北京大学学报(医学版) ›› 2026, Vol. 58 ›› Issue (2): 365-371. doi: 10.19723/j.issn.1671-167X.2026.02.022

• 论著 • 上一篇    下一篇

动态导航辅助环钻取骨的准确性

刘嘉昱, 祝宁, 张育祯, 高贤明, 张宇*()   

  1. 北京大学口腔医学院·口腔医院种植科, 国家口腔医学中心, 国家口腔疾病临床医学研究中心, 口腔生物材料和数字诊疗装备国家工程研究中心, 口腔数字医学北京市重点实验室, 北京 100081
  • 收稿日期:2024-02-05 出版日期:2026-04-18 发布日期:2026-02-25
  • 通讯作者: 张宇
  • 基金资助:
    北京大学口腔医学院2022年临床新技术新疗法项目(PKUSSNCT-22A01)

Accuracy of dynamic navigation-assisted trephine method for bone harvesting

Jiayu LIU, Ning ZHU, Yuchen CHANG, Xianming GAO, Yu ZHANG*()   

  1. Department of Oral Implantology, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China
  • Received:2024-02-05 Online:2026-04-18 Published:2026-02-25
  • Contact: Yu ZHANG
  • Supported by:
    the Program for New Clinical Techniques and Therapies of Peking University School and Hospital of Stomatology(PKUSSNCT-22A01)

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摘要:

目的: 评估在颏部和外斜线区域使用动态导航辅助环钻法取骨的准确性。方法: 设计并使用3D打印技术以聚醚酮酮(polyetheretherketone, PEKK)材料制作10个标准下颌骨模型以模拟天然下颌骨的力学性能。实验前拍摄模型的锥形束CT(cone beam CT,CBCT),参数设定为管电压70 kV、管电流70 mA、体积像素250 μm。将数据导入动态导航软件(迪凯尔公司,中国),并在颏部(距前牙≥15 mm)和外斜线区域(距磨牙≥6 mm)各2个常规手术位点设计具有相同深度(6 mm)和直径(8 mm)的圆柱形预备道。使用20 mm和50 mm长度的球钻完成导航系统标定后,在动态导航辅助下于每个位点使用8 mm外径的环钻完成共计40个位点的预备道制备。拍摄术后模型的CBCT,利用Mimics 20.0软件(Materialise公司,比利时)将实际预备道拟合成标准圆柱体,并基于金属配准标记将实际预备道与设计预备道叠加,测量进入中心点偏差、结束中心点偏差、深度偏差及中心轴角度偏差,比较不同供区的准确性差异。结果: 动态导航辅助环钻取骨的进入及结束中心点误差分别为(1.91±0.69) mm和(1.54±0.66) mm,深度误差为(-0.83±0.77) mm,中心轴角度差为3.02°±0.38°,其中在颏部和外斜线的进入中心点误差分别为(1.32±0.36) mm和(2.50±0.35) mm(P<0.01),结束中心点误差分别为(1.06±0.31) mm和(2.02±0.56) mm(P<0.01),深度误差分别为(-0.30±0.52) mm和(-1.38±0.57) mm(P<0.01),中心轴角度差分别为3.03°±0.38°和3.00°±0.39°(P=0.80)。结论: 在本研究的局限性范围内,动态导航辅助环钻取骨有着良好的准确性表现,其中颏部取骨准确性优于外斜线区域,这可能与两个区域的骨表面形态及手术操作等因素的差异有关;本研究结果为动态导航辅助环钻法取骨技术的临床应用提供了参考数据,但仍需要后续临床研究进一步验证其准确性。

关键词: 牙种植, 外科导航系统, 骨移植

Abstract:

