潞林,张树栋,张洪宪. 根治性肾切除和静脉癌栓取出术大出血的危险因素[J]. 北京大学学报(医学版), 2023, 55(5): 825-832.
[4] 陈素华,杨军,陈新,杨辰龙,孙建军,林国中,于涛,杨欣,韩芸峰,吴超,司雨,马凯明. 大型、巨大型上矢状窦中后1/3侵犯颅外复发脑膜瘤的手术治疗[J]. 北京大学学报(医学版), 2022, 54(5): 1006-1012.
[5] 刘茁,朱国栋,唐世英,洪鹏,赵勋,张启鸣,李丽伟,彭冉,陈志刚,王滨帅,张丽,杨飞龙,葛力源,孙争辉,张树栋,王国良,田晓军,张洪宪,马潞林. 外科手术治疗年龄≥75岁的高龄肾细胞癌合并静脉癌栓患者的临床经验[J]. 北京大学学报(医学版), 2022, 54(4): 774-778.
[6] 秦彩朋,宋宇轩,丁梦婷,王飞,林佳兴,杨文博,杜依青,李清,刘士军,徐涛. 肾癌免疫治疗疗效评估突变预测模型的建立[J]. 北京大学学报(医学版), 2022, 54(4): 663-668.
[7] 洪鹏,田晓军,赵小钰,杨飞龙,刘茁,陆敏,赵磊,马潞林. 肾移植术后双侧乳头状肾癌1例[J]. 北京大学学报(医学版), 2021, 53(4): 811-813.
[8] 肖若陶,刘承,徐楚潇,何为,马潞林. 术前血小板参数与局部进展期肾细胞癌预后[J]. 北京大学学报(医学版), 2021, 53(4): 647-652.
[9] 李丽伟,刘茁,王国良,张华,陈文,马静,张丽,何为,马潞林,王淑敏. 肾癌伴下腔静脉瘤栓合并血栓的多种影像学比较[J]. 北京大学学报(医学版), 2019, 51(4): 678-683.
[10] 唐琦,林榕城,姚林,张争,郝瀚,张崔建,蔡林,李学松,何志嵩,周利群. 肾癌术后局部复发患者的临床病理特征及预后分析[J]. 北京大学学报(医学版), 2019, 51(4): 628-631.
[11] 曾鸿,容晓莹,张小青,郭向阳. 肾癌伴下腔静脉癌栓手术中应用回收式自体输血联合白细胞滤器2例[J]. 北京大学学报(医学版), 2017, 49(4): 736-739.
[12] 陈立华,杨艺,魏群,李运军,李文德,高进宝,于斌,赵浩,徐如祥. 颞下-乙状窦后联合锁孔入路显微手术治疗岩斜区脑膜瘤[J]. 北京大学学报(医学版), 2016, 48(4): 738-742.
[13] 王振宇, 谢京城, 马长成, 刘彬, 陈晓东, 李振东, 孙建军. 枕下扩大外侧入路手术切除枕大孔区脑膜瘤[J]. 北京大学学报(医学版), 2004, 36(6): 634-636.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!