北京大学学报(医学版) ›› 2019, Vol. 51 ›› Issue (5): 835-839. doi: 10.19723/j.issn.1671-167X.2019.05.008
贾子昌1,卞焕菊2,李选1,栾景源1,王昌明1,刘启佳1,韩金涛1,△()
Zi-chang JIA1,Huan-ju BIAN2,Xuan LI1,Jing-yuan LUAN1,Chang-ming WANG1,Qi-jia LIU1,Jin-tao HAN1,△()
摘要:
目的:评估Neuroform EZ支架治疗复杂症状性重度颅内动脉粥样硬化性狭窄(intracranial atherosclerotic stenosis,ICAS)的安全性和有效性。方法:回顾性分析2016年1月至2017年12月于北京大学第三医院介入血管外科选用经微导管释放的Neuroform EZ支架治疗的18例复杂症状性ICAS(手术路径严重迂曲、病变>10 mm或闭塞、病变接近分叉、狭窄附近合并动脉瘤等)的患者资料。主要终点事件定义为术后30 d内任何脑卒中事件(含缺血性和出血性)或任何原因引起的死亡,次要终点事件为支架治疗成功以及随访期间支架内再狭窄(狭窄率>50%)。结果:18例均获得技术成功,血管狭窄率从85%±7%降为18%±6%,主要终点事件发生率为5.6%(1/18),为左椎动脉串联病变患者术后出现基底节区梗塞。无出血性脑卒中及死亡并发症,1例合并狭窄附近动脉瘤患者予二期栓塞治疗。12例获得数字减影血管造影(digital subtraction angiography,DSA)随访,随访 8~26个月,平均随访时间(16±8)个月,有2例患者(2/12,16.7%)出现支架内再狭窄,其中1例为症状性再狭窄,予支架内球囊扩张治疗。结论:Neuroform EZ支架治疗经严格选择的复杂症状性重度ICAS是安全有效的,较传统支架有其优势。
中图分类号:
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