Objective: To evaluate the positional accuracy of dynamic navigation-assisted trephine bone harvesting in the symphysis and external oblique ridge. Methods: Ten standardized mandibular models were 3D-printed using polyetheretherketone (PEEK), mimicking natural mandibular mechanical properties. Pre-operative cone beam CT (CBCT) scans (70 kV, 70 mA, 0.25 mm×0.25 mm ×0.25 mm voxel) were acquired, and data were imported into dynamic navigation software (Dcarer, China). Two donor sites were designed in both the symphysis (≥15 mm from anterior teeth) and external oblique ridge (≥6 mm from molars), with 8 mm-diameter, 6 mm-deep cylindrical osteotomy tracts planned for each site.After calibrating the navigation system with 20 mm and 50 mm spherical burs, an 8 mm outer-diameter trephine prepared 40 tracts under real-time guidance. Post-operative CBCT scans were taken, and Mimics 20.0 software fitted actual tracts to standard cylinders. Superimposing actual and designed tracts via metal registration markers, we measured coronal/apical center point deviation, depth deviation, and axis angle deviation in order to compare site-specific accuracy. Results: Deviations of the dynamic navigation-assisted trephine method for bone harvesting was (1.91±0.69) mm at the coronal center point, (1.54±0.66) mm at the apical center point, (-0.83±0.77) mm at the depth of the apical center point and 3.02°±0.38° at the axis angle. The four deviations in symphysis and external oblique ridge were (1.32±0.36) mm and (2.50±0.35) mm at the coronal center point (P < 0.01), (1.06± 0.31) mm and (2.02±0.56) mm at the apical center point (P < 0.01), (-0.30±0.52) mm and (-1.38±0.57) mm at the depth of apical center point (P < 0.01), 3.03°± 0.38° and 3.00°± 0.39° at axis angle (P=0.80). Conclusion: Within the limitations of this study, dynamic navigation-assisted trephine harvesting shows good accuracy. The symphysis exhibits higher accuracy than the external oblique ridge, possibly due to surface morphology and operability differences. These findings support its clinical potential, but future clinical studies are needed to validate results.

Key words: Dental implant, Surgical navigation systems, Bone transplantation

中图分类号: 

  • R783

图1

动态导航辅助环钻取骨准确性的体外研究流程图"

图2

导航辅助环钻取骨的方案设计及实施"

图3

动态导航辅助环钻取骨准确性的数据分析"

图4

动态导航辅助环钻取骨准确性的评价指标"

表1

动态导航辅助环钻取骨误差"

Deviations n ${\bar x}$±s Minimum Maximum
Coronal center point/mm 40 1.91±0.69 0.64 3.12
Apical center point/mm 40 1.54±0.66 0.41 2.94
Depth of apical center point/mm 40 -0.84±0.77 -2.22 0.63
Axis angle/(°) 40 3.02±0.38 2.11 3.72

表2

动态导航辅助环钻取骨在颏部及外斜线区域的误差"

Deviations Donor sites n ${\bar x}$±s Minimum Maximum t P
Coronal center point/mm Symphysis 20 1.32±0.36 0.64 1.98 -10.42 <0.01
External oblique line 20 2.50±0.35 1.98 3.12
Apical center point/mm Symphysis 20 1.06±0.31 0.41 1.57 -6.70 <0.01
External oblique line 20 2.02±0.56 0.86 2.94
Depth of apical center point/mm Symphysis 20 -0.30±0.52 -1.13 0.63 4.81 <0.01
External oblique line 20 -1.38±0.57 -2.22 -0.55
Axis angle/(°) Symphysis 20 3.03±0.38 2.43 3.72 0.26 0.80
External oblique line 20 3.00±0.39 2.11 3.56

图5

在颏部外斜线区使用动态导航辅助环钻取骨准确性的差异分析"

1
Lichte P , Pape HC , Pufe T , et al. Scaffolds for bone healing: Concepts, materials and evidence[J]. Injury, 2011, 42 (6): 569- 573.

doi: 10.1016/j.injury.2011.03.033
2
Omara M , Abdelwahed N , Ahmed M , et al. Simultaneous implant placement with ridge augmentation using an autogenous bone ring transplant[J]. Int J Oral Maxillofac Surg, 2016, 45 (4): 535- 544.

doi: 10.1016/j.ijom.2015.11.001
3
Khoury F , Hanser T . Mandibular bone block harvesting from the retromolar region: A 10-year prospective clinical study[J]. Int J Oral Maxillofac Implants, 2015, 30 (3): 688- 697.

doi: 10.11607/jomi.4117
4
Senos R , Hankenson KD . Calvaria critical-size defects in rats using piezoelectric equipment: A comparison with the classic trephine[J]. Injury, 2020, 51 (7): 1509- 1514.

doi: 10.1016/j.injury.2020.04.041
5
Abdulrazaq SS , Issa SA , Abdulrazzak NJ . Evaluation of the trephine method in harvesting bone graft from the anterior iliac crest for oral and maxillofacial reconstructive surgery[J]. J Craniofacial Surg, 2015, 26 (8): e744- e746.

doi: 10.1097/SCS.0000000000002177
6
Chandra R , Suvvari N , Reddy A . Trephine core procedure versus bone-added osteotome sinus floor elevation in the augmentation of the sinus floor: A comparative clinical and radiographic study[J]. Int J Oral Maxillofac Implants, 2018, 33 (2): 425- 432.

doi: 10.11607/jomi.5998
7
Takamoto M , Takechi M , Ohta K , et al. Risk of bacterial contamination of bone harvesting devices used for autogenous bone graft in implant surgery[J]. Head Face Med, 2013, 9 (1): 3.

doi: 10.1186/1746-160X-9-3
8
Maridati P , Dellavia C , Pellegrini G , et al. Histologic and radiographic comparison of bone scraper and trephine bur for autologous bone harvesting in maxillary sinus augmentation[J]. Int J Oral Maxillofac Implants, 2015, 30 (5): 1128.
9
Miron RJ , Gruber R , Hedbom E , et al. Bigger size and defatting of bone chips will increase cup stability[J]. Clin Implant Dent Rel Res, 2013, 15 (4): 481- 489.

doi: 10.1111/j.1708-8208.2012.00440.x
10
Urban IA , Monje A , Lozada JL , et al. Long-term evaluation of peri-implant bone level after reconstruction of severely atrophic edentulous maxilla via vertical and horizontal guided bone regeneration in combination with sinus augmentation: A case series with 1 to 15 years of loading[J]. Clin Implant Dent Rel Res, 2017, 19 (1): 46- 55.

doi: 10.1111/cid.12431
11
Streckbein P , Kähling C , Wilbrand JF , et al. Horizontal alveolar ridge augmentation using autologous press fit bone cylinders and micro-lag-screw fixation: Technical note and initial experience[J]. J Cranio Maxillofac Surg, 2014, 42 (5): 387- 391.

doi: 10.1016/j.jcms.2014.01.011
12
Giesenhagen B . Klinische fünfjahresergebnisse nach einzeitiger augmentation mit autologen knochenringen und ankylos-implantaten im atrophierten unterkiefer[J]. Zeitschrift Für Zahnärztliche Implantologie, 2015, 31 (1): 52- 62.
13
Streckbein P , Meier M , Kähling C , et al. Donor-site morbidity after retromolar bone harvesting using a standardised press fit cylinder protocol[J]. Materials, 2019, 12 (22): 3802.

doi: 10.3390/ma12223802
14
Yeung R . Simultaneous placement of implant and bone graft in the anterior maxilla: A case report[J]. Int J Oral Maxillofac Implants, 2004, 19 (6): 892- 895.
15
Lin WS , Yang CC , Polido WD , et al. CAD-CAM cobalt-chromium surgical template for static computer-aided implant surgery: A dental technique[J]. J Prosthet Dent, 2020, 123 (1): 42- 44.

doi: 10.1016/j.prosdent.2019.04.014
16
Zhu N , Liu J , Ma T , et al. A fully digital workflow for prosthetically driven alveolar augmentation with intraoral bone block and implant rehabilitation in an atrophic anterior maxilla[J]. J Prosthet Dent, 2023, 130 (5): 668- 673.

doi: 10.1016/j.prosdent.2021.11.034
17
Block MS , Emery RW . Static or dynamic navigation for implant placement-choosing the method of guidance[J]. J Oral Maxillofac Surg, 2016, 74 (2): 269- 277.

doi: 10.1016/j.joms.2015.09.022
18
Vasak C , Watzak G , Gahleitner A , et al. Computed tomography-based evaluation of template (NobelGuideTM)-guided implant positions: A prospective radiological study[J]. Clin Oral Implants Res, 2011, 22 (10): 1157- 1163.

doi: 10.1111/j.1600-0501.2010.02070.x
19
Panchal N , Mahmood L , Retana A , et al. Dynamic navigation for dental implant surgery[J]. Oral Maxillofac Surg Clin N Am, 2019, 31 (4): 539- 547.

doi: 10.1016/j.coms.2019.08.001
20
刘思民, 赵一姣, 王晓燕, 等. 动态导航下不同深度环钻定位精确度的体外评价[J]. 北京大学学报(医学版), 2022, 54 (2): 146- 152.

doi: 10.19723/j.issn.1671-167X.2022.01.023
21
Wu D , Zhou L , Yang J , et al. Accuracy of dynamic navigation compared to static surgical guide for dental implant placement[J]. Int J Implant Dent, 2020, 6 (1): 78.

doi: 10.1186/s40729-020-00272-0
22
Cecchetti F , Di Girolamo M , Ippolito DG , et al. Computer-guided implant surgery: Analysis of dynamic navigation systems and digital accuracy[J]. J Bio Regulators Homeostatic Agents, 2020, 34 (3 Suppl 1): 9- 17.
23
Ma L , Jiang W , Zhang B , et al. Augmented reality surgical navigation with accurate CBCT-patient registration for dental implant placement[J]. Med Biol Eng Comput, 2019, 57 (1): 47- 57.

doi: 10.1007/s11517-018-1861-9
24
满毅, 周楠, 杨醒眉. 动态实时导航在口腔种植领域中的临床应用及新进展[J]. 口腔疾病防治, 2020, 28 (6): 341- 348.
25
Tao B , Shen Y , Sun Y , et al. Comparative accuracy of cone-beam CT and conventional multislice computed tomography for real-time navigation in zygomatic implant surgery[J]. Clin Implant Dent Rel Res, 2020, 22 (6): 747- 755.

doi: 10.1111/cid.12958
26
陶宝鑫, 蓝耕良, 黄伟, 等. 动态导航技术辅助无牙颌种植精度分析[J]. 上海交通大学学报(医学版), 2022, 42 (9): 1353- 1360.
27
王磊, 伍颖颖, 满毅. 动态导航技术中植入位点骨质量对种植精度的影响[J]. 口腔颌面外科杂志, 2022, 32 (3): 174- 181.
28
Wei SM , Zhu Y , Wei JX , et al. Accuracy of dynamic navigation in implant surgery: A systematic review and meta-analysis[J]. Clin Oral Implants Res, 2021, 32 (4): 383- 393.

doi: 10.1111/clr.13719
29
Aydemir CA , Arısan V . Accuracy of dental implant placement via dynamic navigation or the freehand method: A split-mouth randomized controlled clinical trial[J]. Clin Oral Implants Res, 2020, 31 (3): 255- 263.

doi: 10.1111/clr.13563
30
Mediavilla Guzmán A , Riad Deglow E , Zubizarreta-Macho á , et al. Accuracy of computer-aided dynamic navigation compared to computer-aided static navigation for dental implant placement: An in vitro study[J]. J Clin Med, 2019, 8 (12): 2123.

doi: 10.3390/jcm8122123
31
林后学, 郭松松, 何佳宜, 等. 下颌骨颏部骨皮质增龄性变化的锥形束CT研究[J]. 中国CT和MRI杂志, 2016, 14 (9): 15- 18.
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